Matrix Proteases in Health and Disease:
Presenting a comprehensive overview of the multifaceted field of proteases in the extracellular matrix environment, this reference focuses on the recently elucidated functions of complex proteolytic systems in physiological and pathological tissue remodeling. The proteases treated include both serin...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Somerset
John Wiley & Sons, Incorporated
2012
|
| Ausgabe: | 2nd ed |
| Schlagworte: | |
| Zusammenfassung: | Presenting a comprehensive overview of the multifaceted field of proteases in the extracellular matrix environment, this reference focuses on the recently elucidated functions of complex proteolytic systems in physiological and pathological tissue remodeling. The proteases treated include both serine proteases such as plasminogen activators and TTSPs, metalloproteases such as MMPs and ADAMS and cysteine protease cathepsins. The text specifically addresses the role of extracellular proteases in cancer cell invasion, stroke and infectious diseases, describing the basic biochemistry behind these disease states, as well as therapeutic strategies based on protease inhibition. With its trans-disciplinary scope, this reference bridges the gap between fundamental research and biomedical and pharmaceutical application, making this required reading for basic and applied scientists in the molecular life sciences |
| Beschreibung: | Description based on publisher supplied metadata and other sources |
| Beschreibung: | 1 online resource (446 pages) |
| ISBN: | 9783527649341 9783527329915 |
Internformat
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| 500 | |a Description based on publisher supplied metadata and other sources | ||
| 520 | |a Presenting a comprehensive overview of the multifaceted field of proteases in the extracellular matrix environment, this reference focuses on the recently elucidated functions of complex proteolytic systems in physiological and pathological tissue remodeling. The proteases treated include both serine proteases such as plasminogen activators and TTSPs, metalloproteases such as MMPs and ADAMS and cysteine protease cathepsins. The text specifically addresses the role of extracellular proteases in cancer cell invasion, stroke and infectious diseases, describing the basic biochemistry behind these disease states, as well as therapeutic strategies based on protease inhibition. With its trans-disciplinary scope, this reference bridges the gap between fundamental research and biomedical and pharmaceutical application, making this required reading for basic and applied scientists in the molecular life sciences | ||
| 650 | 4 | |a Extracellular matrix -- Enzymology | |
| 650 | 4 | |a Extracellular matrix | |
| 650 | 4 | |a Peptide hydrolases | |
| 650 | 4 | |a Proteolytic enzymes -- Physiological effect | |
| 650 | 0 | 7 | |a Proteasen |0 (DE-588)4047521-9 |2 gnd |9 rswk-swf |
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Datensatz im Suchindex
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|---|---|
| any_adam_object | |
| author | Behrendt, Niels |
| author_facet | Behrendt, Niels |
| author_role | aut |
| author_sort | Behrendt, Niels |
| author_variant | n b nb |
| building | Verbundindex |
| bvnumber | BV044049840 |
| collection | ZDB-30-PAD ZDB-38-ESG |
| ctrlnum | (ZDB-30-PAD)EBC1031844 (ZDB-89-EBL)EBL1031844 (ZDB-38-EBR)ebr10657483 (OCoLC)810937691 (DE-599)BVBBV044049840 |
| dewey-full | 611.0182 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 611 - Human anatomy, cytology, histology |
| dewey-raw | 611.0182 |
| dewey-search | 611.0182 |
| dewey-sort | 3611.0182 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 2nd ed |
| format | Electronic eBook |
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| id | DE-604.BV044049840 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:42:10Z |
| institution | BVB |
| isbn | 9783527649341 9783527329915 |
| language | English |
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| publisher | John Wiley & Sons, Incorporated |
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| spelling | Behrendt, Niels Verfasser aut Matrix Proteases in Health and Disease 2nd ed Somerset John Wiley & Sons, Incorporated 2012 © 2011 1 online resource (446 pages) txt rdacontent c rdamedia cr rdacarrier Description based on publisher supplied metadata and other sources Presenting a comprehensive overview of the multifaceted field of proteases in the extracellular matrix environment, this reference focuses on the recently elucidated functions of complex proteolytic systems in physiological and pathological tissue remodeling. The proteases treated include both serine proteases such as plasminogen activators and TTSPs, metalloproteases such as MMPs and ADAMS and cysteine protease cathepsins. The text specifically addresses the role of extracellular proteases in cancer cell invasion, stroke and infectious diseases, describing the basic biochemistry behind these disease states, as well as therapeutic strategies based on protease inhibition. With its trans-disciplinary scope, this reference bridges the gap between fundamental research and biomedical and pharmaceutical application, making this required reading for basic and applied scientists in the molecular life sciences Extracellular matrix -- Enzymology Extracellular matrix Peptide hydrolases Proteolytic enzymes -- Physiological effect Proteasen (DE-588)4047521-9 gnd rswk-swf Extrazelluläre Matrix (DE-588)7530993-2 gnd rswk-swf Extrazelluläre Matrix (DE-588)7530993-2 s Proteasen (DE-588)4047521-9 s 1\p DE-604 Erscheint auch als Druck-Ausgabe Behrendt, Niels Matrix Proteases in Health and Disease 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Behrendt, Niels Matrix Proteases in Health and Disease Extracellular matrix -- Enzymology Extracellular matrix Peptide hydrolases Proteolytic enzymes -- Physiological effect Proteasen (DE-588)4047521-9 gnd Extrazelluläre Matrix (DE-588)7530993-2 gnd |
| subject_GND | (DE-588)4047521-9 (DE-588)7530993-2 |
| title | Matrix Proteases in Health and Disease |
| title_auth | Matrix Proteases in Health and Disease |
| title_exact_search | Matrix Proteases in Health and Disease |
| title_full | Matrix Proteases in Health and Disease |
| title_fullStr | Matrix Proteases in Health and Disease |
| title_full_unstemmed | Matrix Proteases in Health and Disease |
| title_short | Matrix Proteases in Health and Disease |
| title_sort | matrix proteases in health and disease |
| topic | Extracellular matrix -- Enzymology Extracellular matrix Peptide hydrolases Proteolytic enzymes -- Physiological effect Proteasen (DE-588)4047521-9 gnd Extrazelluläre Matrix (DE-588)7530993-2 gnd |
| topic_facet | Extracellular matrix -- Enzymology Extracellular matrix Peptide hydrolases Proteolytic enzymes -- Physiological effect Proteasen Extrazelluläre Matrix |
| work_keys_str_mv | AT behrendtniels matrixproteasesinhealthanddisease |