Prions and prion diseases: new developments
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York
Nova Science
©2012
|
| Schriftenreihe: | Protein biochemistry, synthesis, structure, and cellular functions series
Protein science and engineering |
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 |
| Beschreibung: | Includes bibliographical references and index ""PRIONS AND PRION DISEASES""; ""PRIONS AND PRION DISEASES""; ""CONTENTS ""; ""PREFACE ""; ""NEUROPATHOLOGY OF HUMAN PRION DISEASES ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""THE ROLE OF NEUROPATHOLOGY ""; ""PERFORMING THE AUTOPSY ""; ""NEUROPATHOLOGICAL EXAMINATION""; ""A.) Macroscopy""; ""B.) Work-Up for Histological Evaluation ""; ""C.) Microscopic Assessment ""; ""I.) Spongiform Change of the Neuropil ""; ""a) In Sporadic Forms""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""II) Neuronal Death ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms "" ""SYNAPTIC PATHOLOGY """"III.) Astroglial Proliferation ""; ""IV.) Microglial Activation ""; ""V.) PrP Amyloid Plaques ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VI.) Cerebellar Pathology ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms""; ""RELATIVE RESISTANCE OF HIPPOCAMPUS IN CJD ""; ""VII.) Detection of PrP ""; ""VIIa.) By Immunohistochemistry ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIIb.) By histoblot and Paraffin-Embedded Tissue Blot "" ""VIId.) By Western blot""""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIII.) Co-deposition of other Abnormal Protein Aggregates in CJD ""; ""a) In Sporadic Forms ""; ""b) In Genetic Forms ""; ""c) In Acquired Forms ""; ""IX.) Differential Diagnoses from Autopsy Series ""; ""X.) Neuronal Systems and Their Clinico-Pathological Correlates ""; ""CONCLUSION ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""THE NATURE OF THE INFECTIOUS AGENTS: PRP MODELS OF RESISTANT SPECIES TO PRION DISEASES (DOG, RABBIT AND HORSES)""; ""Abstract""; ""1. Introduction"" ""2. MaterialsandMethods""""3. ResultsandDiscussion""; ""4. Conclusion""; ""Acknowledgments""; ""References""; ""INDUCING TRANSMISSIBLE PRION DISEASES WITH RECOMBINANT FIBRILS: A NEW CONCEPT ON GENESIS AND EVOLUTION OF INFECTIOUS PRIONS ""; ""ABSTRACT ""; ""GENERATING TRANSMISSIBLE PRION DISEASES DE NOVO ""; ""THE MECHANISM OF TRIGGERING PRION DISEASE BY RPRP AMYLOID FIBRILS ""; ""EXPERIMENTAL EVIDENCE SUPPORT THE SECOND MODEL ""; ""THE HYPOTHESIS OF DEFORMED TEMPLATING ""; ""CONFORMATIONAL SWITCHING WITHIN INDIVIDUAL AMYLOID FIBRILS AND STRAIN ADAPTATION PHENOMENON"" ""CROSS-TALK BETWEEN AMYLOIDOGENIC PROTEINS """"REFERENCES ""; ""SYNTHETIC PRIONS ""; ""ABSTRACT""; ""1. INTRODUCTION ""; ""2. STRATEGIES FOR DE NOVO MAMMALIAN PRIONS GENERATION ""; ""2.1. Cell-Free Assay Using Mammalian Prions ""; ""2.2. De Novo Generation of Prions by Mouse Transgenesis ""; ""2.3. In Vitro De Novo Prions by PMCA ""; ""2.4. De Novo Prions by Amyloid Seeding Assay ""; ""2.5. De Novo Prions by Annealing Technique ""; ""2.6. Concluding Remarks and New Emerging Techniques for Prion Detection and Generation ""; ""3. STRUCTURAL BIOLOGY OF NATURAL AND SYNTHETIC PRIONS"" |
| Beschreibung: | ix, 200 pages |
| ISBN: | 1619427680 9781619427686 9781621000273 1621000273 |
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| 245 | 1 | 0 | |a Prions and prion diseases |b new developments |c Jean-Michel Verdier, editor |
| 264 | 1 | |a New York |b Nova Science |c ©2012 | |
| 300 | |a ix, 200 pages | ||
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| 490 | 0 | |a Protein biochemistry, synthesis, structure, and cellular functions series | |
| 490 | 0 | |a Protein science and engineering | |
| 500 | |a Includes bibliographical references and index | ||
| 500 | |a ""PRIONS AND PRION DISEASES""; ""PRIONS AND PRION DISEASES""; ""CONTENTS ""; ""PREFACE ""; ""NEUROPATHOLOGY OF HUMAN PRION DISEASES ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""THE ROLE OF NEUROPATHOLOGY ""; ""PERFORMING THE AUTOPSY ""; ""NEUROPATHOLOGICAL EXAMINATION""; ""A.) Macroscopy""; ""B.) Work-Up for Histological Evaluation ""; ""C.) Microscopic Assessment ""; ""I.) Spongiform Change of the Neuropil ""; ""a) In Sporadic Forms""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""II) Neuronal Death ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms "" | ||
| 500 | |a ""SYNAPTIC PATHOLOGY """"III.) Astroglial Proliferation ""; ""IV.) Microglial Activation ""; ""V.) PrP Amyloid Plaques ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VI.) Cerebellar Pathology ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms""; ""RELATIVE RESISTANCE OF HIPPOCAMPUS IN CJD ""; ""VII.) Detection of PrP ""; ""VIIa.) By Immunohistochemistry ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIIb.) By histoblot and Paraffin-Embedded Tissue Blot "" | ||
| 500 | |a ""VIId.) By Western blot""""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIII.) Co-deposition of other Abnormal Protein Aggregates in CJD ""; ""a) In Sporadic Forms ""; ""b) In Genetic Forms ""; ""c) In Acquired Forms ""; ""IX.) Differential Diagnoses from Autopsy Series ""; ""X.) Neuronal Systems and Their Clinico-Pathological Correlates ""; ""CONCLUSION ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""THE NATURE OF THE INFECTIOUS AGENTS: PRP MODELS OF RESISTANT SPECIES TO PRION DISEASES (DOG, RABBIT AND HORSES)""; ""Abstract""; ""1. Introduction"" | ||
| 500 | |a ""2. MaterialsandMethods""""3. ResultsandDiscussion""; ""4. Conclusion""; ""Acknowledgments""; ""References""; ""INDUCING TRANSMISSIBLE PRION DISEASES WITH RECOMBINANT FIBRILS: A NEW CONCEPT ON GENESIS AND EVOLUTION OF INFECTIOUS PRIONS ""; ""ABSTRACT ""; ""GENERATING TRANSMISSIBLE PRION DISEASES DE NOVO ""; ""THE MECHANISM OF TRIGGERING PRION DISEASE BY RPRP AMYLOID FIBRILS ""; ""EXPERIMENTAL EVIDENCE SUPPORT THE SECOND MODEL ""; ""THE HYPOTHESIS OF DEFORMED TEMPLATING ""; ""CONFORMATIONAL SWITCHING WITHIN INDIVIDUAL AMYLOID FIBRILS AND STRAIN ADAPTATION PHENOMENON"" | ||
| 500 | |a ""CROSS-TALK BETWEEN AMYLOIDOGENIC PROTEINS """"REFERENCES ""; ""SYNTHETIC PRIONS ""; ""ABSTRACT""; ""1. INTRODUCTION ""; ""2. STRATEGIES FOR DE NOVO MAMMALIAN PRIONS GENERATION ""; ""2.1. Cell-Free Assay Using Mammalian Prions ""; ""2.2. De Novo Generation of Prions by Mouse Transgenesis ""; ""2.3. In Vitro De Novo Prions by PMCA ""; ""2.4. De Novo Prions by Amyloid Seeding Assay ""; ""2.5. De Novo Prions by Annealing Technique ""; ""2.6. Concluding Remarks and New Emerging Techniques for Prion Detection and Generation ""; ""3. STRUCTURAL BIOLOGY OF NATURAL AND SYNTHETIC PRIONS"" | ||
| 650 | 4 | |a Prion diseases | |
| 650 | 4 | |a Prions | |
| 650 | 7 | |a SCIENCE / Life Sciences / Biology |2 bisacsh | |
| 650 | 7 | |a SCIENCE / Life Sciences / Microbiology |2 bisacsh | |
| 650 | 7 | |a Prion diseases |2 fast | |
| 650 | 7 | |a Prions |2 fast | |
| 650 | 4 | |a Prions | |
| 650 | 4 | |a Prion diseases | |
| 700 | 1 | |a Verdier, Jean-Michel |e Sonstige |4 oth | |
| 912 | |a ZDB-4-EBA | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-029370012 | ||
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| dewey-ones | 579 - Microorganisms, fungi & algae |
| dewey-raw | 579.2/9 |
| dewey-search | 579.2/9 |
| dewey-sort | 3579.2 19 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:39:49Z |
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| isbn | 1619427680 9781619427686 9781621000273 1621000273 |
| language | English |
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| physical | ix, 200 pages |
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| series2 | Protein biochemistry, synthesis, structure, and cellular functions series Protein science and engineering |
| spelling | Prions and prion diseases new developments Jean-Michel Verdier, editor New York Nova Science ©2012 ix, 200 pages txt rdacontent c rdamedia cr rdacarrier Protein biochemistry, synthesis, structure, and cellular functions series Protein science and engineering Includes bibliographical references and index ""PRIONS AND PRION DISEASES""; ""PRIONS AND PRION DISEASES""; ""CONTENTS ""; ""PREFACE ""; ""NEUROPATHOLOGY OF HUMAN PRION DISEASES ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""THE ROLE OF NEUROPATHOLOGY ""; ""PERFORMING THE AUTOPSY ""; ""NEUROPATHOLOGICAL EXAMINATION""; ""A.) Macroscopy""; ""B.) Work-Up for Histological Evaluation ""; ""C.) Microscopic Assessment ""; ""I.) Spongiform Change of the Neuropil ""; ""a) In Sporadic Forms""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""II) Neuronal Death ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms "" ""SYNAPTIC PATHOLOGY """"III.) Astroglial Proliferation ""; ""IV.) Microglial Activation ""; ""V.) PrP Amyloid Plaques ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VI.) Cerebellar Pathology ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms""; ""RELATIVE RESISTANCE OF HIPPOCAMPUS IN CJD ""; ""VII.) Detection of PrP ""; ""VIIa.) By Immunohistochemistry ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIIb.) By histoblot and Paraffin-Embedded Tissue Blot "" ""VIId.) By Western blot""""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIII.) Co-deposition of other Abnormal Protein Aggregates in CJD ""; ""a) In Sporadic Forms ""; ""b) In Genetic Forms ""; ""c) In Acquired Forms ""; ""IX.) Differential Diagnoses from Autopsy Series ""; ""X.) Neuronal Systems and Their Clinico-Pathological Correlates ""; ""CONCLUSION ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""THE NATURE OF THE INFECTIOUS AGENTS: PRP MODELS OF RESISTANT SPECIES TO PRION DISEASES (DOG, RABBIT AND HORSES)""; ""Abstract""; ""1. Introduction"" ""2. MaterialsandMethods""""3. ResultsandDiscussion""; ""4. Conclusion""; ""Acknowledgments""; ""References""; ""INDUCING TRANSMISSIBLE PRION DISEASES WITH RECOMBINANT FIBRILS: A NEW CONCEPT ON GENESIS AND EVOLUTION OF INFECTIOUS PRIONS ""; ""ABSTRACT ""; ""GENERATING TRANSMISSIBLE PRION DISEASES DE NOVO ""; ""THE MECHANISM OF TRIGGERING PRION DISEASE BY RPRP AMYLOID FIBRILS ""; ""EXPERIMENTAL EVIDENCE SUPPORT THE SECOND MODEL ""; ""THE HYPOTHESIS OF DEFORMED TEMPLATING ""; ""CONFORMATIONAL SWITCHING WITHIN INDIVIDUAL AMYLOID FIBRILS AND STRAIN ADAPTATION PHENOMENON"" ""CROSS-TALK BETWEEN AMYLOIDOGENIC PROTEINS """"REFERENCES ""; ""SYNTHETIC PRIONS ""; ""ABSTRACT""; ""1. INTRODUCTION ""; ""2. STRATEGIES FOR DE NOVO MAMMALIAN PRIONS GENERATION ""; ""2.1. Cell-Free Assay Using Mammalian Prions ""; ""2.2. De Novo Generation of Prions by Mouse Transgenesis ""; ""2.3. In Vitro De Novo Prions by PMCA ""; ""2.4. De Novo Prions by Amyloid Seeding Assay ""; ""2.5. De Novo Prions by Annealing Technique ""; ""2.6. Concluding Remarks and New Emerging Techniques for Prion Detection and Generation ""; ""3. STRUCTURAL BIOLOGY OF NATURAL AND SYNTHETIC PRIONS"" Prion diseases Prions SCIENCE / Life Sciences / Biology bisacsh SCIENCE / Life Sciences / Microbiology bisacsh Prion diseases fast Prions fast Verdier, Jean-Michel Sonstige oth |
| spellingShingle | Prions and prion diseases new developments Prion diseases Prions SCIENCE / Life Sciences / Biology bisacsh SCIENCE / Life Sciences / Microbiology bisacsh Prion diseases fast Prions fast |
| title | Prions and prion diseases new developments |
| title_auth | Prions and prion diseases new developments |
| title_exact_search | Prions and prion diseases new developments |
| title_full | Prions and prion diseases new developments Jean-Michel Verdier, editor |
| title_fullStr | Prions and prion diseases new developments Jean-Michel Verdier, editor |
| title_full_unstemmed | Prions and prion diseases new developments Jean-Michel Verdier, editor |
| title_short | Prions and prion diseases |
| title_sort | prions and prion diseases new developments |
| title_sub | new developments |
| topic | Prion diseases Prions SCIENCE / Life Sciences / Biology bisacsh SCIENCE / Life Sciences / Microbiology bisacsh Prion diseases fast Prions fast |
| topic_facet | Prion diseases Prions SCIENCE / Life Sciences / Biology SCIENCE / Life Sciences / Microbiology |
| work_keys_str_mv | AT verdierjeanmichel prionsandpriondiseasesnewdevelopments |