Gene expression profiling by microarrays: clinical implications
Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. Thi...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2006
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| Schlagworte: | |
| Online-Zugang: | BSB01 FHN01 Volltext |
| Zusammenfassung: | Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology |
| Beschreibung: | Title from publisher's bibliographic system (viewed on 05 Oct 2015) |
| Beschreibung: | 1 online resource (xiv, 246 pages) |
| ISBN: | 9780511545849 |
| DOI: | 10.1017/CBO9780511545849 |
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| contents | Technique of microarrays : microarray platforms / Sven de Vos -- Quantitative quality control of microarray experiments : toward accurate gene expression measurements / Xujing Wang and Martin J. Hessner -- Statistical analysis of gene expression data / David A. Elashoff -- Genomic stratification in patients with heart failure / Tara A. Bullard [and others] -- Gene expression profiling for the diagnosis of acute leukemias / Torsten Haferlach [and others] -- Gene expression profiling can distinguish tumor subclasses of breast carcinomas / Ingrid A. Hedenfalk -- Gene expression profiling in lymphoid malignancies / Christof Burek [and others] -- mRNA profiling of pancreatic beta-cells : investigating mechanisms of diabetes / Leentje Van Lommel [and others] -- Prediction of response and resistance to treatment by gene expression profiling / Philipp Kiewe and Wolf-Karsten Hofmann |
| ctrlnum | (ZDB-20-CBO)CR9780511545849 (OCoLC)850190694 (DE-599)BVBBV043944414 |
| dewey-full | 572.865 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.865 |
| dewey-search | 572.865 |
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| dewey-tens | 570 - Biology |
| discipline | Biologie |
| doi_str_mv | 10.1017/CBO9780511545849 |
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| language | English |
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| spelling | Gene expression profiling by microarrays clinical implications edited by Wolf-Karsten Hofmann Cambridge Cambridge University Press 2006 1 online resource (xiv, 246 pages) txt rdacontent c rdamedia cr rdacarrier Title from publisher's bibliographic system (viewed on 05 Oct 2015) Technique of microarrays : microarray platforms / Sven de Vos -- Quantitative quality control of microarray experiments : toward accurate gene expression measurements / Xujing Wang and Martin J. Hessner -- Statistical analysis of gene expression data / David A. Elashoff -- Genomic stratification in patients with heart failure / Tara A. Bullard [and others] -- Gene expression profiling for the diagnosis of acute leukemias / Torsten Haferlach [and others] -- Gene expression profiling can distinguish tumor subclasses of breast carcinomas / Ingrid A. Hedenfalk -- Gene expression profiling in lymphoid malignancies / Christof Burek [and others] -- mRNA profiling of pancreatic beta-cells : investigating mechanisms of diabetes / Leentje Van Lommel [and others] -- Prediction of response and resistance to treatment by gene expression profiling / Philipp Kiewe and Wolf-Karsten Hofmann Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology Gene expression Medical genetics Genexpression (DE-588)4020136-3 gnd rswk-swf Microarray (DE-588)4544227-7 gnd rswk-swf Genexpression (DE-588)4020136-3 s Microarray (DE-588)4544227-7 s 1\p DE-604 Hofmann, Wolf-Karsten edt Erscheint auch als Druckausgabe 978-0-521-85396-5 https://doi.org/10.1017/CBO9780511545849 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Gene expression profiling by microarrays clinical implications Technique of microarrays : microarray platforms / Sven de Vos -- Quantitative quality control of microarray experiments : toward accurate gene expression measurements / Xujing Wang and Martin J. Hessner -- Statistical analysis of gene expression data / David A. Elashoff -- Genomic stratification in patients with heart failure / Tara A. Bullard [and others] -- Gene expression profiling for the diagnosis of acute leukemias / Torsten Haferlach [and others] -- Gene expression profiling can distinguish tumor subclasses of breast carcinomas / Ingrid A. Hedenfalk -- Gene expression profiling in lymphoid malignancies / Christof Burek [and others] -- mRNA profiling of pancreatic beta-cells : investigating mechanisms of diabetes / Leentje Van Lommel [and others] -- Prediction of response and resistance to treatment by gene expression profiling / Philipp Kiewe and Wolf-Karsten Hofmann Gene expression Medical genetics Genexpression (DE-588)4020136-3 gnd Microarray (DE-588)4544227-7 gnd |
| subject_GND | (DE-588)4020136-3 (DE-588)4544227-7 |
| title | Gene expression profiling by microarrays clinical implications |
| title_auth | Gene expression profiling by microarrays clinical implications |
| title_exact_search | Gene expression profiling by microarrays clinical implications |
| title_full | Gene expression profiling by microarrays clinical implications edited by Wolf-Karsten Hofmann |
| title_fullStr | Gene expression profiling by microarrays clinical implications edited by Wolf-Karsten Hofmann |
| title_full_unstemmed | Gene expression profiling by microarrays clinical implications edited by Wolf-Karsten Hofmann |
| title_short | Gene expression profiling by microarrays |
| title_sort | gene expression profiling by microarrays clinical implications |
| title_sub | clinical implications |
| topic | Gene expression Medical genetics Genexpression (DE-588)4020136-3 gnd Microarray (DE-588)4544227-7 gnd |
| topic_facet | Gene expression Medical genetics Genexpression Microarray |
| url | https://doi.org/10.1017/CBO9780511545849 |
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