Principles of pharmacogenetics and pharmacogenomics:
The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or l...
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| Weitere Verfasser: | , , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2012
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| Schlagworte: | |
| Online-Zugang: | BSB01 FHN01 Volltext |
| Zusammenfassung: | The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine – not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences |
| Beschreibung: | Title from publisher's bibliographic system (viewed on 05 Oct 2015) |
| Beschreibung: | 1 online resource (xii, 269 pages) |
| ISBN: | 9781139051194 |
| DOI: | 10.1017/CBO9781139051194 |
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| 505 | 8 | |a pt. I. Critical Concepts. Introduction to population diversity and genetic testing / James K. Burmester, Ingrid Glurich, Kimberly Pillsbury and Michael D. Caldwell -- Genotyping technologies / Sharon Marsh and Cristi R. King -- Pharmacokinetics: absorption, distribution, metabolism, excretion / Terry Blaschke -- Overview: adverse drug reactions / Matthew Nelson -- PharmGKB, a centralized resource for pharmacogenomic knowledge and discovery / Li Gong and Teri E. Klein -- DrugBank / David S. Wishart -- Ethical considerations for pharmacogenomics: privacy and confidentiality / Sandra Lee -- Informed consent in pharmacogenomic research and treatment / Mark Rothstein -- Legal trends driving the clinical translation of pharmacogenomics / Barbara Evans -- pt. II. Therapeutic Areas. Pharmacogenetics of oncologic drugs / Mark Ratain, Uchenna Njaju and Eileen Dolan -- Pharmacogenetics of cardiovascular drugs / Michael Stein and Danny Kurnik -- Pharmacogenomics of statin-induced muscle toxicity / Ronald M. Krauss, Russell A. Wilke, Melissa Antonik and Elenita Kanin -- Pharmacogenomics of the drug-induced long QT syndrome / Dan M. Roden, Prince J. Kannankeril, Stefan Kaab and Dawood Darbar -- Pharmacogenetics of diabetes drugs / O.H. Klungel and Mark C.H. DeGroot -- Pharmacogenetics of respiratory drugs / Kelan Tantisira and Scott Weiss -- Pharmacogenomics for acid-related gastrointestinal drugs / Takahisa Furuta -- Pharmacogenetics of rheumatoid arthritis drugs / Robert M. Plenge, Yvonne C. Lee, Souomya Raychaudhuri and Daniel H. Solomon -- Pharmacogenomics of obstetric drugs / David Haas and Jamie Renbarger -- Pharmacogenomics of psychiatric drugs / David Mrazek | |
| 505 | 8 | |a Pharmacogenomics of pain and anesthesia drugs / Evan Kharasch and Konrad Meissner -- Pharmacogenetics of HIV and antiretroviral drugs / Amalio Telenti -- Pharmacogenomics in pediatrics / Jennifer A. Lowry and J. Steven Leeder -- Pharmacogenomics in fetal and neonatal medicine / Yair Blumenfeld | |
| 520 | |a The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine – not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences | ||
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Datensatz im Suchindex
| _version_ | 1804176885709537280 |
|---|---|
| any_adam_object | |
| author2 | Altman, Russ Flockhart, David A Goldstein, David B |
| author2_role | edt edt edt |
| author2_variant | r a ra d a f da daf d b g db dbg |
| author_facet | Altman, Russ Flockhart, David A Goldstein, David B |
| building | Verbundindex |
| bvnumber | BV043942616 |
| collection | ZDB-20-CBO |
| contents | pt. I. Critical Concepts. Introduction to population diversity and genetic testing / James K. Burmester, Ingrid Glurich, Kimberly Pillsbury and Michael D. Caldwell -- Genotyping technologies / Sharon Marsh and Cristi R. King -- Pharmacokinetics: absorption, distribution, metabolism, excretion / Terry Blaschke -- Overview: adverse drug reactions / Matthew Nelson -- PharmGKB, a centralized resource for pharmacogenomic knowledge and discovery / Li Gong and Teri E. Klein -- DrugBank / David S. Wishart -- Ethical considerations for pharmacogenomics: privacy and confidentiality / Sandra Lee -- Informed consent in pharmacogenomic research and treatment / Mark Rothstein -- Legal trends driving the clinical translation of pharmacogenomics / Barbara Evans -- pt. II. Therapeutic Areas. Pharmacogenetics of oncologic drugs / Mark Ratain, Uchenna Njaju and Eileen Dolan -- Pharmacogenetics of cardiovascular drugs / Michael Stein and Danny Kurnik -- Pharmacogenomics of statin-induced muscle toxicity / Ronald M. Krauss, Russell A. Wilke, Melissa Antonik and Elenita Kanin -- Pharmacogenomics of the drug-induced long QT syndrome / Dan M. Roden, Prince J. Kannankeril, Stefan Kaab and Dawood Darbar -- Pharmacogenetics of diabetes drugs / O.H. Klungel and Mark C.H. DeGroot -- Pharmacogenetics of respiratory drugs / Kelan Tantisira and Scott Weiss -- Pharmacogenomics for acid-related gastrointestinal drugs / Takahisa Furuta -- Pharmacogenetics of rheumatoid arthritis drugs / Robert M. Plenge, Yvonne C. Lee, Souomya Raychaudhuri and Daniel H. Solomon -- Pharmacogenomics of obstetric drugs / David Haas and Jamie Renbarger -- Pharmacogenomics of psychiatric drugs / David Mrazek Pharmacogenomics of pain and anesthesia drugs / Evan Kharasch and Konrad Meissner -- Pharmacogenetics of HIV and antiretroviral drugs / Amalio Telenti -- Pharmacogenomics in pediatrics / Jennifer A. Lowry and J. Steven Leeder -- Pharmacogenomics in fetal and neonatal medicine / Yair Blumenfeld |
| ctrlnum | (ZDB-20-CBO)CR9781139051194 (OCoLC)851059582 (DE-599)BVBBV043942616 |
| dewey-full | 615/.7 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.7 |
| dewey-search | 615/.7 |
| dewey-sort | 3615 17 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1017/CBO9781139051194 |
| format | Electronic eBook |
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| id | DE-604.BV043942616 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:39:18Z |
| institution | BVB |
| isbn | 9781139051194 |
| language | English |
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| physical | 1 online resource (xii, 269 pages) |
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| spelling | Principles of pharmacogenetics and pharmacogenomics edited by Russ B. Altman, David Flockhart, David B. Goldstein Principles of pharmacogenetics & pharmacogenomics Cambridge Cambridge University Press 2012 1 online resource (xii, 269 pages) txt rdacontent c rdamedia cr rdacarrier Title from publisher's bibliographic system (viewed on 05 Oct 2015) pt. I. Critical Concepts. Introduction to population diversity and genetic testing / James K. Burmester, Ingrid Glurich, Kimberly Pillsbury and Michael D. Caldwell -- Genotyping technologies / Sharon Marsh and Cristi R. King -- Pharmacokinetics: absorption, distribution, metabolism, excretion / Terry Blaschke -- Overview: adverse drug reactions / Matthew Nelson -- PharmGKB, a centralized resource for pharmacogenomic knowledge and discovery / Li Gong and Teri E. Klein -- DrugBank / David S. Wishart -- Ethical considerations for pharmacogenomics: privacy and confidentiality / Sandra Lee -- Informed consent in pharmacogenomic research and treatment / Mark Rothstein -- Legal trends driving the clinical translation of pharmacogenomics / Barbara Evans -- pt. II. Therapeutic Areas. Pharmacogenetics of oncologic drugs / Mark Ratain, Uchenna Njaju and Eileen Dolan -- Pharmacogenetics of cardiovascular drugs / Michael Stein and Danny Kurnik -- Pharmacogenomics of statin-induced muscle toxicity / Ronald M. Krauss, Russell A. Wilke, Melissa Antonik and Elenita Kanin -- Pharmacogenomics of the drug-induced long QT syndrome / Dan M. Roden, Prince J. Kannankeril, Stefan Kaab and Dawood Darbar -- Pharmacogenetics of diabetes drugs / O.H. Klungel and Mark C.H. DeGroot -- Pharmacogenetics of respiratory drugs / Kelan Tantisira and Scott Weiss -- Pharmacogenomics for acid-related gastrointestinal drugs / Takahisa Furuta -- Pharmacogenetics of rheumatoid arthritis drugs / Robert M. Plenge, Yvonne C. Lee, Souomya Raychaudhuri and Daniel H. Solomon -- Pharmacogenomics of obstetric drugs / David Haas and Jamie Renbarger -- Pharmacogenomics of psychiatric drugs / David Mrazek Pharmacogenomics of pain and anesthesia drugs / Evan Kharasch and Konrad Meissner -- Pharmacogenetics of HIV and antiretroviral drugs / Amalio Telenti -- Pharmacogenomics in pediatrics / Jennifer A. Lowry and J. Steven Leeder -- Pharmacogenomics in fetal and neonatal medicine / Yair Blumenfeld The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine – not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences Pharmacogenetics Pharmakogenetik (DE-588)4271255-5 gnd rswk-swf Pharmakogenetik (DE-588)4271255-5 s 1\p DE-604 Altman, Russ edt Flockhart, David A edt Goldstein, David B edt Erscheint auch als Druckausgabe 978-0-521-88537-9 https://doi.org/10.1017/CBO9781139051194 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Principles of pharmacogenetics and pharmacogenomics pt. I. Critical Concepts. Introduction to population diversity and genetic testing / James K. Burmester, Ingrid Glurich, Kimberly Pillsbury and Michael D. Caldwell -- Genotyping technologies / Sharon Marsh and Cristi R. King -- Pharmacokinetics: absorption, distribution, metabolism, excretion / Terry Blaschke -- Overview: adverse drug reactions / Matthew Nelson -- PharmGKB, a centralized resource for pharmacogenomic knowledge and discovery / Li Gong and Teri E. Klein -- DrugBank / David S. Wishart -- Ethical considerations for pharmacogenomics: privacy and confidentiality / Sandra Lee -- Informed consent in pharmacogenomic research and treatment / Mark Rothstein -- Legal trends driving the clinical translation of pharmacogenomics / Barbara Evans -- pt. II. Therapeutic Areas. Pharmacogenetics of oncologic drugs / Mark Ratain, Uchenna Njaju and Eileen Dolan -- Pharmacogenetics of cardiovascular drugs / Michael Stein and Danny Kurnik -- Pharmacogenomics of statin-induced muscle toxicity / Ronald M. Krauss, Russell A. Wilke, Melissa Antonik and Elenita Kanin -- Pharmacogenomics of the drug-induced long QT syndrome / Dan M. Roden, Prince J. Kannankeril, Stefan Kaab and Dawood Darbar -- Pharmacogenetics of diabetes drugs / O.H. Klungel and Mark C.H. DeGroot -- Pharmacogenetics of respiratory drugs / Kelan Tantisira and Scott Weiss -- Pharmacogenomics for acid-related gastrointestinal drugs / Takahisa Furuta -- Pharmacogenetics of rheumatoid arthritis drugs / Robert M. Plenge, Yvonne C. Lee, Souomya Raychaudhuri and Daniel H. Solomon -- Pharmacogenomics of obstetric drugs / David Haas and Jamie Renbarger -- Pharmacogenomics of psychiatric drugs / David Mrazek Pharmacogenomics of pain and anesthesia drugs / Evan Kharasch and Konrad Meissner -- Pharmacogenetics of HIV and antiretroviral drugs / Amalio Telenti -- Pharmacogenomics in pediatrics / Jennifer A. Lowry and J. Steven Leeder -- Pharmacogenomics in fetal and neonatal medicine / Yair Blumenfeld Pharmacogenetics Pharmakogenetik (DE-588)4271255-5 gnd |
| subject_GND | (DE-588)4271255-5 |
| title | Principles of pharmacogenetics and pharmacogenomics |
| title_alt | Principles of pharmacogenetics & pharmacogenomics |
| title_auth | Principles of pharmacogenetics and pharmacogenomics |
| title_exact_search | Principles of pharmacogenetics and pharmacogenomics |
| title_full | Principles of pharmacogenetics and pharmacogenomics edited by Russ B. Altman, David Flockhart, David B. Goldstein |
| title_fullStr | Principles of pharmacogenetics and pharmacogenomics edited by Russ B. Altman, David Flockhart, David B. Goldstein |
| title_full_unstemmed | Principles of pharmacogenetics and pharmacogenomics edited by Russ B. Altman, David Flockhart, David B. Goldstein |
| title_short | Principles of pharmacogenetics and pharmacogenomics |
| title_sort | principles of pharmacogenetics and pharmacogenomics |
| topic | Pharmacogenetics Pharmakogenetik (DE-588)4271255-5 gnd |
| topic_facet | Pharmacogenetics Pharmakogenetik |
| url | https://doi.org/10.1017/CBO9781139051194 |
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