Animal cells as bioreactors:
Because of their complexity, the new generation of genetically engineered protein drugs can only be made by biotechnological methods, using cultures of animal cells. This book covers all aspects of the technologies needed to turn animal cells into an acceptable and cost-effective tool for drug produ...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge University Press
1994
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| Schriftenreihe: | Cambridge studies in biotechnology
11 |
| Schlagworte: | |
| Online-Zugang: | BSB01 FHN01 Volltext |
| Zusammenfassung: | Because of their complexity, the new generation of genetically engineered protein drugs can only be made by biotechnological methods, using cultures of animal cells. This book covers all aspects of the technologies needed to turn animal cells into an acceptable and cost-effective tool for drug production. This includes modifying them genetically so that they produce the right product in high yield, getting them to grow reproducibly on an industrial scale, and extracting the required product from them. It also covers biological safety issues, and the verification of the chemical and biological nature of the protein drug produced. The work covers developments in all of these areas and how they all need to be integrated for the design of an effective biotechnological production process. It therefore provides a comprehensive guide to this area of biotechnology |
| Beschreibung: | Title from publisher's bibliographic system (viewed on 05 Oct 2015) |
| Beschreibung: | 1 online resource (v, 184 pages) |
| ISBN: | 9780511565069 |
| DOI: | 10.1017/CBO9780511565069 |
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| 505 | 8 | |a Introducing the animal cell as a bioreactor -- Yields of recombinant product: engineering cells for maximum expression -- Generation of biomass -- Adjusting cellular metabolism for optimum product yield -- Downstream processing -- Regulatory aspects of using cells as bioreactors | |
| 520 | |a Because of their complexity, the new generation of genetically engineered protein drugs can only be made by biotechnological methods, using cultures of animal cells. This book covers all aspects of the technologies needed to turn animal cells into an acceptable and cost-effective tool for drug production. This includes modifying them genetically so that they produce the right product in high yield, getting them to grow reproducibly on an industrial scale, and extracting the required product from them. It also covers biological safety issues, and the verification of the chemical and biological nature of the protein drug produced. The work covers developments in all of these areas and how they all need to be integrated for the design of an effective biotechnological production process. It therefore provides a comprehensive guide to this area of biotechnology | ||
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Datensatz im Suchindex
| _version_ | 1804176883991969792 |
|---|---|
| any_adam_object | |
| author | Cartwright, Terence |
| author_facet | Cartwright, Terence |
| author_role | aut |
| author_sort | Cartwright, Terence |
| author_variant | t c tc |
| building | Verbundindex |
| bvnumber | BV043941812 |
| classification_rvk | WF 9725 |
| collection | ZDB-20-CBO |
| contents | Introducing the animal cell as a bioreactor -- Yields of recombinant product: engineering cells for maximum expression -- Generation of biomass -- Adjusting cellular metabolism for optimum product yield -- Downstream processing -- Regulatory aspects of using cells as bioreactors |
| ctrlnum | (ZDB-20-CBO)CR9780511565069 (OCoLC)849880047 (DE-599)BVBBV043941812 |
| dewey-full | 615/.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.19 |
| dewey-search | 615/.19 |
| dewey-sort | 3615 219 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| doi_str_mv | 10.1017/CBO9780511565069 |
| format | Electronic eBook |
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| id | DE-604.BV043941812 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:39:16Z |
| institution | BVB |
| isbn | 9780511565069 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029350782 |
| oclc_num | 849880047 |
| open_access_boolean | |
| owner | DE-12 DE-92 |
| owner_facet | DE-12 DE-92 |
| physical | 1 online resource (v, 184 pages) |
| psigel | ZDB-20-CBO ZDB-20-CBO BSB_PDA_CBO ZDB-20-CBO FHN_PDA_CBO |
| publishDate | 1994 |
| publishDateSearch | 1994 |
| publishDateSort | 1994 |
| publisher | Cambridge University Press |
| record_format | marc |
| series2 | Cambridge studies in biotechnology |
| spelling | Cartwright, Terence Verfasser aut Animal cells as bioreactors Terence Cartwright Cambridge Cambridge University Press 1994 1 online resource (v, 184 pages) txt rdacontent c rdamedia cr rdacarrier Cambridge studies in biotechnology 11 Title from publisher's bibliographic system (viewed on 05 Oct 2015) Introducing the animal cell as a bioreactor -- Yields of recombinant product: engineering cells for maximum expression -- Generation of biomass -- Adjusting cellular metabolism for optimum product yield -- Downstream processing -- Regulatory aspects of using cells as bioreactors Because of their complexity, the new generation of genetically engineered protein drugs can only be made by biotechnological methods, using cultures of animal cells. This book covers all aspects of the technologies needed to turn animal cells into an acceptable and cost-effective tool for drug production. This includes modifying them genetically so that they produce the right product in high yield, getting them to grow reproducibly on an industrial scale, and extracting the required product from them. It also covers biological safety issues, and the verification of the chemical and biological nature of the protein drug produced. The work covers developments in all of these areas and how they all need to be integrated for the design of an effective biotechnological production process. It therefore provides a comprehensive guide to this area of biotechnology Animal cell biotechnology Pharmaceutical biotechnology Biotechnologie (DE-588)4069491-4 gnd rswk-swf Bioreaktor (DE-588)4006780-4 gnd rswk-swf Tierzelle (DE-588)4185509-7 gnd rswk-swf Biotechnologie (DE-588)4069491-4 s Tierzelle (DE-588)4185509-7 s 1\p DE-604 Bioreaktor (DE-588)4006780-4 s 2\p DE-604 Erscheint auch als Druckausgabe 978-0-521-10310-7 Erscheint auch als Druckausgabe 978-0-521-41258-2 https://doi.org/10.1017/CBO9780511565069 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Cartwright, Terence Animal cells as bioreactors Introducing the animal cell as a bioreactor -- Yields of recombinant product: engineering cells for maximum expression -- Generation of biomass -- Adjusting cellular metabolism for optimum product yield -- Downstream processing -- Regulatory aspects of using cells as bioreactors Animal cell biotechnology Pharmaceutical biotechnology Biotechnologie (DE-588)4069491-4 gnd Bioreaktor (DE-588)4006780-4 gnd Tierzelle (DE-588)4185509-7 gnd |
| subject_GND | (DE-588)4069491-4 (DE-588)4006780-4 (DE-588)4185509-7 |
| title | Animal cells as bioreactors |
| title_auth | Animal cells as bioreactors |
| title_exact_search | Animal cells as bioreactors |
| title_full | Animal cells as bioreactors Terence Cartwright |
| title_fullStr | Animal cells as bioreactors Terence Cartwright |
| title_full_unstemmed | Animal cells as bioreactors Terence Cartwright |
| title_short | Animal cells as bioreactors |
| title_sort | animal cells as bioreactors |
| topic | Animal cell biotechnology Pharmaceutical biotechnology Biotechnologie (DE-588)4069491-4 gnd Bioreaktor (DE-588)4006780-4 gnd Tierzelle (DE-588)4185509-7 gnd |
| topic_facet | Animal cell biotechnology Pharmaceutical biotechnology Biotechnologie Bioreaktor Tierzelle |
| url | https://doi.org/10.1017/CBO9780511565069 |
| work_keys_str_mv | AT cartwrightterence animalcellsasbioreactors |