Parkinson's disease: current and future therapeutics and clinical trials
Parkinson's disease is no longer considered only a motor disorder. It has become evident that the pathological changes are broad, the progression seems to follow a pattern suggesting transynaptic transmission via templation of proteins in a prion-like fashion, and that these pathological change...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2016
|
| Schriftenreihe: | Cambridge medicine
|
| Schlagworte: | |
| Online-Zugang: | BSB01 FHN01 Volltext |
| Zusammenfassung: | Parkinson's disease is no longer considered only a motor disorder. It has become evident that the pathological changes are broad, the progression seems to follow a pattern suggesting transynaptic transmission via templation of proteins in a prion-like fashion, and that these pathological changes usually antedate the motor symptoms by decades. This book emphasizes treatment options for Parkinson's disease, critically assessing pharmacologic and surgical interventions for all aspects of the disease. Evidence from randomized controlled clinical trials is highlighted to develop practical recommendations for clinical practice. Lessons learnt from clinical trials – and controversies and future challenges – are all addressed. Readers will find the necessary clinical and scientific foundations for the understanding of the disease, the underpinnings of the pathological processes, the identification of disease biomarkers, and the basis for solid therapeutics. Chapters are authored by an international team of specialists who bring their expertise to improving the management of this disease |
| Beschreibung: | Title from publisher's bibliographic system (viewed on 08 Mar 2016) |
| Beschreibung: | 1 online resource (xi, 367 pages) |
| ISBN: | 9781107284210 |
| DOI: | 10.1017/CBO9781107284210 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV043940329 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 161206s2016 |||| o||u| ||||||eng d | ||
| 020 | |a 9781107284210 |c Online |9 978-1-107-28421-0 | ||
| 024 | 7 | |a 10.1017/CBO9781107284210 |2 doi | |
| 035 | |a (ZDB-20-CBO)CR9781107284210 | ||
| 035 | |a (OCoLC)967758609 | ||
| 035 | |a (DE-599)BVBBV043940329 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-12 |a DE-92 | ||
| 082 | 0 | |a 616.83306 |2 23 | |
| 245 | 1 | 0 | |a Parkinson's disease |b current and future therapeutics and clinical trials |c edited by Néstor Gálvez-Jiménez [and three others] |
| 264 | 1 | |a Cambridge |b Cambridge University Press |c 2016 | |
| 300 | |a 1 online resource (xi, 367 pages) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Cambridge medicine | |
| 500 | |a Title from publisher's bibliographic system (viewed on 08 Mar 2016) | ||
| 520 | |a Parkinson's disease is no longer considered only a motor disorder. It has become evident that the pathological changes are broad, the progression seems to follow a pattern suggesting transynaptic transmission via templation of proteins in a prion-like fashion, and that these pathological changes usually antedate the motor symptoms by decades. This book emphasizes treatment options for Parkinson's disease, critically assessing pharmacologic and surgical interventions for all aspects of the disease. Evidence from randomized controlled clinical trials is highlighted to develop practical recommendations for clinical practice. Lessons learnt from clinical trials – and controversies and future challenges – are all addressed. Readers will find the necessary clinical and scientific foundations for the understanding of the disease, the underpinnings of the pathological processes, the identification of disease biomarkers, and the basis for solid therapeutics. Chapters are authored by an international team of specialists who bring their expertise to improving the management of this disease | ||
| 650 | 4 | |a Parkinson's disease / Treatment | |
| 700 | 1 | |a Gálvez-Jiménez, Néstor |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druckausgabe |z 978-1-107-05386-1 |
| 856 | 4 | 0 | |u https://doi.org/10.1017/CBO9781107284210 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-20-CBO | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-029349299 | ||
| 966 | e | |u https://doi.org/10.1017/CBO9781107284210 |l BSB01 |p ZDB-20-CBO |q BSB_PDA_CBO |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1017/CBO9781107284210 |l FHN01 |p ZDB-20-CBO |q FHN_PDA_CBO |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804176880730898432 |
|---|---|
| any_adam_object | |
| author2 | Gálvez-Jiménez, Néstor |
| author2_role | edt |
| author2_variant | n g j ngj |
| author_facet | Gálvez-Jiménez, Néstor |
| building | Verbundindex |
| bvnumber | BV043940329 |
| collection | ZDB-20-CBO |
| ctrlnum | (ZDB-20-CBO)CR9781107284210 (OCoLC)967758609 (DE-599)BVBBV043940329 |
| dewey-full | 616.83306 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.83306 |
| dewey-search | 616.83306 |
| dewey-sort | 3616.83306 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1017/CBO9781107284210 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02652nmm a2200397zc 4500</leader><controlfield tag="001">BV043940329</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">161206s2016 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781107284210</subfield><subfield code="c">Online</subfield><subfield code="9">978-1-107-28421-0</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1017/CBO9781107284210</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-20-CBO)CR9781107284210</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)967758609</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043940329</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-12</subfield><subfield code="a">DE-92</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.83306</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Parkinson's disease</subfield><subfield code="b">current and future therapeutics and clinical trials</subfield><subfield code="c">edited by Néstor Gálvez-Jiménez [and three others]</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Cambridge</subfield><subfield code="b">Cambridge University Press</subfield><subfield code="c">2016</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (xi, 367 pages)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Cambridge medicine</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Title from publisher's bibliographic system (viewed on 08 Mar 2016)</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Parkinson's disease is no longer considered only a motor disorder. It has become evident that the pathological changes are broad, the progression seems to follow a pattern suggesting transynaptic transmission via templation of proteins in a prion-like fashion, and that these pathological changes usually antedate the motor symptoms by decades. This book emphasizes treatment options for Parkinson's disease, critically assessing pharmacologic and surgical interventions for all aspects of the disease. Evidence from randomized controlled clinical trials is highlighted to develop practical recommendations for clinical practice. Lessons learnt from clinical trials – and controversies and future challenges – are all addressed. Readers will find the necessary clinical and scientific foundations for the understanding of the disease, the underpinnings of the pathological processes, the identification of disease biomarkers, and the basis for solid therapeutics. Chapters are authored by an international team of specialists who bring their expertise to improving the management of this disease</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Parkinson's disease / Treatment</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gálvez-Jiménez, Néstor</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druckausgabe</subfield><subfield code="z">978-1-107-05386-1</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1017/CBO9781107284210</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-20-CBO</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-029349299</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1017/CBO9781107284210</subfield><subfield code="l">BSB01</subfield><subfield code="p">ZDB-20-CBO</subfield><subfield code="q">BSB_PDA_CBO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1017/CBO9781107284210</subfield><subfield code="l">FHN01</subfield><subfield code="p">ZDB-20-CBO</subfield><subfield code="q">FHN_PDA_CBO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV043940329 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:39:13Z |
| institution | BVB |
| isbn | 9781107284210 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029349299 |
| oclc_num | 967758609 |
| open_access_boolean | |
| owner | DE-12 DE-92 |
| owner_facet | DE-12 DE-92 |
| physical | 1 online resource (xi, 367 pages) |
| psigel | ZDB-20-CBO ZDB-20-CBO BSB_PDA_CBO ZDB-20-CBO FHN_PDA_CBO |
| publishDate | 2016 |
| publishDateSearch | 2016 |
| publishDateSort | 2016 |
| publisher | Cambridge University Press |
| record_format | marc |
| series2 | Cambridge medicine |
| spelling | Parkinson's disease current and future therapeutics and clinical trials edited by Néstor Gálvez-Jiménez [and three others] Cambridge Cambridge University Press 2016 1 online resource (xi, 367 pages) txt rdacontent c rdamedia cr rdacarrier Cambridge medicine Title from publisher's bibliographic system (viewed on 08 Mar 2016) Parkinson's disease is no longer considered only a motor disorder. It has become evident that the pathological changes are broad, the progression seems to follow a pattern suggesting transynaptic transmission via templation of proteins in a prion-like fashion, and that these pathological changes usually antedate the motor symptoms by decades. This book emphasizes treatment options for Parkinson's disease, critically assessing pharmacologic and surgical interventions for all aspects of the disease. Evidence from randomized controlled clinical trials is highlighted to develop practical recommendations for clinical practice. Lessons learnt from clinical trials – and controversies and future challenges – are all addressed. Readers will find the necessary clinical and scientific foundations for the understanding of the disease, the underpinnings of the pathological processes, the identification of disease biomarkers, and the basis for solid therapeutics. Chapters are authored by an international team of specialists who bring their expertise to improving the management of this disease Parkinson's disease / Treatment Gálvez-Jiménez, Néstor edt Erscheint auch als Druckausgabe 978-1-107-05386-1 https://doi.org/10.1017/CBO9781107284210 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Parkinson's disease current and future therapeutics and clinical trials Parkinson's disease / Treatment |
| title | Parkinson's disease current and future therapeutics and clinical trials |
| title_auth | Parkinson's disease current and future therapeutics and clinical trials |
| title_exact_search | Parkinson's disease current and future therapeutics and clinical trials |
| title_full | Parkinson's disease current and future therapeutics and clinical trials edited by Néstor Gálvez-Jiménez [and three others] |
| title_fullStr | Parkinson's disease current and future therapeutics and clinical trials edited by Néstor Gálvez-Jiménez [and three others] |
| title_full_unstemmed | Parkinson's disease current and future therapeutics and clinical trials edited by Néstor Gálvez-Jiménez [and three others] |
| title_short | Parkinson's disease |
| title_sort | parkinson s disease current and future therapeutics and clinical trials |
| title_sub | current and future therapeutics and clinical trials |
| topic | Parkinson's disease / Treatment |
| topic_facet | Parkinson's disease / Treatment |
| url | https://doi.org/10.1017/CBO9781107284210 |
| work_keys_str_mv | AT galvezjimeneznestor parkinsonsdiseasecurrentandfuturetherapeuticsandclinicaltrials |