DNA microarrays:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier/Academic Press
©2006
|
| Schriftenreihe: | Methods in enzymology
v. 410-411 |
| Schlagworte: | |
| Online-Zugang: | UER01 FAW01 Volltext |
| Beschreibung: | Includes bibliographical references and indexes Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. Provides an overview of platforms Includes experimental design and wet bench protocols Presents statistical and data analysis methods, array databases, data visualization and meta analysis |
| Beschreibung: | 2 volumes |
| ISBN: | 0080464653 9780080464657 0121828158 9780121828158 |
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| indexdate | 2024-07-10T07:37:28Z |
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| isbn | 0080464653 9780080464657 0121828158 9780121828158 |
| language | English |
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| series2 | Methods in enzymology |
| spelling | DNA microarrays edited by Alan Kimmel & Brian Oliver Amsterdam Elsevier/Academic Press ©2006 2 volumes txt rdacontent c rdamedia cr rdacarrier Methods in enzymology v. 410-411 Includes bibliographical references and indexes Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. Provides an overview of platforms Includes experimental design and wet bench protocols Presents statistical and data analysis methods, array databases, data visualization and meta analysis Oligonucleotide Array Sequence Analysis / methods DNA. Gene Expression Profiling / methods DNA. fast DNA microarrays fast DNA microarrays Kimmel, Alan R. Sonstige oth Oliver, Brian Sonstige oth http://www.sciencedirect.com/science/book/9780121828158 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | DNA microarrays Oligonucleotide Array Sequence Analysis / methods DNA. Gene Expression Profiling / methods DNA. fast DNA microarrays fast DNA microarrays |
| title | DNA microarrays |
| title_auth | DNA microarrays |
| title_exact_search | DNA microarrays |
| title_full | DNA microarrays edited by Alan Kimmel & Brian Oliver |
| title_fullStr | DNA microarrays edited by Alan Kimmel & Brian Oliver |
| title_full_unstemmed | DNA microarrays edited by Alan Kimmel & Brian Oliver |
| title_short | DNA microarrays |
| title_sort | dna microarrays |
| topic | Oligonucleotide Array Sequence Analysis / methods DNA. Gene Expression Profiling / methods DNA. fast DNA microarrays fast DNA microarrays |
| topic_facet | Oligonucleotide Array Sequence Analysis / methods DNA. Gene Expression Profiling / methods DNA microarrays |
| url | http://www.sciencedirect.com/science/book/9780121828158 |
| work_keys_str_mv | AT kimmelalanr dnamicroarrays AT oliverbrian dnamicroarrays |