DNA microarrays, Volume 411, Part B:
Gespeichert in:
Format: | Elektronisch E-Book |
---|---|
Sprache: | English |
Veröffentlicht: |
Amsterdam
Elsevier/Academic Press
©2006
|
Schriftenreihe: | Methods in enzymology
volume 411, pt. B. |
Schlagworte: | |
Online-Zugang: | UER01 FAW01 URL des Erstveröffentlichers |
Beschreibung: | Includes bibliographical references and indexes Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. Provides an overview of platforms Includes experimental design and wet bench protocols. Presents statistical and data analysis methods, array databases, data visualization and meta analysis |
Beschreibung: | xxxvi, 469 |
ISBN: | 9780080464664 0080464661 0121828166 9780121828165 |
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series2 | Methods in enzymology |
spelling | DNA microarrays, Volume 411, Part B edited by Alan Kimmel & Brian Oliver Databases and statistics Amsterdam Elsevier/Academic Press ©2006 xxxvi, 469 txt rdacontent c rdamedia cr rdacarrier Methods in enzymology volume 411, pt. B. Includes bibliographical references and indexes Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. Provides an overview of platforms Includes experimental design and wet bench protocols. Presents statistical and data analysis methods, array databases, data visualization and meta analysis Oligonucleotide Array Sequence Analysis / methods Oligonucleotide Array Sequence Analysis / statistics & numerical data Gene Expression Profiling / methods SCIENCE / Life Sciences / Biochemistry bisacsh DNA. fast DNA microarrays fast DNA microarrays DNA. Kimmel, Alan R. Sonstige oth Oliver, Brian Sonstige oth http://www.sciencedirect.com/science/book/9780121828165 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | DNA microarrays, Volume 411, Part B Oligonucleotide Array Sequence Analysis / methods Oligonucleotide Array Sequence Analysis / statistics & numerical data Gene Expression Profiling / methods SCIENCE / Life Sciences / Biochemistry bisacsh DNA. fast DNA microarrays fast DNA microarrays DNA. |
title | DNA microarrays, Volume 411, Part B |
title_alt | Databases and statistics |
title_auth | DNA microarrays, Volume 411, Part B |
title_exact_search | DNA microarrays, Volume 411, Part B |
title_full | DNA microarrays, Volume 411, Part B edited by Alan Kimmel & Brian Oliver |
title_fullStr | DNA microarrays, Volume 411, Part B edited by Alan Kimmel & Brian Oliver |
title_full_unstemmed | DNA microarrays, Volume 411, Part B edited by Alan Kimmel & Brian Oliver |
title_short | DNA microarrays, Volume 411, Part B |
title_sort | dna microarrays volume 411 part b |
topic | Oligonucleotide Array Sequence Analysis / methods Oligonucleotide Array Sequence Analysis / statistics & numerical data Gene Expression Profiling / methods SCIENCE / Life Sciences / Biochemistry bisacsh DNA. fast DNA microarrays fast DNA microarrays DNA. |
topic_facet | Oligonucleotide Array Sequence Analysis / methods Oligonucleotide Array Sequence Analysis / statistics & numerical data Gene Expression Profiling / methods SCIENCE / Life Sciences / Biochemistry DNA. DNA microarrays |
url | http://www.sciencedirect.com/science/book/9780121828165 |
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