RNA turnover in eukaryotes, Volume 449: analysis of specialized and quality control RNA decay pathways
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Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: San Diego, Calif. Academic 2008
Schriftenreihe:Methods in enzymology volume 449
Schlagworte:
Online-Zugang:UER01
FAW01
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Beschreibung:Includes bibliographical references and indexes
Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. * Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway * Expert researchers introduce the most advanced technologies and techniques * Offers step-by-step lab instructions, including necessary equipment and reagents
Beschreibung:xliv, 417 p., [1] leaf of plates
ISBN:9780080923321
0080923321
9780123745842
0123745845
9780123743787

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