Landmark papers in rheumatology:
There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century. This book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rh...
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| Weitere Verfasser: | , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
[Oxford]
Oxford University Press
2015
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext Inhaltsverzeichnis |
| Zusammenfassung: | There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century. This book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic disease |
| ISBN: | 9780191767616 |
| DOI: | 10.1093/med/9780199688371.001.0001 |
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| 245 | 1 | 0 | |a Landmark papers in rheumatology |c edited by Richard A. Watts and David G. I. Scott |
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| 520 | |a There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century. This book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic disease | ||
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Datensatz im Suchindex
| _version_ | 1804176713818570752 |
|---|---|
| adam_text | Titel: Landmark papers in rheumatology
Autor: Watts, Richard
Jahr: 2015
Contents
Contributors xv
1 Epidemiology and genetics 1
James Bluett, Suzanne Verstappen, and Deborah Symmons
Introduction 1
Paper 1.1: Radiological assessment of osteoarthritis—the Kellgren and Lawrence
score 4
Paper 1.2: The association between rheumatoid arthritis and lymphoma 7
Paper 1.3: The American Rheumatism Association 1987 revised criteria for the
classification of rheumatoid arthritis 10
Paper 1.4: The global burden of disease 15
Paper 1.5: The shared epitope hypothesis 19
Paper 1.6: The association between protein tyrosine phosphatase 22 and rheumatoid
arthritis 23
Paper 1.7: The Wellcome Trust genome-wide association study of rheumatoid
arthritis 25
Paper 1.8: Five amino acids in three proteins encoded by MHC genes explain most
of the association between the MHC locus and seropositive rheumatoid
arthritis 27
Paper 1.9: High-density genetic mapping identifies new susceptibility loci for
rheumatoid arthritis 30
Paper 1.10: Gene-environment interaction in the aetiology of rheumatoid arthritis 32
2 Rheumatoid arthritis 37
Elena Nikiphorou and Adam Young
Introduction 37
Landmark paper selection 38
Paper 2.1: Rheumatoid arthritis in a population sample 39
Paper 2.2: Judging disease activity in clinical practice in rheumatoid arthritis: first
steps in the development of a disease activity score 42
Paper 2.3: Measurement of patient outcome in rheumatoid arthritis 48
Paper 2 .4: Effects of cortisone acetate and pituitary adrenocorticotropic hormone on
rheumatoid arthritis, rheumatic fever, and certain other conditions 53
Paper 2.5: Efficacy of low-dose methotrexate in rheumatoid arthritis 56
Paper 2.6: Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal
antibody) versus placebo in rheumatoid arthritis patients receiving
concomitant methotrexate: a randomized phase III trial 59
Paper 2.7: Taking mortality in rheumatoid arthritis seriously—predictive markers,
socio-economic status, and co-morbidity 62
X CONTENTS
Paper 2.8: Rheumatoid arthritis: treatment which controls the C-reactive protein
and erythrocyte sedimentation rate reduces radiological progression 65
Paper 2.9: Effect of a treatment strategy of tight control for rheumatoid arthritis
(the TICORA study): a single-blind randomized controlled trial 68
Paper 2.10: Clinical and radiographic outcomes of four different treatment strategies
in patients with early rheumatoid arthritis (the BeSt study): a randomized,
controlled trial 73
3 Spondyloarthropathies 77
Carmel Stober and Hill Gaston
Introduction 77
Paper 3.1: Recognition of psoriatic arthritis 79
Paper 3.2: Associations between ankylosing spondylitis, psoriatic arthritis, Reiter s
disease, the intestinal arthropathies, and Behcet s syndrome 83
Paper 3.3: The discovery of the association between ankylosing spondylitis and
HLA-B27 88
Paper 3.4: A syndrome of seronegative enthesopathy and arthropathy in children 91
Paper 3.5: Yersinia antigens in synovial-fluid cells from patients with reactive
arthritis 95
Paper 3.6: Transgenic expression of HLA-B27 in rats induces various inflammatory
disorders with clear links to spondyloarthritis 98
Paper 3 .7: The evolution of spondyloarthropathies in relation to gut histology 103
Paper 3.8: A hypothesis that enthesitis is the primary pathological process occurring
in spondylarthropathy 108
Paper 3.9: First, and dramatic, indication ofthe effectiveness of tumour necrosis
factor a blockade in ankylosing spondylitis 113
Paper 3.10: Additional genes which influence susceptibility to ankylosing spondylitis,
including ERAP1, which affects HLA-B27 assembly 117
4 Systemic lupus erythematosus 121
Benjamin Parker and lan N. Bruce
Introduction 121
Paper 4.1: Common overlapping pathological features of systemic autoimmune
rheumatic diseases 122
Paper 4.2: The LE cell phenomenon 125
Paper 4.3: Complement deposition demonstrated in systemic lupus erythematosus
tissue 128
Paper 4.4: Premature cardiovascular disease in systemic lupus erythematosus
patients 131
Paper 4.5: Long-term trials demonstrate the efficacy of immunosuppression for lupus
nephritis 135
Paper 4.6: Development of classification criteria for systemic lupus erythematosus 139
Paper 4.7: Interferon implicated in immunopathogenesis of systemic lupus
erythematosus 142
Paper 4.8: Successful clinical trials of belimumab in systemic lupus erythematosus 144
CONTENTS I xi
Paper 4.9: The first description of the association between the lupus anticoagulant
and thrombosis in systemic lupus erythematosus 147
Paper 4.10: The impact of withdrawal of hydroxychloroquine in stable systemic lupus
erythematosus 150
5 Vasculitis 153
Haroon Khan, David G. I. Scott, and Richard A. Watts
Introduction 153
Paper 5.1: Earliest description of systemic vasculitis 155
Paper 5.2: Pathology of giant cell arteritis 157
Paper 5.3: Original description of Kawasaki disease 160
Paper 5.4: Relationship between infection with hepatitis B virus and polyarteritis
nodosa 164
Paper 5.5: The discovery of anti-neutrophil cytoplasmic antibodies as a marker
of Wegener s granulomatosis 167
Paper 5.6: Definitions and nomenclature of vasculitis—the Chapel Hill Consensus
Conferences, 1994 and 2012 170
Paper 5.7: Development of assessment tools for systemic vasculitis 176
Paper 5.8: Cyclophosphamide as treatment for systemic vasculitis 179
Paper 5.9: Maintenance therapy for systemic vasculitis 181
Paper 5.10: Biologic therapy for systemic vasculitis 184
6 Osteoarthritis 189
Iain Goff and Fraser Birrell
Introduction 189
Paper 6.1: The first description of nodal osteoarthritis 191
Paper 6.2: Arthroplasty of the hip 193
Paper 6.3: Prevalence of symptoms and structural changes of osteoarthritis in the
population 197
Paper 6.4: Effect of age on the prevalence of osteoarthritis 201
Paper 6.5: Predicting progression of osteoarthritis using imaging 205
Paper 6.6: Aerobic exercise and resistance exercise versus an education programme
in knee osteoarthritis 207
Paper 6.7: Glucosamine sulphate for symptoms and progression of knee
osteoarthritis 210
Paper 6.8: Arthroscopy versus sham arthroscopy in knee osteoarthritis 214
Paper 6.9: Association of pain and radiographic change 216
Paper 6.10: Efficacy and toxicity of paracetamol 219
7 Gout and crystal arthropathies 223
Lorna Clarson and Edward Roddy
Introduction 223
Paper 7.1: Identification of urate crystals in gouty synovial fluid 227
Paper 7.2: Molecular identification of a renal urate anion exchanger that regulates
blood urate levels 230
Xii | CONTENTS
Paper 7.3: Gout-associated uric acid crystals activate the NALP3 inflammasome 234
Paper 7.4: Dietary risk factors for gout 237
Paper 7.5: Gout and coronary heart disease: the Framingham Study 242
Paper 7.6: Allopurinol therapy for gout 246
Paper 7.7: Febuxostat compared with allopurinol in patients with hyperuricemia
and gout 251
Paper 7.8: Can acute attacks of gout be prevented by optimum suppression
of urate? 255
Paper 7.9: Mutations in ANKH cause Chondrocalcinosis 258
Paper 7.10: Clinical and radiographic features of pyrophosphate arthropathy 263
8 Paediatric rheumatology 269
Nicola Ambrose, Despina Eleftheriou, and John loannou
Introduction 269
Paper 8.1: Comparison of cortisone and aspirin in treatment of juvenile rheumatoid
arthritis 271
Paper 8.2: The treatment of Kawasaki syndrome with intravenous gamma
globulin 274
Paper 8.3: Intra-articular triamcinolone hexacetonide in the management of chronic
arthritis in children 278
Paper 8.4: A USA-USSR double-blind, placebo-controlled trial on methotrexate
in resistant juvenile rheumatoid arthritis 281
Paper 8.5: Preliminary definition of improvement in juvenile arthritis 285
Paper 8.6: Autologous haemopoietic stem-cell transplantation in refractory juvenile
chronic arthritis 288
Paper 8.7: Etanercept in children with polyarticular juvenile rheumatoid arthritis 291
Paper 8.8: Classification of juvenile idiopathic arthritis: second revision, Edmonton,
2001 295
Paper 8.9: Randomized trial of tocilizumab in systemic juvenile idiopathic
arthritis 298
Paper 8.10: Adolescents with chronic disease: transition to adult health care 302
9 Metabolic bone disease 305
Ashok Bhalla and Tehseen Ahmed
Introduction 305
Paper 9.1: Epidemiology of osteoporotic fracture 307
Paper 9.2: Calcium and vitamin D in the prevention offractures 310
Paper 9.3: Alendronate and reduction of clinical vertebral fractures 313
Paper 9.4: Anabolic therapy in the treatment of osteoporosis 317
Paper 9.5: Atypical femoral fractures 320
Paper 9.6: Bisphosphonates and osteonecrosis of the jaw 325
Paper 9.7: Treatment of Pagets disease of bone 329
Paper 9 .8: Mechanisms of altered calcium homeostasis in sarcoidosis 332
CONTENTS xiii
10 Ehlers-Danlos syndrome and Marfan Syndrome 335
Alan Hakim and Asma Fikree
Introduction 335
Paper 10.1: The clinical and genetic description of Ehlers-Danlos syndrome
as an inherited trait 341
Paper 10.2: Heterogeneity and the classification of Ehlers-Danlos syndrome 343
Paper 10.3: Collagen defects, and genetic linkage in Ehlers-Danlos syndrome 345
Paper 10.4: Genetic linkage in classical Ehlers-Danlos syndrome 347
Paper 10.5: Cardiovascular pathology and Marfan syndrome 349
Paper 10.6: Vascular surgery in Marfan syndrome 351
Paper 10.7: Connective tissue fragility—clinical evidence of the role of transforming
growth factor ß in Marfan syndrome 353
Summary 355
Index 357
|
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| spelling | Landmark papers in rheumatology edited by Richard A. Watts and David G. I. Scott [Oxford] Oxford University Press 2015 txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century. This book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic disease Rheumatology Watts, Richard edt Scott, David G. I. edt Erscheint auch als Druckausgabe 978-0-19-968837-1 https://doi.org/10.1093/med/9780199688371.001.0001 Verlag URL des Erstveröffentlichers Volltext HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029255360&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Landmark papers in rheumatology Includes bibliographical references and index Rheumatology |
| title | Landmark papers in rheumatology |
| title_auth | Landmark papers in rheumatology |
| title_exact_search | Landmark papers in rheumatology |
| title_full | Landmark papers in rheumatology edited by Richard A. Watts and David G. I. Scott |
| title_fullStr | Landmark papers in rheumatology edited by Richard A. Watts and David G. I. Scott |
| title_full_unstemmed | Landmark papers in rheumatology edited by Richard A. Watts and David G. I. Scott |
| title_short | Landmark papers in rheumatology |
| title_sort | landmark papers in rheumatology |
| topic | Rheumatology |
| topic_facet | Rheumatology |
| url | https://doi.org/10.1093/med/9780199688371.001.0001 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029255360&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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