Epigenetic Gene Expression and Regulation:
Epigenetic Gene Expression and Regulationreviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
s.l.
Elsevier Science
2015
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| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | Epigenetic Gene Expression and Regulationreviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapiesHelps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspringChapters are replete with clinical examples to empower the basic biology with translational significanceOffers more than 100 illustrations to distill key concepts and decipher complex science |
| Beschreibung: | Description based upon print version of record |
| ISBN: | 9780127999586 |
Internformat
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| 520 | 1 | |a Epigenetic Gene Expression and Regulationreviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapiesHelps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspringChapters are replete with clinical examples to empower the basic biology with translational significanceOffers more than 100 illustrations to distill key concepts and decipher complex science | |
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Datensatz im Suchindex
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| author | Huang, Suming |
| author_GND | (DE-588)1099709199 |
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| author_sort | Huang, Suming |
| author_variant | s h sh |
| building | Verbundindex |
| bvnumber | BV043799524 |
| collection | ZDB-33-ESD ebook ZDB-33-EBS |
| ctrlnum | (OCoLC)959667755 (DE-599)GBV839067321 |
| format | Electronic eBook |
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| id | DE-604.BV043799524 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:35:29Z |
| institution | BVB |
| isbn | 9780127999586 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029210909 |
| oclc_num | 959667755 |
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| publishDate | 2015 |
| publishDateSearch | 2015 |
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| publisher | Elsevier Science |
| record_format | marc |
| spelling | Huang, Suming Verfasser (DE-588)1099709199 aut Epigenetic Gene Expression and Regulation s.l. Elsevier Science 2015 txt rdacontent c rdamedia cr rdacarrier Description based upon print version of record Epigenetic Gene Expression and Regulationreviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapiesHelps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspringChapters are replete with clinical examples to empower the basic biology with translational significanceOffers more than 100 illustrations to distill key concepts and decipher complex science Online-Ausgabe Online-Ressource (484 p) Gene expression Epigenetics Genetic regulation Genexpression (DE-588)4020136-3 gnd rswk-swf Epigenetik (DE-588)7566079-9 gnd rswk-swf Genregulation (DE-588)4122166-7 gnd rswk-swf Electronic books Epigenetik (DE-588)7566079-9 s Genexpression (DE-588)4020136-3 s Genregulation (DE-588)4122166-7 s 1\p DE-604 Litt, Michael D. Sonstige oth Blakey, C. Ann Sonstige oth Reproduktion von Huang, Suming Epigenetic Gene Expression and Regulation 2015 http://www.sciencedirect.com/science/book/9780127999586 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Huang, Suming Epigenetic Gene Expression and Regulation Gene expression Epigenetics Genetic regulation Genexpression (DE-588)4020136-3 gnd Epigenetik (DE-588)7566079-9 gnd Genregulation (DE-588)4122166-7 gnd |
| subject_GND | (DE-588)4020136-3 (DE-588)7566079-9 (DE-588)4122166-7 |
| title | Epigenetic Gene Expression and Regulation |
| title_auth | Epigenetic Gene Expression and Regulation |
| title_exact_search | Epigenetic Gene Expression and Regulation |
| title_full | Epigenetic Gene Expression and Regulation |
| title_fullStr | Epigenetic Gene Expression and Regulation |
| title_full_unstemmed | Epigenetic Gene Expression and Regulation |
| title_short | Epigenetic Gene Expression and Regulation |
| title_sort | epigenetic gene expression and regulation |
| topic | Gene expression Epigenetics Genetic regulation Genexpression (DE-588)4020136-3 gnd Epigenetik (DE-588)7566079-9 gnd Genregulation (DE-588)4122166-7 gnd |
| topic_facet | Gene expression Epigenetics Genetic regulation Genexpression Epigenetik Genregulation |
| url | http://www.sciencedirect.com/science/book/9780127999586 |
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