Impedimetric biosensors for medical applications: current progress and challenges
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
ASME Press
[2013]
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| Schriftenreihe: | Biomedical & nanomedical technologies
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| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 |
| Beschreibung: | Includes bibliographical references (pages 57-70) 1. Introduction and scope 2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary 3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces 5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation 6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules 7. Conclusions and future perspectives 8. Author biographies -- References In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors |
| Beschreibung: | 70 pages |
| ISBN: | 9781606506370 1606506374 9781606506363 9780791860243 0791860248 1606506366 |
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| 500 | |a 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces | ||
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| 500 | |a In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors | ||
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| spelling | Rushworth, Jo V. Verfasser aut Impedimetric biosensors for medical applications current progress and challenges Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner New York, NY ASME Press [2013] 70 pages txt rdacontent c rdamedia cr rdacarrier Biomedical & nanomedical technologies Includes bibliographical references (pages 57-70) 1. Introduction and scope 2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary 3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data 4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces 5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation 6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules 7. Conclusions and future perspectives 8. Author biographies -- References In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors Biosensing Techniques Electric Impedance Biosensors Impedance spectroscopy HEALTH & FITNESS / Holism bisacsh HEALTH & FITNESS / Reference bisacsh MEDICAL / Alternative Medicine bisacsh MEDICAL / Atlases bisacsh MEDICAL / Essays bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Holistic Medicine bisacsh MEDICAL / Osteopathy bisacsh Biosensors fast Impedance spectroscopy fast Medizin Biosensor (DE-588)4193016-2 gnd rswk-swf Biosensor (DE-588)4193016-2 s 1\p DE-604 Hirst, Natalie A. Sonstige oth Goode, Jack A. Sonstige oth Pike, Douglas J. Sonstige oth Ahmed, Asif Sonstige oth Millner, Paul A. Sonstige oth 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Rushworth, Jo V. Impedimetric biosensors for medical applications current progress and challenges Biosensing Techniques Electric Impedance Biosensors Impedance spectroscopy HEALTH & FITNESS / Holism bisacsh HEALTH & FITNESS / Reference bisacsh MEDICAL / Alternative Medicine bisacsh MEDICAL / Atlases bisacsh MEDICAL / Essays bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Holistic Medicine bisacsh MEDICAL / Osteopathy bisacsh Biosensors fast Impedance spectroscopy fast Medizin Biosensor (DE-588)4193016-2 gnd |
| subject_GND | (DE-588)4193016-2 |
| title | Impedimetric biosensors for medical applications current progress and challenges |
| title_auth | Impedimetric biosensors for medical applications current progress and challenges |
| title_exact_search | Impedimetric biosensors for medical applications current progress and challenges |
| title_full | Impedimetric biosensors for medical applications current progress and challenges Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner |
| title_fullStr | Impedimetric biosensors for medical applications current progress and challenges Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner |
| title_full_unstemmed | Impedimetric biosensors for medical applications current progress and challenges Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner |
| title_short | Impedimetric biosensors for medical applications |
| title_sort | impedimetric biosensors for medical applications current progress and challenges |
| title_sub | current progress and challenges |
| topic | Biosensing Techniques Electric Impedance Biosensors Impedance spectroscopy HEALTH & FITNESS / Holism bisacsh HEALTH & FITNESS / Reference bisacsh MEDICAL / Alternative Medicine bisacsh MEDICAL / Atlases bisacsh MEDICAL / Essays bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Holistic Medicine bisacsh MEDICAL / Osteopathy bisacsh Biosensors fast Impedance spectroscopy fast Medizin Biosensor (DE-588)4193016-2 gnd |
| topic_facet | Biosensing Techniques Electric Impedance Biosensors Impedance spectroscopy HEALTH & FITNESS / Holism HEALTH & FITNESS / Reference MEDICAL / Alternative Medicine MEDICAL / Atlases MEDICAL / Essays MEDICAL / Family & General Practice MEDICAL / Holistic Medicine MEDICAL / Osteopathy Medizin Biosensor |
| work_keys_str_mv | AT rushworthjov impedimetricbiosensorsformedicalapplicationscurrentprogressandchallenges AT hirstnataliea impedimetricbiosensorsformedicalapplicationscurrentprogressandchallenges AT goodejacka impedimetricbiosensorsformedicalapplicationscurrentprogressandchallenges AT pikedouglasj impedimetricbiosensorsformedicalapplicationscurrentprogressandchallenges AT ahmedasif impedimetricbiosensorsformedicalapplicationscurrentprogressandchallenges AT millnerpaula impedimetricbiosensorsformedicalapplicationscurrentprogressandchallenges |