21st century genetics: genes at work
Gespeichert in:
Weitere Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Cold Spring Harbor, NY
Cold Spring Harbor Laboratory Press
2015
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Schriftenreihe: | Cold Spring Harbor Symposia on Quantitative Biology
80 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis Inhaltsverzeichnis |
Beschreibung: | xix, 361 Seiten Illustrationen, Diagramme 28 cm |
ISBN: | 9781621821472 9781621821274 |
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Datensatz im Suchindex
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adam_text | Contents
Symposium Participants v
Foreword xv
Gene Control
Imaging Transcription: Past, Present, and Future Robert A Coleman, Zhe Liu, Xavier Darzacq, 1
Robert Tjian, Robert H Singer, and Timothee Lionnet
Visualizing the HoxD Gene Cluster at the Nanoscale Level Pierre J Fabre, Alexander Benke, 9
Suliana Manley, and Denis Duboule
Transcriptional Enhancers: Bridging the Genome and Phenome Bing Ren and Feng Yue 17
Regulatory Principles Governing Tissue Specificity of Developmental Enhancers Emma K 27
Farley, Katrina M Olson, and Michael S Levine
The Importance of Controlling Transcription Elongation at Coding and Noncoding RNA Loci 33
Benjamin S Scruggs and Karen Adelman
Chromatin Domains and Nuclear Position
Regulatory Domains and Their Mechanisms Nezha S Benabdallah and Wendy A Bickmore 45
Large-Scale Chromatin Structure-Function Relationships during the Cell Cycle and Develop- 53
ment: Insights from Replication Timing Vishnu Dileep, Juan Carlos Rivera-Mulia, Jiao
Sima, and David M Gilbert
Prenucleosomes and Active Chromatin Mai T Khuong, Jia Fei, Haruhiko Ishii, and 65
James T Kadonaga
HIPMap: A High-Throughput Imaging Method for Mapping Spatial Gene Positions Si gal 73
Shachar, Gianluca Pegoraro, and Tom Misteli
Genome Organization and Chromosome Architecture Giorgio Bernardi 83
Genome Stability
A System to Study Aneuploidy In Vivo Sarah J Pfau and Angelika Amon 93
Resolution of Recombination Intermediates: Mechanisms and Regulation Stephen C West, 103
Miguel G Blanco, Ying Wai Chan, Joao Matos, Shriparna Sarbajna, and Haley D M Wyatt
21st Century Genetics: Mass Spectrometry of Yeast Telomerase Kah Wai Lin and 111
Virginia A Zakian
From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes 117
Cheng-Zhong Zhang and David Pellman
The Evolution of Tumors in Mice and Humans with Germline p53 Mutations Arnold J Levine, 139
Chang S Chan, Crissy Dudgeon, Anna Puzio-Kuter, and Pierre Hainaut
Germ Cells and Early Development
Mechanism and Reconstitution In Vitro of Germ Cell Development in Mammals 147
Kazuki Kurimoto and Mitinori Saitou
Erase-Maintain-Establish: Natural Reprogramming of the Mammalian Epigenome Milena 155
Leseva, Barbara B Knowles, Daniel M Messerschmidt, and Davor Solter
Regulation of Reprogramming and Cellular Plasticity through Histone Exchange and Histone 165
Variant Incorporation Xavier Gaume and Maria-Elena Torres-Padilla
xviii CONTENTS
ZFP5 7 and the Targeted Maintenance of Postfertilization Genomic Imprints Nozomi Takahashi, 177
Dionne Gray, Ruslan Strogantsev, Angela Noon, Celia Delahaye, William C Skarnes,
Peri H Tate, and Anne C Ferguson-Smith
Embryonic Stem Cells and Development
Biological Networks Governing the Acquisition, Maintenance, and Dissolution of Pluripotency: 189
Insights from Functional Genomics Approaches Kevin Andrew Uy Gonzales and
Huck-Hui Ng
Monitoring Dynamics of DNA Methylation at Single-Cell Resolution during Development and 199
Disease Yonatan Stelzer and Rudolf Jaenisch
Perturbing Chromatin Structure to Understand Mechanisms of Gene Expression 207
Caroline R Bartman and Gerd A Blobel
Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers 213
Verena M Link, David Gosselin, and Christopher K Glass
Metabolism and Signaling
Clock-Talk: Interactions between Central and Peripheral Circadian Oscillators in Mammals Ueli 223
Schibler, Ivana Gotic, Camille Saini, Pascal Gos, Thomas Curie, Yann Emmenegger, Flore
Sinturel, Pauline Gosselin, Alan Gerber, Fabienne Fleury-Olela, Gianpaolo Rando, Maud
Demarque, and Paul Franken
Dissecting the Rev-erba Cistrome and the Mechanisms Controlling Circadian Transcription in 233
Liver Bin Fang and Mitchell A Lazar
Modulating the Genomic Programming of Adipocytes Anne Loft, Soren Fisker Schmidt, 239
and Susanne Mandrup
Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and 249
Cancer Nasun Hah, Mara H Sherman, Ruth T Yu, Michael Downes, and Ronald M Evans
Regulation of RORyt in Inflammatory Lymphoid Cell Differentiation Wendy Huang and 257
Dan R Liftman
Evolution
How Transcription Networks Evolve and Produce Biological Novelty Isabel Nocedal and 265
Alexander D Johnson
The African Turquoise Killifish: A Model for Exploring Vertebrate Aging and Diseases in the Fast 275
Lane Itamar Harel and Anne Brunet
Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription 281
Networks Didier Trono
Dorcas Cummings Lecture 289
Svante Pääbo 291
Conversations at the Symposium 295
Genevieve Almouzni 297
Angelika Amon 299
Julius Brennecke 302
Emmanuelle Charpentier , 305
Job Dekker 308
Titia de Lange 311
Jennifer Doudna 314
Denis Duboule 316
Ron Evans 318
Anne Ferguson-Smith 321
Edith Heard 324
David Kingsley 327
CONTENTS
xix
7
9
9
7
3
3
3
9
9
57
65
75
81
89
91
95
97
99
02
05
08
11
14
16
18
21
24
27
■i
Arnold Levine 330
Susan Lindquist 332
Dan Littman 334
Richard Morimoto 336
David Page 338
Wolf Reik 340
Bing Ren 342
Ueli Schibier 344
Davor Solter 346
Alexander Tarakhovsky 348
Joanna Wysocka 351
Rick Young 353
Author Index 355
Contents
Symposium Participants v
Foreword xv
Gene Control
Imaging Transcription: Past, Present, and Future Robert A. Coleman, Zhe Liu, Xavier Darzacq, 1
Robert Tjian, Robert H. Singer, and Timothée Li on net
Visualizing the HoxD Gene Cluster at the Nanoscale Level Pierre J. Fabre, Alexander Benke, 9
Suliana Manley, and Denis Duboule
Transcriptional Enhancers: Bridging the Genome and Phenome Bing Ren and Feng Yue 17
Regulatory Principles Governing Tissue Specificity of Developmental Enhancers Emma K. 27
Farley, Katrina M. Olson, and Michael S. Levine
The Importance of Controlling Transcription Elongation at Coding and Noncoding RNA Loci 33
Benjamin S. Scruggs and Karen Adelman
Chromatin Domains and Nuclear Position
Regulatory Domains and Their Mechanisms Nezha S. Benabdallah and Wendy A. Bickmore 45
Large-Scale Chromatin Structure—Function Relationships during the Cell Cycle and Develop- 53
ment: Insights from Replication Timing Vishnu Dileep, Juan Carlos Rivera-Mulia, Jiao
Sima, and David M. Gilbert
Prenucleosomes and Active Chromatin Mai T Khuong, Jia Fei, Haruhiko Ishii, and 65
James T Kadonaga
HIPMap: A High-Throughput Imaging Method for Mapping Spatial Gene Positions Si gal 73
Shachar; Gianluca Pegoraro, and Tom Misteli
Genome Organization and Chromosome Architecture Giorgio Bernardi 83
Genome Stability
A System to Study Aneuploidy In Vivo Sarah J. Pfau and Angelika Amon 93
Resolution of Recombination Intermediates: Mechanisms and Regulation Stephen C. West, 103
Miguel G. Blanco, Ying Wai Chan, Joao Matos, Shriparna Sarbajna, and Haley D.M. Wyatt
21st Century Genetics: Mass Spectrometry of Yeast Telomerase Kah Wai Lin and 111
Virginia A. Zakian
From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes 117
Cheng-Zhong Zhang and David Pellman
The Evolution of Tumors in Mice and Humans with Germline p53 Mutations Arnold J. Levine, 139
Chang S. Chan, Crissy Dudgeon, Anna Puzio-Kuter, and Pierre Hainaut
Germ Cells and Early Development
Mechanism and Reconstitution In Vitro of Germ Cell Development in Mammals 147
Kazuki Kurimoto and Mitinori Saitou
Erase-Maintain—Establish: Natural Reprogramming of the Mammalian Epigenome Milena 155
Leseva, Barbara B. Knowles, Daniel M. Messerschmidt, and Davor Solter
Regulation of Reprogramming and Cellular Plasticity through Histone Exchange and Histone 165
Variant Incorporation Xavier Gaume and Maria-Elena Torres-Padilla
XVII
xviii
CONTENTS
ZFP57 and the Targeted Maintenance of Postfertilization Genomic Imprints Nozomi Takahashi, 177
Dionne Gray, Ruslan Strogantsev, Angela Noon, Celia Delahaye, William C. Skarnes,
Peri II. Tate, and Anne C. Ferguson-Smith
Embryonic Stem Cells and Development
Biological Networks Governing the Acquisition, Maintenance, and Dissolution of Pluripotency: 189
Insights from Functional Genomics Approaches Kevin Andrew Uy Gonzales and
Huck-Hui Ng
Monitoring Dynamics of DNA Methylation at Single-Cell Resolution during Development and 199
Disease Yonatan Stelzer and Rudolf Jaenisch
Perturbing Chromatin Structure to Understand Mechanisms of Gene Expression 207
Caroline R. Bartman and Gerd A. Blobel
Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers 213
Verena M. Link, David Gosselin, and Christopher K. Glass
Metabolism and Signaling
Clock-Talk: Interactions between Central and Peripheral Circadian Oscillators in Mammals Ueli 223
Schibler, Ivana Gotic, Camille Saini, Pascal Gos, Thomas Curie, Yann Emmenegger, Flore
Sinturel, Pauline Gosselin, Alan Gerber, Fabienne Fleury-Olela, Gianpaolo Rando, Maud
Demarque, and Paul Franken
Dissecting the Rev-erba Cistrome and the Mechanisms Controlling Circadian Transcription in 233
Liver Bin Fang and Mitchell A. Lazar
Modulating the Genomic Programming of Adipocytes Anne Loft, Soren Fisher Schmidt, 239
and Susanne Mandrup
Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and 249
Cancer Nasun Hah, Mara H. Sherman, Ruth T. Yu, Michael Downes, and Ronald M. Evans
Regulation of RORyt in Inflammatory Lymphoid Cell Differentiation Wendy Huang and 257
Dan R. Littman
Evolution
How Transcription Networks Evolve and Produce Biological Novelty Isabel Nocedal and 265
Alexander D. Johnson
The African Turquoise Killifish: A Model for Exploring Vertebrate Aging and Diseases in the Fast 275
Lane Itamar Harel and Anne Brunet
Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription 281
Networks Didier Trono
Dorcas Cummings Lecture 289
Svante Pàabo 291
Conversations at the Symposium 295
Geneviève Almouzni 297
Angelika Amon 299
Julius Brennecke 302
Emmanuelle Charpentier 305
Job Dekker 3Qg
Titia de Lange 311
Jennifer Doudna 314
Denis Duboule 315
Ron Evans 31 g
Anne Ferguson-Smith 321
Edith Heard 324
David Kingsley 327
CONTENTS
xix
Arnold Levine 330
Susan Lindquist 332
Dan Littman 334
Richard Mori moto 336
David Page 338
Wolf Reik 340
Bing Ren 342
Ueli Schibier 344
Davor Solter 346
Alexander Tarakhovsky 348
Joanna Wysocka 351
Rick Young 353
Author Index 355
Subject Index 357
|
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dewey-sort | 3576.5 |
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illustrated | Illustrated |
indexdate | 2024-07-10T07:34:06Z |
institution | BVB |
isbn | 9781621821472 9781621821274 |
language | English |
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spelling | 21st century genetics genes at work symposium organizers and proceedings editors: Terri Grodzicker [und 2 weitere] Twenty-first century genetics Cold Spring Harbor, NY Cold Spring Harbor Laboratory Press 2015 xix, 361 Seiten Illustrationen, Diagramme 28 cm txt rdacontent n rdamedia nc rdacarrier Cold Spring Harbor Symposia on Quantitative Biology 80 Kognition (DE-588)4031630-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2014 Cold Spring Harbor, NY gnd-content Kognition (DE-588)4031630-0 s DE-604 Grodzicker, Terri (DE-588)105305453X edt Cold Spring Harbor Symposia on Quantitative Biology 80 (DE-604)BV010931512 80 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029161742&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029161742&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | 21st century genetics genes at work Cold Spring Harbor Symposia on Quantitative Biology Kognition (DE-588)4031630-0 gnd |
subject_GND | (DE-588)4031630-0 (DE-588)1071861417 |
title | 21st century genetics genes at work |
title_alt | Twenty-first century genetics |
title_auth | 21st century genetics genes at work |
title_exact_search | 21st century genetics genes at work |
title_full | 21st century genetics genes at work symposium organizers and proceedings editors: Terri Grodzicker [und 2 weitere] |
title_fullStr | 21st century genetics genes at work symposium organizers and proceedings editors: Terri Grodzicker [und 2 weitere] |
title_full_unstemmed | 21st century genetics genes at work symposium organizers and proceedings editors: Terri Grodzicker [und 2 weitere] |
title_short | 21st century genetics |
title_sort | 21st century genetics genes at work |
title_sub | genes at work |
topic | Kognition (DE-588)4031630-0 gnd |
topic_facet | Kognition Konferenzschrift 2014 Cold Spring Harbor, NY |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029161742&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029161742&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV010931512 |
work_keys_str_mv | AT grodzickerterri 21stcenturygeneticsgenesatwork AT grodzickerterri twentyfirstcenturygenetics |
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