Polyamines in fungi: their distribution, metabolism, and role in cell differentiation and morphogenesis
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Hauptverfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Boca Raton, Florida
CRC Press
2016
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Schriftenreihe: | Mycology series
Volume 30 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Description based on online resource; title from PDF title page (ebrary, viewed December 8, 2015) |
Beschreibung: | 1 online resource (206 pages) illustrations (some color), tables |
ISBN: | 9781498717427 9781498717434 |
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Datensatz im Suchindex
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adam_text | Titel: Polyamines in fungi
Autor: Valdés-Santiago, Laura
Jahr: 2016
Contents
Preface.......................................................................................................................xi
Acknowledgments..................................................................................................xiii
Authors.....................................................................................................................xv
Chapter 1
Introduction................................................................................................................1
Chapter 2
Chemistry and Cellular Localization of Polyamines.................................................5
2.1 Introduction.....................................................................................................5
2.2 Chemical Structure and Physicochemical Characteristics
of Polyamines and Their Impact on the Interaction with Biomolecules.........7
2.3 Binding of Polyamines with Cellular Macromolecules..................................8
2.4 Physiological Results of the Interactions of Polyamines with Cell
Macromolecules and Structures....................................................................12
2.5 Localization of Polyamines in the Cells of Different Organisms,
Including Fungi.............................................................................................14
Chapter 3
Mechanisms of Polyamines Biosynthesis, Their Interconversion
and Degradation in Fungi, in Comparison with Animal and Plant Cells................21
3.1 Introduction...................................................................................................21
3.2 Pathways of Putrescine Biosynthesis............................................................21
3.3 Mechanisms for the Synthesis of Spermidine...............................................27
3.4 Mechanisms for the Synthesis of Spermine..................................................31
3.5 Mechanisms of Degradation and Interconversion of Polyamines.................33
3.6 Origin and Role of the Different Precursor Molecules Involved
in Polyamine Biosynthesis............................................................................39
3.7 The Relationship of Polyamine Metabolism with Other Cellular
Pathways in Different Organisms.................................................................41
Chapter 4
Polyamine Distribution in the Fungal Kingdom, as Compared with Other
Eukaryotic Organisms.............................................................................................43
4.1 Introduction...................................................................................................43
4.2 Polyamines Present in the Different Fungal Groups and Other Organisms... 44
4.3 Phylogenetic Relationships of the Enzymes Involved in Polyamine
Metabolism in Fungi.....................................................................................46
4.4 Possible Evolution of the Polyamine Biosynthetic Pathways in Fungi.........67
4.5 Advantages of Fungi as Models for the Study of Different Aspects
of Polyamine Metabolism and Their Modes of Action.................................72
vfi
viii
CONTENTS
Chapter 5
Regulatory Mechanisms of Polyamine Metabolism at the Transcriptional,
Translational, and Posttranslational Levels in Fungi and Other Organisms...........79
5.1 Introduction...................................................................................................79
5.2 Regulation of the Synthesis of Ode at the Transcriptional
and Posttranscriptional Levels......................................................................80
5.3 The Unique Mechanism of Az as a Regulatory Protein...............................81
5.4 Regulation of the Biosynthesis of Samdc......................................................85
5.5 Regulation of the Activity of the Polyamine Biosynthetic Enzymes............86
5.6 Regulation of Polyamines during Stress Conditions: A Comparative
Study between Fungal and Plant Cells..........................................................87
Chapter 6
General Functions of Polyamines and Their Possible Modes of Action
in Fungi and Other Organisms................................................................................91
6.1 Introduction...................................................................................................91
6.2 Polyamines Are Essential.............................................................................92
6.3 Role of Polyamines on Cell Growth, Transcription, and Translation
in Fungi and Other Organisms......................................................................93
6.4 Regulation of the Expression of Specific Genes by Polyamines
in Fungi and Other Eukaryotes.....................................................................96
6.5 Regulation by Polyamines of Gene Expression by Modification
of DNA Methylation Patterns.......................................................................97
6.6 Polyamines and the Structure of Cell Membranes.......................................99
6.7 The Role of Polyamines in Stress Response...............................................100
6.8 Selected Aspects of the Role of Polyamines in Some Specific
Cellular Functions.......................................................................................102
6.9 Natural Polyamines and Their Possible Clinical and Biotechnological
Applications................................................................................................103
6.9.1 Polyamines and Their Potential Medical Applications.................104
6.9.1.1 Selected Topics of Polyamines in Cancer......................104
6.9.1.2 Polyamines and Their Potential Application
in Systemic Lupus Erythematosus.................................105
6.9.1.3 Polyamines and Their Potential Application
on Other Affections........................................................106
6.9.2 Polyamine Application as Protective Agent in Plant Development.... 107
6.9.2.1 Polyamines and Resistance to Cold Stress Conditions.... 108
6.9.2.2 Polyamines as Agents for Improvement of Shelf Life... 109
6.9.2.3 Polyamines as Agents against Heavy-Metal-Induced
Stress on Plants...............................................................110
6.9.2.4 Polyamines as Inducing Agents for Plant Development.....111
6.9.2.5 Polyamines as Breeders in Plant Symbiotic
Associations on Economically Important Crops...........Ill
CONTENTS ix
Chapter 7
The Role of Polyamines on Cell Differentiation and Morphogenesis in Fungi
and Other Organisms.............................................................................................113
7.1 Introduction.................................................................................................113
7.2 Differential Locations of Polyamines and Their Relation to Specific
Phenomena..................................................................................................114
7.3 The Use of Fungi as Models for the Study of the Mechanisms
of Polyamine Roles on Cell Differentiation................................................115
7.4 Role of Polyamines on Differentiation in Plants.........................................118
7.5 Use of Fungal and Plant Mutants in the Analysis of the Specific Roles
of the Different Polyamines in Cell Physiology..........................................119
Chapter 8
Polyamine Metabolism as a Target........................................................................121
8.1 Introduction.................................................................................................121
8.2 Effect of Inhibitors on the Different Enzymes Involved in Polyamine
Metabolism..................................................................................................123
8.3 Polyamine Metabolism as a Possible Target for the Control of Some
Human Diseases..........................................................................................127
8.4 Use of the Differences Existing in the Mechanism of Polyamine
Biosynthesis between Plants and Fungi as a Mechanism for the
Control of Phytopathogenic Fungi..............................................................128
8.5 RNA Interference as a Tool to Analyze Polyamine Metabolism and to
Control Pathogens by Selective Inhibition of Polyamine Biosynthesis......130
References..............................................................................................................133
Index......................................................................................................................183
|
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author | Valdés-Santiago, Laura Ruiz-Herrera, José |
author_facet | Valdés-Santiago, Laura Ruiz-Herrera, José |
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discipline | Chemie / Pharmazie |
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spelling | Valdés-Santiago, Laura Verfasser aut Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis Laura Valdés-Santiago, José Ruiz-Herrera Boca Raton, Florida CRC Press 2016 © 2016 1 online resource (206 pages) illustrations (some color), tables txt rdacontent c rdamedia cr rdacarrier Mycology series Volume 30 Description based on online resource; title from PDF title page (ebrary, viewed December 8, 2015) Polyamines Fungi Ruiz-Herrera, José aut Erscheint auch als Druck-Ausgabe Valdés-Santiago, Laura Polyamines in fungi : their distribution, metabolism, and role in cell differentiation and morphogenesis HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029146535&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Valdés-Santiago, Laura Ruiz-Herrera, José Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis Polyamines Fungi |
title | Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis |
title_auth | Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis |
title_exact_search | Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis |
title_full | Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis Laura Valdés-Santiago, José Ruiz-Herrera |
title_fullStr | Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis Laura Valdés-Santiago, José Ruiz-Herrera |
title_full_unstemmed | Polyamines in fungi their distribution, metabolism, and role in cell differentiation and morphogenesis Laura Valdés-Santiago, José Ruiz-Herrera |
title_short | Polyamines in fungi |
title_sort | polyamines in fungi their distribution metabolism and role in cell differentiation and morphogenesis |
title_sub | their distribution, metabolism, and role in cell differentiation and morphogenesis |
topic | Polyamines Fungi |
topic_facet | Polyamines Fungi |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029146535&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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