The search for human chromosomes: a history of discovery
This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the g...
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| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cham ; Heidelberg ; New York ; Dordrecht ; London
Springer
[2016]
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| Schlagworte: | |
| Online-Zugang: | UBG01 UEI01 UPA01 URL des Erstveröffentlichers Inhaltsverzeichnis |
| Zusammenfassung: | This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book |
| Beschreibung: | Introduction -- Background to the Hunt for the Human Chromosome Number -- Microscopes and Stains: The Rise of Technology -- Mendel and Genetics -- Chromosomes as the Carriers of Heredity -- Difficulties of Chromosome Handling and Access to Material -- The Implications of DNA Structure -- Tissue Culture and the Cell Cycle: The Answer is Revealed -- The Flowering of Clinical Genetics -- Sex and Chromosomes -- What we Know, What we Don’t and Where This may Lead us -- Appendix A: Rough Guide to Chromosome Structure -- Appendix B: People in the Text -- Glossary |
| Beschreibung: | 1 Online-Ressource (VII, 179 Seiten) Illustrationen |
| ISBN: | 9783319263366 |
| DOI: | 10.1007/978-3-319-26336-6 |
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| 520 | |a This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book | ||
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Datensatz im Suchindex
| _version_ | 1804176449258651648 |
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| adam_text | Titel: The search for human chromosomes
Autor: Wall, Wilson J
Jahr: 2016
Contents
1 Background to the Hunt for the Human Chromosome
Number............................................................................................1
2 Microscopes and Stains: The Rise of Technology............................17
3 Mendel and Genetics........................................................................33
4 Chromosomes as the Carriers of Heredity......................................49
5 Difficulties of Chromosome Handling and Access to Material.... 61
6 The Implications of DNA Structure................................................73
7 Tissue Culture and the Cell Cycle: The Answer Is Revealed............85
8 The Flowering of Clinical Genetics..................................................103
9 Sex and Chromosomes....................................................................119
10 What We Know, What We Don t and Where This May
Lead Us.....................................................131
Appendix A............................................................................................143
Rough Guide to Chromosome Structure................................................143
Appendix B............................................................................................147
People in the Text..............................................................................147
Glossary..................................................................................................171
Further Reading......................................................................................179
vii
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| spelling | Wall, Wilson John 1953- Verfasser (DE-588)1109067615 aut The search for human chromosomes a history of discovery Wilson John Wall Cham ; Heidelberg ; New York ; Dordrecht ; London Springer [2016] 1 Online-Ressource (VII, 179 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Introduction -- Background to the Hunt for the Human Chromosome Number -- Microscopes and Stains: The Rise of Technology -- Mendel and Genetics -- Chromosomes as the Carriers of Heredity -- Difficulties of Chromosome Handling and Access to Material -- The Implications of DNA Structure -- Tissue Culture and the Cell Cycle: The Answer is Revealed -- The Flowering of Clinical Genetics -- Sex and Chromosomes -- What we Know, What we Don’t and Where This may Lead us -- Appendix A: Rough Guide to Chromosome Structure -- Appendix B: People in the Text -- Glossary This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book Geschichte gnd rswk-swf Geschichte History Human genetics Cell biology Cytologie (DE-588)4070177-3 gnd rswk-swf Humangenetik (DE-588)4072653-8 gnd rswk-swf Humangenetik (DE-588)4072653-8 s Cytologie (DE-588)4070177-3 s Geschichte z DE-604 Erscheint auch als Druckausgabe 978-3-319-26334-2 https://doi.org/10.1007/978-3-319-26336-6 Verlag URL des Erstveröffentlichers Volltext HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029094429&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis text file PDF |
| spellingShingle | Wall, Wilson John 1953- The search for human chromosomes a history of discovery Geschichte History Human genetics Cell biology Cytologie (DE-588)4070177-3 gnd Humangenetik (DE-588)4072653-8 gnd |
| subject_GND | (DE-588)4070177-3 (DE-588)4072653-8 |
| title | The search for human chromosomes a history of discovery |
| title_auth | The search for human chromosomes a history of discovery |
| title_exact_search | The search for human chromosomes a history of discovery |
| title_full | The search for human chromosomes a history of discovery Wilson John Wall |
| title_fullStr | The search for human chromosomes a history of discovery Wilson John Wall |
| title_full_unstemmed | The search for human chromosomes a history of discovery Wilson John Wall |
| title_short | The search for human chromosomes |
| title_sort | the search for human chromosomes a history of discovery |
| title_sub | a history of discovery |
| topic | Geschichte History Human genetics Cell biology Cytologie (DE-588)4070177-3 gnd Humangenetik (DE-588)4072653-8 gnd |
| topic_facet | Geschichte History Human genetics Cell biology Cytologie Humangenetik |
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