Junk DNA: A Journey Through the Dark Matter of the Genome
For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98% of the human genome were dismissed as junk," sequences that serve no purpose. Yet recently researche...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York
Columbia University Press
2015
|
| Schlagworte: | |
| Zusammenfassung: | For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98% of the human genome were dismissed as junk," sequences that serve no purpose. Yet recently researchers have discovered variations and modulations in this junk DNA that underwrite a number of intractable diseases. This knowledge has led to innovative research and treatment approaches that may finally control these conditions.Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word gene" and has engendered a bitter battle over whether or not this genomic nonsense" is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey's book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field |
| Beschreibung: | Description based on publisher supplied metadata and other sources |
| Beschreibung: | 1 online resource (235 pages) |
| ISBN: | 9780231539418 9780231170840 |
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| spelling | Carey, Nessa Verfasser aut Junk DNA A Journey Through the Dark Matter of the Genome New York Columbia University Press 2015 © 2015 1 online resource (235 pages) txt rdacontent c rdamedia cr rdacarrier Description based on publisher supplied metadata and other sources For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98% of the human genome were dismissed as junk," sequences that serve no purpose. Yet recently researchers have discovered variations and modulations in this junk DNA that underwrite a number of intractable diseases. This knowledge has led to innovative research and treatment approaches that may finally control these conditions.Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word gene" and has engendered a bitter battle over whether or not this genomic nonsense" is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey's book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field DNA. Genetic engineering Genomics RNS (DE-588)4076759-0 gnd rswk-swf Exon (DE-588)4201879-1 gnd rswk-swf Proteinsynthese (DE-588)4261878-2 gnd rswk-swf Intron (DE-588)4162195-5 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf Epigenetik (DE-588)7566079-9 gnd rswk-swf Genetischer Fingerabdruck (DE-588)4245149-8 gnd rswk-swf Genetik (DE-588)4071711-2 gnd rswk-swf 1\p (DE-588)4151278-9 Einführung gnd-content Genetik (DE-588)4071711-2 s Proteinsynthese (DE-588)4261878-2 s DNS (DE-588)4070512-2 s RNS (DE-588)4076759-0 s Epigenetik (DE-588)7566079-9 s Intron (DE-588)4162195-5 s Exon (DE-588)4201879-1 s 2\p DE-604 Genetischer Fingerabdruck (DE-588)4245149-8 s 3\p DE-604 Erscheint auch als Druck-Ausgabe Carey, Nessa Junk DNA : A Journey Through the Dark Matter of the Genome 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Carey, Nessa Junk DNA A Journey Through the Dark Matter of the Genome DNA. Genetic engineering Genomics RNS (DE-588)4076759-0 gnd Exon (DE-588)4201879-1 gnd Proteinsynthese (DE-588)4261878-2 gnd Intron (DE-588)4162195-5 gnd DNS (DE-588)4070512-2 gnd Epigenetik (DE-588)7566079-9 gnd Genetischer Fingerabdruck (DE-588)4245149-8 gnd Genetik (DE-588)4071711-2 gnd |
| subject_GND | (DE-588)4076759-0 (DE-588)4201879-1 (DE-588)4261878-2 (DE-588)4162195-5 (DE-588)4070512-2 (DE-588)7566079-9 (DE-588)4245149-8 (DE-588)4071711-2 (DE-588)4151278-9 |
| title | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_auth | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_exact_search | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_full | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_fullStr | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_full_unstemmed | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_short | Junk DNA |
| title_sort | junk dna a journey through the dark matter of the genome |
| title_sub | A Journey Through the Dark Matter of the Genome |
| topic | DNA. Genetic engineering Genomics RNS (DE-588)4076759-0 gnd Exon (DE-588)4201879-1 gnd Proteinsynthese (DE-588)4261878-2 gnd Intron (DE-588)4162195-5 gnd DNS (DE-588)4070512-2 gnd Epigenetik (DE-588)7566079-9 gnd Genetischer Fingerabdruck (DE-588)4245149-8 gnd Genetik (DE-588)4071711-2 gnd |
| topic_facet | DNA. Genetic engineering Genomics RNS Exon Proteinsynthese Intron DNS Epigenetik Genetischer Fingerabdruck Genetik Einführung |
| work_keys_str_mv | AT careynessa junkdnaajourneythroughthedarkmatterofthegenome |