Verfügbarkeit: Sperm Acrosome Biogenesis and Function During Fertilization

Sperm Acrosome Biogenesis and Function During Fertilization:

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Bibliographische Detailangaben
Weitere Verfasser:	Buffone, Mariano G. (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	[Cham] Springer International Publishing 2016
Schriftenreihe:	Advances in Anatomy, Embryology and Cell Biology 220
Schlagworte:	Medicine Human physiology Molecular biology Reproductive medicine Urology Biomedicine Human Physiology Molecular Medicine Reproductive Medicine Medizin Spermium Akrosom
Online-Zugang:	UBR01 Volltext Inhaltsverzeichnis Abstract
Beschreibung:	1 Online-Ressource (VII, 172 p. 19 illus., 16 illus. in color)
ISBN:	9783319305677
DOI:	10.1007/978-3-319-30567-7

Internformat

MARC


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Datensatz im Suchindex

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adam_text	SPERM ACROSOME BIOGENESIS AND FUNCTION DURING FERTILIZATION / : 2016 TABLE OF CONTENTS / INHALTSVERZEICHNIS PREFACE THE ACROSOME REACTION: A HISTORICAL PERSPECTIVE THE ACROSOMAL MATRIX ROLE OF ION CHANNELS IN THE SPERM ACROSOME REACTION THE MOLECULES OF SPERM EXOCYTOSIS SPERM CAPACITATION AND ACROSOME REACTION IN MAMMALIAN SPERM LIPID REGULATION OF ACROSOME EXOCYTOSIS ROLE OF ACTIN CYTOSKELETON DURING MAMMALIAN SPERM ACROSOMAL EXOCYTOSIS SITE OF MAMMALIAN SPERM ACROSOME REACTION DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. SPERM ACROSOME BIOGENESIS AND FUNCTION DURING FERTILIZATION / : 2016 ABSTRACT / INHALTSTEXT OVER THE LAST DECADES, ACROSOMAL EXOCYTOSIS (ALSO CALLED THE “ACROSOME REACTION”) HAS BEEN RECOGNIZED AS PLAYING AN ESSENTIAL ROLE IN FERTILIZATION. SECRETION OF THIS GRANULE IS AN ABSOLUTE REQUIREMENT FOR PHYSIOLOGICAL FERTILIZATION. IN RECENT YEARS, THE STUDY OF MAMMALIAN ACROSOMAL EXOCYTOSIS HAS YIELDED SOME MAJOR ADVANCES THAT CHALLENGE THE LONG-HELD, GENERAL PARADIGMS IN THE FIELD. PRINCIPALLY, THE IDEA THAT SPERM MUST BE ACROSOME-INTACT TO BIND TO THE ZONA PELLUCIDA OF UNFERTILIZED EGGS, BASED LARGELY ON IN VITRO FERTILIZATION STUDIES OF MOUSE OOCYTES DENUDED OF THE CUMULUS OOPHORUS, HAS BEEN OVERTURNED BY EXPERIMENTS USING STATE-OF-THE-ART IMAGING OF CUMULUS-INTACT OOCYTES AND FERTILIZATION EXPERIMENTS WHERE EGGS WERE REINSEMINATED BY ACROSOME-REACTED SPERM RECOVERED FROM THE PERIVITELLINE SPACE OF ZYGOTES. FROM A MOLECULAR POINT OF VIEW, ACROSOME EXOCYTOSIS IS A SYNCHRONIZED AND TIGHTLY REGULATED PROCESS MEDIATED BY MOLECULAR MECHANISMS THAT ARE HOMOLOGOUS TO THOSE REPORTED IN NEUROENDOCRINAL CELL SECRETIONS. THE AUTHORS PROVIDE A BROADER PERSPECTIVE, FOCUSING ON A LIMITED NUMBER OF IMPORTANT TOPICS THAT ARE ESSENTIAL FOR UNDERSTANDING THE MOLECULAR MECHANISMS GOVERNING THIS STEP IN THE FERTILIZATION PROCESS. THEY ALSO DISCUSS MOLECULAR ASPECTS SUCH AS THE SIGNALING PATHWAYS LEADING TO EXOCYTOSIS, INCLUDING THE PARTICIPATION OF ION CHANNELS, LIPIDS, THE FUSION MACHINERY PROTEINS AND THE ACTIN CYTOSKELETON AS WELL AS CELLULAR ASPECTS SUCH AS THE SITE OF ACROSOMAL EXOCYTOSIS AND THE USE OF GENE-MANIPULATED ANIMALS TO STUDY THIS PROCESS. DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
any_adam_object	1
author2	Buffone, Mariano G.
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dewey-sort	3612
dewey-tens	610 - Medicine and health
discipline	Medizin
doi_str_mv	10.1007/978-3-319-30567-7
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series2	Advances in Anatomy, Embryology and Cell Biology
spelling	Sperm Acrosome Biogenesis and Function During Fertilization Mariano G. Buffone, editor [Cham] Springer International Publishing 2016 1 Online-Ressource (VII, 172 p. 19 illus., 16 illus. in color) txt rdacontent c rdamedia cr rdacarrier Advances in Anatomy, Embryology and Cell Biology 220 Medicine Human physiology Molecular biology Reproductive medicine Urology Biomedicine Human Physiology Molecular Medicine Reproductive Medicine Medizin Spermium (DE-588)4135383-3 gnd rswk-swf Akrosom (DE-588)4435833-7 gnd rswk-swf Spermium (DE-588)4135383-3 s Akrosom (DE-588)4435833-7 s DE-604 Buffone, Mariano G. edt Erscheint auch als Druckausgabe 978-3-319-30565-3 Advances in Anatomy, Embryology and Cell Biology 220 (DE-604)BV043279515 220 https://doi.org/10.1007/978-3-319-30567-7 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028994193&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028994193&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract
spellingShingle	Sperm Acrosome Biogenesis and Function During Fertilization Advances in Anatomy, Embryology and Cell Biology Medicine Human physiology Molecular biology Reproductive medicine Urology Biomedicine Human Physiology Molecular Medicine Reproductive Medicine Medizin Spermium (DE-588)4135383-3 gnd Akrosom (DE-588)4435833-7 gnd
subject_GND	(DE-588)4135383-3 (DE-588)4435833-7
title	Sperm Acrosome Biogenesis and Function During Fertilization
title_auth	Sperm Acrosome Biogenesis and Function During Fertilization
title_exact_search	Sperm Acrosome Biogenesis and Function During Fertilization
title_full	Sperm Acrosome Biogenesis and Function During Fertilization Mariano G. Buffone, editor
title_fullStr	Sperm Acrosome Biogenesis and Function During Fertilization Mariano G. Buffone, editor
title_full_unstemmed	Sperm Acrosome Biogenesis and Function During Fertilization Mariano G. Buffone, editor
title_short	Sperm Acrosome Biogenesis and Function During Fertilization
title_sort	sperm acrosome biogenesis and function during fertilization
topic	Medicine Human physiology Molecular biology Reproductive medicine Urology Biomedicine Human Physiology Molecular Medicine Reproductive Medicine Medizin Spermium (DE-588)4135383-3 gnd Akrosom (DE-588)4435833-7 gnd
topic_facet	Medicine Human physiology Molecular biology Reproductive medicine Urology Biomedicine Human Physiology Molecular Medicine Reproductive Medicine Medizin Spermium Akrosom
url	https://doi.org/10.1007/978-3-319-30567-7 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028994193&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028994193&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
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