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Heat Shock Factor:

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Bibliographic Details
Format:	Electronic eBook
Language:	English
Published:	Tokyo Springer Japan 2016
Edition:	1st ed. 2016
Subjects:	Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften
Online Access:	BTU01 HTW01 UBR01 Volltext Inhaltsverzeichnis Abstract
Physical Description:	1 Online-Ressource (VIII, 301 p. 73 illus., 14 illus. in color)
ISBN:	9784431558521
DOI:	10.1007/978-4-431-55852-1

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MARC


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adam_text	HEAT SHOCK FACTOR / : 2016 TABLE OF CONTENTS / INHALTSVERZEICHNIS 1 PROTEOSTASIS AND ADAPTATION TO HIGH TEMPERATURE STRESS 2 STRUCTURE AND FUNCTION OF THE HSF FAMILY MEMBERS 3 REGULATION OF HSF ACTIVATION AND REPRESSION 4 TRANSCRIPTIONAL REGULATION BY HSF 5 HSF1 REGULATION IN AGING AND ITS ROLE IN LONGEVITY 6 HSF MODULATES NEURAL DEVELOPMENT UNDER NORMAL AND STRESS CONDITIONS 7 HSF MAINTAINS SENSORY ORGANS 8 HSF IS REQUIRED FOR GAMETOGENESIS 9 HSF REGULATES IMMUNE AND INFLAMMATORY RESPONSE 10 HEAT SHOCK FACTORS MODULATE CIRCADIAN RHYTHMS 11 HSF INHIBITS THE PROGRESSION OF AGE-RELATED NEURODEGENERATIVE DISEASES 12 HSF AND HEART DISEASES 13 HSF SUPPORTS CANCER 14 HSF1 ACTIVATION BY SMALL CHEMICAL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. HEAT SHOCK FACTOR / : 2016 ABSTRACT / INHALTSTEXT THIS BOOK PRESENTS A LARGE AMOUNT OF INFORMATION RELATED TO THE HEAT SHOCK RESPONSE AND HEAT SHOCK FACTOR (HSF), DESCRIBES CORE OBSERVATIONS ABOUT MOLECULAR MECHANISMS AND PATHOPHYSIOLOGICAL ROLES, AND PROVIDES FUNDAMENTAL CONCEPTS ON THE BASIS OF INFORMATION FROM DIVERSE ASPECTS. THIS ADAPTIVE RESPONSE TO HIGH TEMPERATURE OR PROTEIN MISFOLDING IS A FUNDAMENTAL MECHANISM TO MAINTAIN THE CAPACITY OF PROTEIN HOMEOSTASIS, OR PROTEOSTASIS, AND IS EVOLUTIONALLY CONSERVED AMONG ALL LIVING ORGANISMS, INCLUDING BACTERIA AND HUMANS, ON THE EARTH. FURTHERMORE, PHYSIOLOGICAL AND PATHOLOGICAL ROLES OF HSF HAVE BEEN EXTENSIVELY STUDIED IN FRUIT FLY, WORM, AND MOUSE MODELS. IT HAS BEEN REVEALED THAT HSF PLAYS ROLES IN DEVELOPMENT OF THE BRAIN, REPRODUCTIVE AND SENSORY ORGANS, AND IN AGEING, INFLAMMATION, AND CIRCADIAN RHYTHM. ANALYSIS OF THE MECHANISMS HAVE UNCOVERED THAT HSF EXERTS A WIDE RANGE OF EFFECTS ON GENE EXPRESSION AND EPIGENETIC STATUS ON THE WHOLE GENOME. MOREOVER, LOSS OR GAIN OF HSF FUNCTION IS ALSO CLOSELY RELATED TO PROTEIN-MISFOLDING DISEASES INCLUDING NEURODEGENERATIVE DISEASES, PSYCHIATRIC DISEASES, HEART DISEASES, AND CANCERS. THEREFORE, HSF IS NOW THOUGHT TO BE A PROMISING THERAPEUTIC TARGET FOR TREATMENT OF THESE REFRACTORY DISEASES. FOR UNDERGRADUATE STUDENTS, THIS IS A HIGHLY UNDERSTANDABLE SOURCE OF INFORMATION ON HEART SHOCK RESPONSE AND HSF, COVERING THE BASIS OF HSF BIOLOGY, THE PHYSIOLOGICAL ROLE OF HSF, AND DISEASE ASSOCIATED WITH HSF FUNCTION. THIS BOOK NOT ONLY SERVES AS A GUIDE TO THE HEAT SHOCK RESPONSE AND HSF FOR STUDENTS AND YOUNG RESEARCHERS IN OTHER FIELDS, BUT ALSO IS A CORNERSTONE FOR FUTURE WORK IN THE FIELD RELATED TO THE HEAT SHOCK RESPONSE AND HSF. DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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indexdate	2024-07-10T07:28:32Z
institution	BVB
isbn	9784431558521
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physical	1 Online-Ressource (VIII, 301 p. 73 illus., 14 illus. in color)
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publisher	Springer Japan
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spelling	Heat Shock Factor edited by Akira Nakai 1st ed. 2016 Tokyo Springer Japan 2016 1 Online-Ressource (VIII, 301 p. 73 illus., 14 illus. in color) txt rdacontent c rdamedia cr rdacarrier Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften Nakai, Akira Sonstige oth Erscheint auch als Druckausgabe 978-4-431-55850-7 https://doi.org/10.1007/978-4-431-55852-1 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract
spellingShingle	Heat Shock Factor Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften
title	Heat Shock Factor
title_auth	Heat Shock Factor
title_exact_search	Heat Shock Factor
title_full	Heat Shock Factor edited by Akira Nakai
title_fullStr	Heat Shock Factor edited by Akira Nakai
title_full_unstemmed	Heat Shock Factor edited by Akira Nakai
title_short	Heat Shock Factor
title_sort	heat shock factor
topic	Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften
topic_facet	Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften
url	https://doi.org/10.1007/978-4-431-55852-1 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
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