Heat Shock Factor:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Tokyo
Springer Japan
2016
|
| Ausgabe: | 1st ed. 2016 |
| Schlagworte: | |
| Online-Zugang: | BTU01 HTW01 UBR01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (VIII, 301 p. 73 illus., 14 illus. in color) |
| ISBN: | 9784431558521 |
| DOI: | 10.1007/978-4-431-55852-1 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804176208765648896 |
|---|---|
| adam_text | HEAT SHOCK FACTOR
/
: 2016
TABLE OF CONTENTS / INHALTSVERZEICHNIS
1 PROTEOSTASIS AND ADAPTATION TO HIGH TEMPERATURE STRESS
2 STRUCTURE AND FUNCTION OF THE HSF FAMILY MEMBERS
3 REGULATION OF HSF ACTIVATION AND REPRESSION
4 TRANSCRIPTIONAL REGULATION BY HSF
5 HSF1 REGULATION IN AGING AND ITS ROLE IN LONGEVITY
6 HSF MODULATES NEURAL DEVELOPMENT UNDER NORMAL AND STRESS CONDITIONS
7 HSF MAINTAINS SENSORY ORGANS
8 HSF IS REQUIRED FOR GAMETOGENESIS
9 HSF REGULATES IMMUNE AND INFLAMMATORY RESPONSE
10 HEAT SHOCK FACTORS MODULATE CIRCADIAN RHYTHMS
11 HSF INHIBITS THE PROGRESSION OF AGE-RELATED NEURODEGENERATIVE
DISEASES
12 HSF AND HEART DISEASES
13 HSF SUPPORTS CANCER
14 HSF1 ACTIVATION BY SMALL CHEMICAL COMPOUNDS FOR THE TREATMENT OF
NEURODEGENERATIVE DISEASES
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
HEAT SHOCK FACTOR
/
: 2016
ABSTRACT / INHALTSTEXT
THIS BOOK PRESENTS A LARGE AMOUNT OF INFORMATION RELATED TO THE HEAT
SHOCK RESPONSE AND HEAT SHOCK FACTOR (HSF), DESCRIBES CORE OBSERVATIONS
ABOUT MOLECULAR MECHANISMS AND PATHOPHYSIOLOGICAL ROLES, AND PROVIDES
FUNDAMENTAL CONCEPTS ON THE BASIS OF INFORMATION FROM DIVERSE ASPECTS.
THIS ADAPTIVE RESPONSE TO HIGH TEMPERATURE OR PROTEIN MISFOLDING IS A
FUNDAMENTAL MECHANISM TO MAINTAIN THE CAPACITY OF PROTEIN HOMEOSTASIS,
OR PROTEOSTASIS, AND IS EVOLUTIONALLY CONSERVED AMONG ALL LIVING
ORGANISMS, INCLUDING BACTERIA AND HUMANS, ON THE EARTH. FURTHERMORE,
PHYSIOLOGICAL AND PATHOLOGICAL ROLES OF HSF HAVE BEEN EXTENSIVELY
STUDIED IN FRUIT FLY, WORM, AND MOUSE MODELS. IT HAS BEEN REVEALED THAT
HSF PLAYS ROLES IN DEVELOPMENT OF THE BRAIN, REPRODUCTIVE AND SENSORY
ORGANS, AND IN AGEING, INFLAMMATION, AND CIRCADIAN RHYTHM. ANALYSIS OF
THE MECHANISMS HAVE UNCOVERED THAT HSF EXERTS A WIDE RANGE OF EFFECTS ON
GENE EXPRESSION AND EPIGENETIC STATUS ON THE WHOLE GENOME. MOREOVER,
LOSS OR GAIN OF HSF FUNCTION IS ALSO CLOSELY RELATED TO
PROTEIN-MISFOLDING DISEASES INCLUDING NEURODEGENERATIVE DISEASES,
PSYCHIATRIC DISEASES, HEART DISEASES, AND CANCERS. THEREFORE, HSF IS NOW
THOUGHT TO BE A PROMISING THERAPEUTIC TARGET FOR TREATMENT OF THESE
REFRACTORY DISEASES. FOR UNDERGRADUATE STUDENTS, THIS IS A HIGHLY
UNDERSTANDABLE SOURCE OF INFORMATION ON HEART SHOCK RESPONSE AND HSF,
COVERING THE BASIS OF HSF BIOLOGY, THE PHYSIOLOGICAL ROLE OF HSF, AND
DISEASE ASSOCIATED WITH HSF FUNCTION. THIS BOOK NOT ONLY SERVES AS A
GUIDE TO THE HEAT SHOCK RESPONSE AND HSF FOR STUDENTS AND YOUNG
RESEARCHERS IN OTHER FIELDS, BUT ALSO IS A CORNERSTONE FOR FUTURE WORK
IN THE FIELD RELATED TO THE HEAT SHOCK RESPONSE AND HSF.
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| indexdate | 2024-07-10T07:28:32Z |
| institution | BVB |
| isbn | 9784431558521 |
| language | English |
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| physical | 1 Online-Ressource (VIII, 301 p. 73 illus., 14 illus. in color) |
| psigel | ZDB-2-SBL ZDB-2-SBL_2016_Fremddaten |
| publishDate | 2016 |
| publishDateSearch | 2016 |
| publishDateSort | 2016 |
| publisher | Springer Japan |
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| spelling | Heat Shock Factor edited by Akira Nakai 1st ed. 2016 Tokyo Springer Japan 2016 1 Online-Ressource (VIII, 301 p. 73 illus., 14 illus. in color) txt rdacontent c rdamedia cr rdacarrier Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften Nakai, Akira Sonstige oth Erscheint auch als Druckausgabe 978-4-431-55850-7 https://doi.org/10.1007/978-4-431-55852-1 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Heat Shock Factor Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften |
| title | Heat Shock Factor |
| title_auth | Heat Shock Factor |
| title_exact_search | Heat Shock Factor |
| title_full | Heat Shock Factor edited by Akira Nakai |
| title_fullStr | Heat Shock Factor edited by Akira Nakai |
| title_full_unstemmed | Heat Shock Factor edited by Akira Nakai |
| title_short | Heat Shock Factor |
| title_sort | heat shock factor |
| topic | Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften |
| topic_facet | Life sciences Human physiology Biochemistry Proteins Cell biology Life Sciences Cell Biology Protein Science Human Physiology Animal Biochemistry Biowissenschaften |
| url | https://doi.org/10.1007/978-4-431-55852-1 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962487&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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