Myeloid-Derived Suppressor Cells and Cancer:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cham
Springer International Publishing
2016
|
| Ausgabe: | 1st ed. 2016 |
| Schriftenreihe: | SpringerBriefs in Immunology
|
| Schlagworte: | |
| Online-Zugang: | BTU01 HTW01 UBR01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (IX, 102 p. 8 illus. in color) |
| ISBN: | 9783319268217 |
| ISSN: | 2194-2773 |
| DOI: | 10.1007/978-3-319-26821-7 |
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Datensatz im Suchindex
| _version_ | 1804176208608362496 |
|---|---|
| adam_text | MYELOID-DERIVED SUPPRESSOR CELLS AND CANCER
/ ESCORS, DAVID
: 2016
TABLE OF CONTENTS / INHALTSVERZEICHNIS
CONTROVERSIES IN NEOPLASTIC MYELOPLASIA
DIFFERENTIATION OF MURINE MYELOID-DERIVED SUPPRESSOR CELLS
HUMAN MDSCS
EX VIVO MDSC DIFFERENTIATION MODELS
IMMUNOREGULATORY MYELOID CELLS IN THE TUMOR MICROENVIRONMENT
SIGNAL TRANSDUCER AND ACTIVATION OF TRANSCRIPTION 3: A MASTER REGULATOR
OF MYELOID-DERIVED SUPPRESSOR CELLS
FUTURE PERSPECTIVES
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
MYELOID-DERIVED SUPPRESSOR CELLS AND CANCER
/ ESCORS, DAVID
: 2016
ABSTRACT / INHALTSTEXT
THE BOOK STARTS WITH AN INTRODUCTION TO AND HISTORY OF MYELOID-DERIVED
SUPPRESSOR CELLS (MDSCS), FOLLOWED BY A DESCRIPTION OF THEIR
DIFFERENTIATION, THEIR ROLE IN THE TUMOUR MICROENVIRONMENT AND THEIR
THERAPEUTIC TARGETING. IT CLOSES WITH AN OUTLOOK ON FUTURE DEVELOPMENTS.
IN CANCER PATIENTS, MYELOPOIESIS IS PERTURBED AND INSTEAD OF GENERATING
IMMUNOGENIC MYELOID CELLS (SUCH AS DENDRITIC CELLS, INFLAMMATORY
MACROPHAGES AND GRANULOCYTES), THERE IS AN INCREASE IN HIGHLY IMMATURE
MDSCS. THESE CELLS ARE DISTRIBUTED SYSTEMICALLY, RESULTING IN GENERAL
IMMUNOSUPPRESSION. THEY ALSO INFILTRATE TUMOURS, PROMOTING THEIR
PROGRESSION AND METASTASIS BY INHIBITING THE NATURAL ANTI-TUMOUR IMMUNE
RESPONSE. AS THESE CELLS ALSO INTERACT WITH CLASSICAL ANTI-NEOPLASTIC
TREATMENTS, THEY HAVE BECOME MAJOR THERAPEUTIC TARGETS IN THE
PHARMACEUTICAL INDUSTRY AND IN ONCOLOGY RESEARCH
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
| author | Escors, David |
| author_facet | Escors, David |
| author_role | aut |
| author_sort | Escors, David |
| author_variant | d e de |
| building | Verbundindex |
| bvnumber | BV043547064 |
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| dewey-full | 616.079 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.079 |
| dewey-search | 616.079 |
| dewey-sort | 3616.079 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-3-319-26821-7 |
| edition | 1st ed. 2016 |
| format | Electronic eBook |
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| isbn | 9783319268217 |
| issn | 2194-2773 |
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| spelling | Escors, David Verfasser aut Myeloid-Derived Suppressor Cells and Cancer by David Escors, James E. Talmadge, Karine Breckpot, Jo A. Van Ginderachter, Grazyna Kochan 1st ed. 2016 Cham Springer International Publishing 2016 1 Online-Ressource (IX, 102 p. 8 illus. in color) txt rdacontent c rdamedia cr rdacarrier SpringerBriefs in Immunology 2194-2773 Medicine Cancer research Immunology Oncology Cell biology Biomedicine Cancer Research Cell Biology Medizin Talmadge, James E. Sonstige oth Breckpot, Karine Sonstige oth Van Ginderachter, Jo A. Sonstige oth Kochan, Grazyna Sonstige oth Erscheint auch als Druckausgabe 978-3-319-26819-4 https://doi.org/10.1007/978-3-319-26821-7 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962427&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962427&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Escors, David Myeloid-Derived Suppressor Cells and Cancer Medicine Cancer research Immunology Oncology Cell biology Biomedicine Cancer Research Cell Biology Medizin |
| title | Myeloid-Derived Suppressor Cells and Cancer |
| title_auth | Myeloid-Derived Suppressor Cells and Cancer |
| title_exact_search | Myeloid-Derived Suppressor Cells and Cancer |
| title_full | Myeloid-Derived Suppressor Cells and Cancer by David Escors, James E. Talmadge, Karine Breckpot, Jo A. Van Ginderachter, Grazyna Kochan |
| title_fullStr | Myeloid-Derived Suppressor Cells and Cancer by David Escors, James E. Talmadge, Karine Breckpot, Jo A. Van Ginderachter, Grazyna Kochan |
| title_full_unstemmed | Myeloid-Derived Suppressor Cells and Cancer by David Escors, James E. Talmadge, Karine Breckpot, Jo A. Van Ginderachter, Grazyna Kochan |
| title_short | Myeloid-Derived Suppressor Cells and Cancer |
| title_sort | myeloid derived suppressor cells and cancer |
| topic | Medicine Cancer research Immunology Oncology Cell biology Biomedicine Cancer Research Cell Biology Medizin |
| topic_facet | Medicine Cancer research Immunology Oncology Cell biology Biomedicine Cancer Research Cell Biology Medizin |
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