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Genome Editing: The Next Step in Gene Therapy

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Bibliographic Details
Format:	Electronic eBook
Language:	English
Published:	New York, NY Springer New York 2016
Edition:	1st ed. 2016
Series:	Advances in Experimental Medicine and Biology
Subjects:	Medicine Human genetics Biomedicine Human Genetics Medizin
Online Access:	BTU01 HTW01 UBR01 URL des Erstveröffentlichers Inhaltsverzeichnis Abstract
Physical Description:	1 Online-Ressource (XVI, 263 p. 48 illus., 5 illus. in color)
ISBN:	9781493935093
ISSN:	0065-2598
DOI:	10.1007/978-1-4939-3509-3

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MARC


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Record in the Search Index

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adam_text	GENOME EDITING / : 2016 TABLE OF CONTENTS / INHALTSVERZEICHNIS 1. GENE EDITING: DOUBLE-STRAND BREAK INDUCED GENE TARGETING AND MUTAGENESIS 20 YEARS LATER 2. THE DEVELOPMENT AND USE OF ZINC-FINGER NUCLEASES 3.THE USE AND DEVELOPMENT OF TAL EFFECTOR NUCLEASES 4. GENOME EDITING FOR NEUROMUSCULAR DISEASES 5. PHAGE INTEGRASES FOR GENOME EDITING 6. PRECISE GENOME MODIFICATION USING TRIPLEX FORMING OLIGONUCLEOTIDES AND PEPTIDE NUCLEIC ACIDS 7. GENOME EDITING BY APTAMER-GUIDED GENE TARGETING 8. STIMULATION OF AAV GENE EDITING VIA DSB REPAIR 9. ENGINEERED NUCLEASES AND TRINUCLEOTIDE REPEAT DISEASES 10. USING ENGINEERED NUCLEASES TO CREATE HIV-RESISTANT CELLS 11. STRATEGIES TO DETERMINE OFF-TARGET EFFECTS OF ENGINEERED NUCLEASES DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. GENOME EDITING / : 2016 ABSTRACT / INHALTSTEXT THIS COMPREHENSIVE VOLUME EXPLORES HUMAN GENETIC ENGINEERING ITS PRE-CLINICAL AND CLINICAL APPLICATIONS, CURRENT DEVELOPMENTS, AND AS TREATMENT FOR HEREDITARY DISEASES. IT PRESENTS AND EVALUATES THE MOST RECENT ADVANCES IN THE UNDERSTANDING OF MAMMALIAN HOST DNA REPAIR MECHANISMS, SUCH AS DOUBLE-STRAND BREAK INDUCED GENE TARGETING AND MUTAGENESIS, THE DEVELOPMENT OF ZINC-FINGER NUCLEASES, GENOME EDITING FOR NEUROMUSCULAR DISEASES, PHASE INTEGRASES, TRIPLEX FORMING OLIGONUCLEOTIDES AND PEPTIDE NUCLEIC ACIDS, APTAMER-GUIDED GENE TARGETING, AAV GENE EDITING VIA DSB REPAIR, ENGINEERED NUCLEASES AND TRINUCLEOTIDE REPEAT DISEASES, AND CREATION OF HIV-RESISTANT CELLS. THE EXPERTLY AUTHORED CHAPTERS CONTEXTUALIZE CURRENT DEVELOPMENTS WITHIN THE HISTORY OF GENOME EDITING WHILE ALSO DISCUSSING THE CURRENT AND POTENTIAL SAFETY CONCERNS OF THIS RAPIDLY GROWING FIELD. GENOME EDITING: THE NEXT STEP IN GENE THERAPY, THE LATEST VOLUME IN THE AMERICAN SOCIETY OF GENE AND CELL THERAPY SERIES, DEFTLY ILLUMINATES THE POTENTIAL OF GENETIC ENGINEERING TECHNOLOGY TO ERADICATE TODAY’S DEADLIEST AND MOST PROLIFIC DISEASES. IT IS IDEAL READING FOR CLINICIANS AND RESEARCHERS IN GENETICS AND IMMUNOLOGY. DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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id	DE-604.BV043546964
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indexdate	2024-07-10T07:28:32Z
institution	BVB
isbn	9781493935093
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physical	1 Online-Ressource (XVI, 263 p. 48 illus., 5 illus. in color)
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publisher	Springer New York
record_format	marc
series2	Advances in Experimental Medicine and Biology
spelling	Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus 1st ed. 2016 New York, NY Springer New York 2016 1 Online-Ressource (XVI, 263 p. 48 illus., 5 illus. in color) txt rdacontent c rdamedia cr rdacarrier Advances in Experimental Medicine and Biology 0065-2598 Medicine Human genetics Biomedicine Human Genetics Medizin Cathomen, Toni Sonstige oth Hirsch, Matthew Sonstige oth Porteus, Matthew Sonstige oth Erscheint auch als Druckausgabe 978-1-4939-3507-9 https://doi.org/10.1007/978-1-4939-3509-3 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract
spellingShingle	Genome Editing The Next Step in Gene Therapy Medicine Human genetics Biomedicine Human Genetics Medizin
title	Genome Editing The Next Step in Gene Therapy
title_auth	Genome Editing The Next Step in Gene Therapy
title_exact_search	Genome Editing The Next Step in Gene Therapy
title_full	Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus
title_fullStr	Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus
title_full_unstemmed	Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus
title_short	Genome Editing
title_sort	genome editing the next step in gene therapy
title_sub	The Next Step in Gene Therapy
topic	Medicine Human genetics Biomedicine Human Genetics Medizin
topic_facet	Medicine Human genetics Biomedicine Human Genetics Medizin
url	https://doi.org/10.1007/978-1-4939-3509-3 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
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