Genome Editing: The Next Step in Gene Therapy
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2016
|
| Ausgabe: | 1st ed. 2016 |
| Schriftenreihe: | Advances in Experimental Medicine and Biology
|
| Schlagworte: | |
| Online-Zugang: | BTU01 HTW01 UBR01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (XVI, 263 p. 48 illus., 5 illus. in color) |
| ISBN: | 9781493935093 |
| ISSN: | 0065-2598 |
| DOI: | 10.1007/978-1-4939-3509-3 |
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Datensatz im Suchindex
| _version_ | 1804176208374530048 |
|---|---|
| adam_text | GENOME EDITING
/
: 2016
TABLE OF CONTENTS / INHALTSVERZEICHNIS
1. GENE EDITING: DOUBLE-STRAND BREAK INDUCED GENE TARGETING AND
MUTAGENESIS 20 YEARS LATER
2. THE DEVELOPMENT AND USE OF ZINC-FINGER NUCLEASES
3.THE USE AND DEVELOPMENT OF TAL EFFECTOR NUCLEASES
4. GENOME EDITING FOR NEUROMUSCULAR DISEASES
5. PHAGE INTEGRASES FOR GENOME EDITING
6. PRECISE GENOME MODIFICATION USING TRIPLEX FORMING OLIGONUCLEOTIDES
AND PEPTIDE NUCLEIC ACIDS
7. GENOME EDITING BY APTAMER-GUIDED GENE TARGETING
8. STIMULATION OF AAV GENE EDITING VIA DSB REPAIR
9. ENGINEERED NUCLEASES AND TRINUCLEOTIDE REPEAT DISEASES
10. USING ENGINEERED NUCLEASES TO CREATE HIV-RESISTANT CELLS
11. STRATEGIES TO DETERMINE OFF-TARGET EFFECTS OF ENGINEERED NUCLEASES
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
GENOME EDITING
/
: 2016
ABSTRACT / INHALTSTEXT
THIS COMPREHENSIVE VOLUME EXPLORES HUMAN GENETIC ENGINEERING ITS
PRE-CLINICAL AND CLINICAL APPLICATIONS, CURRENT DEVELOPMENTS, AND AS
TREATMENT FOR HEREDITARY DISEASES. IT PRESENTS AND EVALUATES THE MOST
RECENT ADVANCES IN THE UNDERSTANDING OF MAMMALIAN HOST DNA REPAIR
MECHANISMS, SUCH AS DOUBLE-STRAND BREAK INDUCED GENE TARGETING AND
MUTAGENESIS, THE DEVELOPMENT OF ZINC-FINGER NUCLEASES, GENOME EDITING
FOR NEUROMUSCULAR DISEASES, PHASE INTEGRASES, TRIPLEX FORMING
OLIGONUCLEOTIDES AND PEPTIDE NUCLEIC ACIDS, APTAMER-GUIDED GENE
TARGETING, AAV GENE EDITING VIA DSB REPAIR, ENGINEERED NUCLEASES AND
TRINUCLEOTIDE REPEAT DISEASES, AND CREATION OF HIV-RESISTANT CELLS. THE
EXPERTLY AUTHORED CHAPTERS CONTEXTUALIZE CURRENT DEVELOPMENTS WITHIN THE
HISTORY OF GENOME EDITING WHILE ALSO DISCUSSING THE CURRENT AND
POTENTIAL SAFETY CONCERNS OF THIS RAPIDLY GROWING FIELD. GENOME EDITING:
THE NEXT STEP IN GENE THERAPY, THE LATEST VOLUME IN THE AMERICAN SOCIETY
OF GENE AND CELL THERAPY SERIES, DEFTLY ILLUMINATES THE POTENTIAL OF
GENETIC ENGINEERING TECHNOLOGY TO ERADICATE TODAY’S DEADLIEST AND MOST
PROLIFIC DISEASES. IT IS IDEAL READING FOR CLINICIANS AND RESEARCHERS IN
GENETICS AND IMMUNOLOGY.
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| dewey-hundreds | 600 - Technology (Applied sciences) 500 - Natural sciences and mathematics |
| dewey-ones | 611 - Human anatomy, cytology, histology 599 - Mammalia |
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| discipline | Biologie Medizin |
| doi_str_mv | 10.1007/978-1-4939-3509-3 |
| edition | 1st ed. 2016 |
| format | Electronic eBook |
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| indexdate | 2024-07-10T07:28:32Z |
| institution | BVB |
| isbn | 9781493935093 |
| issn | 0065-2598 |
| language | English |
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| series2 | Advances in Experimental Medicine and Biology |
| spelling | Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus 1st ed. 2016 New York, NY Springer New York 2016 1 Online-Ressource (XVI, 263 p. 48 illus., 5 illus. in color) txt rdacontent c rdamedia cr rdacarrier Advances in Experimental Medicine and Biology 0065-2598 Medicine Human genetics Biomedicine Human Genetics Medizin Cathomen, Toni Sonstige oth Hirsch, Matthew Sonstige oth Porteus, Matthew Sonstige oth Erscheint auch als Druckausgabe 978-1-4939-3507-9 https://doi.org/10.1007/978-1-4939-3509-3 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Genome Editing The Next Step in Gene Therapy Medicine Human genetics Biomedicine Human Genetics Medizin |
| title | Genome Editing The Next Step in Gene Therapy |
| title_auth | Genome Editing The Next Step in Gene Therapy |
| title_exact_search | Genome Editing The Next Step in Gene Therapy |
| title_full | Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus |
| title_fullStr | Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus |
| title_full_unstemmed | Genome Editing The Next Step in Gene Therapy edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus |
| title_short | Genome Editing |
| title_sort | genome editing the next step in gene therapy |
| title_sub | The Next Step in Gene Therapy |
| topic | Medicine Human genetics Biomedicine Human Genetics Medizin |
| topic_facet | Medicine Human genetics Biomedicine Human Genetics Medizin |
| url | https://doi.org/10.1007/978-1-4939-3509-3 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962327&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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