Systems Genetics: Linking Genotypes and Phenotypes
Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciti...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2015
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| Schriftenreihe: | Cambridge Series in Systems Genetics
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| Schlagworte: | |
| Online-Zugang: | BSB01 FHN01 UER01 Volltext |
| Zusammenfassung: | Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies |
| Beschreibung: | Title from publisher's bibliographic system (viewed on 12 Feb 2016) |
| Beschreibung: | 1 online resource (268 pages) |
| ISBN: | 9781139012751 |
| DOI: | 10.1017/CBO9781139012751 |
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| 520 | |a Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies | ||
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Datensatz im Suchindex
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| dewey-full | 576.5 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 576 - Genetics and evolution |
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| dewey-search | 576.5 |
| dewey-sort | 3576.5 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| doi_str_mv | 10.1017/CBO9781139012751 |
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| isbn | 9781139012751 |
| language | English |
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| spelling | Systems Genetics Linking Genotypes and Phenotypes Edited by Florian Markowetz, Michael Boutros Cambridge Cambridge University Press 2015 1 online resource (268 pages) txt rdacontent c rdamedia cr rdacarrier Cambridge Series in Systems Genetics Title from publisher's bibliographic system (viewed on 12 Feb 2016) Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies Phenotype Genetics Functional genomics Phänotyp (DE-588)4248244-6 gnd rswk-swf Genexpression (DE-588)4020136-3 gnd rswk-swf Genexpression (DE-588)4020136-3 s Phänotyp (DE-588)4248244-6 s 1\p DE-604 Markowetz, Florian edt Boutros, Michael (DE-588)1023031132 edt Erscheint auch als Druck-Ausgabe, Hardcover 978-1-107-01384-1 https://doi.org/10.1017/CBO9781139012751 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Systems Genetics Linking Genotypes and Phenotypes Phenotype Genetics Functional genomics Phänotyp (DE-588)4248244-6 gnd Genexpression (DE-588)4020136-3 gnd |
| subject_GND | (DE-588)4248244-6 (DE-588)4020136-3 |
| title | Systems Genetics Linking Genotypes and Phenotypes |
| title_auth | Systems Genetics Linking Genotypes and Phenotypes |
| title_exact_search | Systems Genetics Linking Genotypes and Phenotypes |
| title_full | Systems Genetics Linking Genotypes and Phenotypes Edited by Florian Markowetz, Michael Boutros |
| title_fullStr | Systems Genetics Linking Genotypes and Phenotypes Edited by Florian Markowetz, Michael Boutros |
| title_full_unstemmed | Systems Genetics Linking Genotypes and Phenotypes Edited by Florian Markowetz, Michael Boutros |
| title_short | Systems Genetics |
| title_sort | systems genetics linking genotypes and phenotypes |
| title_sub | Linking Genotypes and Phenotypes |
| topic | Phenotype Genetics Functional genomics Phänotyp (DE-588)4248244-6 gnd Genexpression (DE-588)4020136-3 gnd |
| topic_facet | Phenotype Genetics Functional genomics Phänotyp Genexpression |
| url | https://doi.org/10.1017/CBO9781139012751 |
| work_keys_str_mv | AT markowetzflorian systemsgeneticslinkinggenotypesandphenotypes AT boutrosmichael systemsgeneticslinkinggenotypesandphenotypes |