Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics: homogeneous and heterogeneous approaches
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cham
Springer
[2016]
|
| Ausgabe: | Second edition |
| Schriftenreihe: | Interdisciplinary applied mathematics
30 |
| Schlagworte: | |
| Online-Zugang: | BTU01 FHR01 FRO01 TUM01 UBM01 UBT01 UBW01 UEI01 UPA01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (XXII, 483 Seiten, 157 illus., 1 illus. in color) |
| ISBN: | 9783319275987 |
| DOI: | 10.1007/978-3-319-27598-7 |
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Datensatz im Suchindex
| _version_ | 1804176141178634240 |
|---|---|
| adam_text | MODELING IN BIOPHARMACEUTICS, PHARMACOKINETICS AND PHARMACODYNAMICS
/ MACHERAS, PANOS
: 2016
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PART I: BASIC CONCEPTS
THE GEOMETRY OF NATURE
DIFFUSION AND KINETICS
NONLINEAR DYNAMICS
PART II: MODELING IN BIOPHARMACEUTICS
DRUG RELEASE
DRUG DISSOLUTION
ORAL DRUG ABSORPTION
PART III: MODELING IN PHARMACOKINETICS
EMPIRICAL MODELS
DETERMINISTIC COMPARTMENTAL MODELS
FRACTIONAL PHARMACOKINETICS
MODELING AND SIMULATION IN BIOEQUIVALENCE
STOCHASTIC COMPARTMENTAL MODELS
PART IV: MODELING IN PHARMACODYNAMICS
CLASSICAL PHARMACODYNAMICS
NONCLASSICAL PHARMACODYNAMICS
APPENDICES
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
MODELING IN BIOPHARMACEUTICS, PHARMACOKINETICS AND PHARMACODYNAMICS
/ MACHERAS, PANOS
: 2016
ABSTRACT / INHALTSTEXT
THE STATE OF THE ART IN BIOPHARMACEUTICS, PHARMACOKINETICS, AND
PHARMACODYNAMICS MODELING IS PRESENTED IN THIS NEW SECOND EDITION BOOK.
IT SHOWS HOW ADVANCED PHYSICAL AND MATHEMATICAL METHODS CAN EXPAND
CLASSICAL MODELS IN ORDER TO COVER HETEROGENEOUS DRUG-BIOLOGICAL
PROCESSES AND THERAPEUTIC EFFECTS IN THE BODY. THE BOOK IS DIVIDED INTO
FOUR PARTS; THE FIRST DEALS WITH THE FUNDAMENTAL PRINCIPLES OF FRACTALS,
DIFFUSION AND NONLINEAR DYNAMICS; THE SECOND WITH DRUG DISSOLUTION,
RELEASE, AND ABSORPTION; THE THIRD WITH EPIRICAL, COMPARTMENTAL, AND
STOCHASTIC PHARMACOKINETIC MODELS, WITH TWO NEW CHAPTERS, ONE ON
FRACTIONAL PHARMACOKINETICS AND ONE ON BIOEQUIVALENCE; AND THE FOURTH
MAINLY WITH CLASSICAL AND NONCLASSICAL ASPECTS OF PHARMACODYNAMICS. THE
CLASSICAL MODELS THAT HAVE RELEVANCE AND APPLICATION TO THESE SCIENCES
ARE ALSO CONSIDERED THROUGHOUT.THIS SECOND EDITION HAS NEW INFORMATION
ON REACTION LIMITED MODELS OF DISSOLUTION, NON BINARY BIOPHARMACEUTIC
CLASSIFICATION SYSTEM, TIME VARYING MODELS, AND INTERFACE MODELS. MANY
EXAMPLES ARE USED TO ILLUSTRATE THE INTRINSIC COMPLEXITY OF DRUG
ADMINISTRATION RELATED PHENOMENA IN THE HUMAN, JUSTIFYING THE USE OF
ADVANCED MODELING METHODS. THIS BOOK WILL APPEAL TO GRADUATE STUDENTS
AND RESEARCHERS IN PHARMACOLOGY, PHARMACEUTICAL SCIENCES,
BIOENGINEERING, AND PHYSIOLOGY. REVIEWS OF THE FIRST EDITION: THIS BOOK
PRESENTS A NOVEL MODELLING APPROACH TO BIOPHARMACEUTICS,
PHARMACOKINETICS AND PHARMACODYNAMIC PHENOMENA. THIS STATE-OF-THE-ART
VOLUME WILL BE HELPFUL TO STUDENTS AND RESEARCHERS IN PHARMACOLOGY,
BIOENGINEERING, AND PHYSIOLOGY. THIS BOOK IS A MUST FOR PHARMACEUTICAL
RESEARCHERS TO KEEP UP WITH RECENT DEVELOPMENTS IN THIS FIELD. (P. R.
PARTHASARATHY, ZENTRALBLATT MATH, VOL.1103 (5), 2007) THESE AUTHORS ARE
THE UNIQUE (OR SOLE) CONTRIBUTORS IN THIS AREA THAT ARE WORKING ON THESE
QUESTIONS AND BRING A SPECIAL EXPERTISE TO THE FIELD THAT IS NOW BEING
RECOGNIZED AS ESSENTIAL TO UNDERSTANDING BIOLOGICAL SYSTEM AND
KINETIC/DYNAMIC CHARACTERISTICS IN DRUG DEVELOPMENT...THIS TEXT IS AN
ESSENTIAL PRIMER FOR THOSE WHO WOULD ENVISION THE INCORPORATION OF
HETEROGENEOUS APPROACHES TO SYSTEMS WHERE HOMOGENEOUS APPROACHES ARE NOT
SUFFICIENT TO DESCRIBE THE SYSTEM. (ROBERT R. BIES, JOURNAL OF CLINICAL
PHARMACOLOGY, VOL. 46, 2006)
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
| author | Macheras, Panos Iliadis, Athanassios |
| author_facet | Macheras, Panos Iliadis, Athanassios |
| author_role | aut aut |
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| dewey-ones | 570 - Biology |
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| dewey-tens | 570 - Biology |
| discipline | Biologie Mathematik |
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| edition | Second edition |
| format | Electronic eBook |
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| owner | DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-20 DE-739 DE-634 DE-898 DE-BY-UBR DE-861 DE-703 DE-824 DE-83 |
| owner_facet | DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-20 DE-739 DE-634 DE-898 DE-BY-UBR DE-861 DE-703 DE-824 DE-83 |
| physical | 1 Online-Ressource (XXII, 483 Seiten, 157 illus., 1 illus. in color) |
| psigel | ZDB-2-SMA ZDB-2-SMA_2016 |
| publishDate | 2016 |
| publishDateSearch | 2016 |
| publishDateSort | 2016 |
| publisher | Springer |
| record_format | marc |
| series | Interdisciplinary applied mathematics |
| series2 | Interdisciplinary applied mathematics |
| spelling | Macheras, Panos Verfasser aut Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches Panos Macheras, Athanassios Iliadis Second edition Cham Springer [2016] © 2016 1 Online-Ressource (XXII, 483 Seiten, 157 illus., 1 illus. in color) txt rdacontent c rdamedia cr rdacarrier Interdisciplinary applied mathematics 30 Mathematics Pharmacology Biochemistry Applied mathematics Engineering mathematics Biomathematics Biophysics Biological physics Biomedical engineering Mathematical and Computational Biology Pharmacology/Toxicology Biophysics and Biological Physics Biomedical Engineering Biochemistry, general Applications of Mathematics Mathematik Pharmakokinetik (DE-588)4115557-9 gnd rswk-swf Biopharmazie (DE-588)4006890-0 gnd rswk-swf Biomathematik (DE-588)4139408-2 gnd rswk-swf Pharmakodynamik (DE-588)4174134-1 gnd rswk-swf Biopharmazie (DE-588)4006890-0 s Pharmakokinetik (DE-588)4115557-9 s Pharmakodynamik (DE-588)4174134-1 s Biomathematik (DE-588)4139408-2 s DE-604 Iliadis, Athanassios Verfasser aut Erscheint auch als Druckausgabe 978-3-319-27596-3 Interdisciplinary applied mathematics 30 (DE-604)BV039839973 30 https://doi.org/10.1007/978-3-319-27598-7 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028920306&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028920306&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Macheras, Panos Iliadis, Athanassios Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches Interdisciplinary applied mathematics Mathematics Pharmacology Biochemistry Applied mathematics Engineering mathematics Biomathematics Biophysics Biological physics Biomedical engineering Mathematical and Computational Biology Pharmacology/Toxicology Biophysics and Biological Physics Biomedical Engineering Biochemistry, general Applications of Mathematics Mathematik Pharmakokinetik (DE-588)4115557-9 gnd Biopharmazie (DE-588)4006890-0 gnd Biomathematik (DE-588)4139408-2 gnd Pharmakodynamik (DE-588)4174134-1 gnd |
| subject_GND | (DE-588)4115557-9 (DE-588)4006890-0 (DE-588)4139408-2 (DE-588)4174134-1 |
| title | Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches |
| title_auth | Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches |
| title_exact_search | Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches |
| title_full | Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches Panos Macheras, Athanassios Iliadis |
| title_fullStr | Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches Panos Macheras, Athanassios Iliadis |
| title_full_unstemmed | Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches Panos Macheras, Athanassios Iliadis |
| title_short | Modeling in biopharmaceutics, pharmacokinetics and pharmacodynamics |
| title_sort | modeling in biopharmaceutics pharmacokinetics and pharmacodynamics homogeneous and heterogeneous approaches |
| title_sub | homogeneous and heterogeneous approaches |
| topic | Mathematics Pharmacology Biochemistry Applied mathematics Engineering mathematics Biomathematics Biophysics Biological physics Biomedical engineering Mathematical and Computational Biology Pharmacology/Toxicology Biophysics and Biological Physics Biomedical Engineering Biochemistry, general Applications of Mathematics Mathematik Pharmakokinetik (DE-588)4115557-9 gnd Biopharmazie (DE-588)4006890-0 gnd Biomathematik (DE-588)4139408-2 gnd Pharmakodynamik (DE-588)4174134-1 gnd |
| topic_facet | Mathematics Pharmacology Biochemistry Applied mathematics Engineering mathematics Biomathematics Biophysics Biological physics Biomedical engineering Mathematical and Computational Biology Pharmacology/Toxicology Biophysics and Biological Physics Biomedical Engineering Biochemistry, general Applications of Mathematics Mathematik Pharmakokinetik Biopharmazie Biomathematik Pharmakodynamik |
| url | https://doi.org/10.1007/978-3-319-27598-7 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028920306&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028920306&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV039839973 |
| work_keys_str_mv | AT macheraspanos modelinginbiopharmaceuticspharmacokineticsandpharmacodynamicshomogeneousandheterogeneousapproaches AT iliadisathanassios modelinginbiopharmaceuticspharmacokineticsandpharmacodynamicshomogeneousandheterogeneousapproaches |