Hot-melt extrusion: pharmaceutical applications
Gespeichert in:
Format: | Elektronisch E-Book |
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Sprache: | English |
Veröffentlicht: |
Chichester, West Sussex, UK
Wiley
2012
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Schriftenreihe: | Advances in phamaceutical technology
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Schlagworte: | |
Online-Zugang: | FRO01 UBG01 Volltext Buchcover |
Beschreibung: | "Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets.Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science"-- "First book related to the use of hot melt extrusion for pharmaceutical applications"-- Includes bibliographical references and index |
Beschreibung: | 1 Online-Ressource |
ISBN: | 9781118307878 1118307879 9780470711408 047071140X 9781118307885 1118307887 9780470711415 0470711418 |
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500 | |a Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, | ||
500 | |a bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science"-- | ||
500 | |a "First book related to the use of hot melt extrusion for pharmaceutical applications"-- | ||
500 | |a Includes bibliographical references and index | ||
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650 | 4 | |a Chemie | |
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Datensatz im Suchindex
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any_adam_object | 1 |
building | Verbundindex |
bvnumber | BV043394444 |
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dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
dewey-raw | 615.1/9 |
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indexdate | 2024-07-10T07:24:47Z |
institution | BVB |
isbn | 9781118307878 1118307879 9780470711408 047071140X 9781118307885 1118307887 9780470711415 0470711418 |
language | English |
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series2 | Advances in phamaceutical technology |
spelling | Hot-melt extrusion pharmaceutical applications edited by Dionysios Douroumis Chichester, West Sussex, UK Wiley 2012 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Advances in phamaceutical technology "Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets.Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science"-- "First book related to the use of hot melt extrusion for pharmaceutical applications"-- Includes bibliographical references and index SCIENCE / Chemistry / Organic bisacsh Chemie Molding (Chemical technology) Drugs / Extrusion Pharmaceutical chemistry Drug delivery systems Electronic books Douroumis, Dennis Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 978-0-470-71118-7 Erscheint auch als Druck-Ausgabe, Hardcover 0-470-71118-3 https://onlinelibrary.wiley.com/doi/book/10.1002/9780470711415 Verlag URL des Erstveröffentlichers Volltext SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028813028&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Buchcover |
spellingShingle | Hot-melt extrusion pharmaceutical applications SCIENCE / Chemistry / Organic bisacsh Chemie Molding (Chemical technology) Drugs / Extrusion Pharmaceutical chemistry Drug delivery systems |
title | Hot-melt extrusion pharmaceutical applications |
title_auth | Hot-melt extrusion pharmaceutical applications |
title_exact_search | Hot-melt extrusion pharmaceutical applications |
title_full | Hot-melt extrusion pharmaceutical applications edited by Dionysios Douroumis |
title_fullStr | Hot-melt extrusion pharmaceutical applications edited by Dionysios Douroumis |
title_full_unstemmed | Hot-melt extrusion pharmaceutical applications edited by Dionysios Douroumis |
title_short | Hot-melt extrusion |
title_sort | hot melt extrusion pharmaceutical applications |
title_sub | pharmaceutical applications |
topic | SCIENCE / Chemistry / Organic bisacsh Chemie Molding (Chemical technology) Drugs / Extrusion Pharmaceutical chemistry Drug delivery systems |
topic_facet | SCIENCE / Chemistry / Organic Chemie Molding (Chemical technology) Drugs / Extrusion Pharmaceutical chemistry Drug delivery systems |
url | https://onlinelibrary.wiley.com/doi/book/10.1002/9780470711415 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028813028&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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