Proteomics of biological systems: protein phosphorylation using Mass spectrometry techniques
Gespeichert in:
1. Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Hoboken, N.J.
John Wiley & Sons
©2012
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Schlagworte: | |
Online-Zugang: | FRO01 UBG01 Volltext |
Beschreibung: | Phosphorylation is the addition of a phosphate (PO₄) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies Includes bibliographical references and index |
Beschreibung: | 1 Online-Ressource (xxiii, 350 pages) |
ISBN: | 9781118137048 1118137043 9781118137017 1118137019 9781118028964 1118028961 9781118137031 1118137035 1283282852 9781283282857 |
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500 | |a Includes bibliographical references and index | ||
650 | 4 | |a Electronic resource | |
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Datensatz im Suchindex
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illustrated | Not Illustrated |
indexdate | 2024-07-10T07:24:46Z |
institution | BVB |
isbn | 9781118137048 1118137043 9781118137017 1118137019 9781118028964 1118028961 9781118137031 1118137035 1283282852 9781283282857 |
language | English |
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physical | 1 Online-Ressource (xxiii, 350 pages) |
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spelling | Ham, Bryan M. Verfasser aut Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques Bryan M. Ham Hoboken, N.J. John Wiley & Sons ©2012 1 Online-Ressource (xxiii, 350 pages) txt rdacontent c rdamedia cr rdacarrier Phosphorylation is the addition of a phosphate (PO₄) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies Includes bibliographical references and index Electronic resource SCIENCE / Life Sciences / Biochemistry bisacsh Science fast Naturwissenschaft Proteomics / Methodology Phosphorylation / Research / Methodology Phosphoproteins / Synthesis Mass spectrometry Electronic books https://onlinelibrary.wiley.com/doi/book/10.1002/9781118137048 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Ham, Bryan M. Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques Electronic resource SCIENCE / Life Sciences / Biochemistry bisacsh Science fast Naturwissenschaft Proteomics / Methodology Phosphorylation / Research / Methodology Phosphoproteins / Synthesis Mass spectrometry |
title | Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques |
title_auth | Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques |
title_exact_search | Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques |
title_full | Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques Bryan M. Ham |
title_fullStr | Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques Bryan M. Ham |
title_full_unstemmed | Proteomics of biological systems protein phosphorylation using Mass spectrometry techniques Bryan M. Ham |
title_short | Proteomics of biological systems |
title_sort | proteomics of biological systems protein phosphorylation using mass spectrometry techniques |
title_sub | protein phosphorylation using Mass spectrometry techniques |
topic | Electronic resource SCIENCE / Life Sciences / Biochemistry bisacsh Science fast Naturwissenschaft Proteomics / Methodology Phosphorylation / Research / Methodology Phosphoproteins / Synthesis Mass spectrometry |
topic_facet | Electronic resource SCIENCE / Life Sciences / Biochemistry Science Naturwissenschaft Proteomics / Methodology Phosphorylation / Research / Methodology Phosphoproteins / Synthesis Mass spectrometry |
url | https://onlinelibrary.wiley.com/doi/book/10.1002/9781118137048 |
work_keys_str_mv | AT hambryanm proteomicsofbiologicalsystemsproteinphosphorylationusingmassspectrometrytechniques |