Proteomics of biological systems: protein phosphorylation using Mass spectrometry techniques
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Bibliographische Detailangaben
1. Verfasser: Ham, Bryan M. (VerfasserIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Hoboken, N.J. John Wiley & Sons ©2012
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Beschreibung:Phosphorylation is the addition of a phosphate (PO₄) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies
Includes bibliographical references and index
Beschreibung:1 Online-Ressource (xxiii, 350 pages)
ISBN:9781118137048
1118137043
9781118137017
1118137019
9781118028964
1118028961
9781118137031
1118137035
1283282852
9781283282857

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