Virtual screening: principles, challenges, and practical guidelines
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Weinheim, Germany
Wiley-VCH
©2011
|
| Schriftenreihe: | Methods and principles in medicinal chemistry
v. 48 |
| Schlagworte: | |
| Online-Zugang: | FRO01 UBG01 Volltext |
| Beschreibung: | Includes bibliographical references and index A comprehensive and up-to-date overview, this is both a desktop reference and practical guide for virtual screening applications in drug discovery. Clearly divided into three major sections, the first on principles provides a detailed description of the methods required for and applied in virtual screening, while the second discusses the most important challenges in order to improve the impact and success of virtual screening. Finally, the third, practical part contains several case studies covering the most important scenarios for new drug discovery, accompanied by general guidelines for the entire workflow of virtual screening studies. Throughout, medicinal chemists from academia, as well as from large and small pharmaceutical companies report on their experience and pass on priceless practical advice on how to make best use of these powerful methods. Unique in its focus on the end user, this is a real "how to" book that does not presuppose prior experience in virtual screening or a background in computational chemistry |
| Beschreibung: | 1 Online-Ressource (xxx, 519 pages) |
| ISBN: | 9783527633333 3527633332 3527633324 9783527633326 |
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| spelling | Virtual screening principles, challenges, and practical guidelines edited by Christoph Sotriffer Weinheim, Germany Wiley-VCH ©2011 1 Online-Ressource (xxx, 519 pages) txt rdacontent c rdamedia cr rdacarrier Methods and principles in medicinal chemistry v. 48 Includes bibliographical references and index A comprehensive and up-to-date overview, this is both a desktop reference and practical guide for virtual screening applications in drug discovery. Clearly divided into three major sections, the first on principles provides a detailed description of the methods required for and applied in virtual screening, while the second discusses the most important challenges in order to improve the impact and success of virtual screening. Finally, the third, practical part contains several case studies covering the most important scenarios for new drug discovery, accompanied by general guidelines for the entire workflow of virtual screening studies. Throughout, medicinal chemists from academia, as well as from large and small pharmaceutical companies report on their experience and pass on priceless practical advice on how to make best use of these powerful methods. Unique in its focus on the end user, this is a real "how to" book that does not presuppose prior experience in virtual screening or a background in computational chemistry Drug Discovery High-Throughput Screening Assays / methods Quantitative Structure-Activity Relationship MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Medizin High throughput screening (Drug development) / Computer simulation Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Bioaktive Verbindungen (DE-588)4145589-7 gnd rswk-swf Computersimulation (DE-588)4148259-1 gnd rswk-swf High throughput screening (DE-588)4596131-1 gnd rswk-swf Molekülbibliothek (DE-588)4420227-1 gnd rswk-swf High throughput screening (DE-588)4596131-1 s Bioaktive Verbindungen (DE-588)4145589-7 s Molekülbibliothek (DE-588)4420227-1 s Arzneimittelentwicklung (DE-588)4143176-5 s Computersimulation (DE-588)4148259-1 s 1\p DE-604 Sotriffer, Christoph Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 978-3-527-32636-5 Erscheint auch als Druck-Ausgabe, Hardcover 3-527-32636-7 https://onlinelibrary.wiley.com/doi/book/10.1002/9783527633326 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Virtual screening principles, challenges, and practical guidelines Drug Discovery High-Throughput Screening Assays / methods Quantitative Structure-Activity Relationship MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Medizin High throughput screening (Drug development) / Computer simulation Arzneimittelentwicklung (DE-588)4143176-5 gnd Bioaktive Verbindungen (DE-588)4145589-7 gnd Computersimulation (DE-588)4148259-1 gnd High throughput screening (DE-588)4596131-1 gnd Molekülbibliothek (DE-588)4420227-1 gnd |
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| title | Virtual screening principles, challenges, and practical guidelines |
| title_auth | Virtual screening principles, challenges, and practical guidelines |
| title_exact_search | Virtual screening principles, challenges, and practical guidelines |
| title_full | Virtual screening principles, challenges, and practical guidelines edited by Christoph Sotriffer |
| title_fullStr | Virtual screening principles, challenges, and practical guidelines edited by Christoph Sotriffer |
| title_full_unstemmed | Virtual screening principles, challenges, and practical guidelines edited by Christoph Sotriffer |
| title_short | Virtual screening |
| title_sort | virtual screening principles challenges and practical guidelines |
| title_sub | principles, challenges, and practical guidelines |
| topic | Drug Discovery High-Throughput Screening Assays / methods Quantitative Structure-Activity Relationship MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Medizin High throughput screening (Drug development) / Computer simulation Arzneimittelentwicklung (DE-588)4143176-5 gnd Bioaktive Verbindungen (DE-588)4145589-7 gnd Computersimulation (DE-588)4148259-1 gnd High throughput screening (DE-588)4596131-1 gnd Molekülbibliothek (DE-588)4420227-1 gnd |
| topic_facet | Drug Discovery High-Throughput Screening Assays / methods Quantitative Structure-Activity Relationship MEDICAL / Drug Guides MEDICAL / Nursing / Pharmacology MEDICAL / Pharmacology MEDICAL / Pharmacy Medizin High throughput screening (Drug development) / Computer simulation Arzneimittelentwicklung Bioaktive Verbindungen Computersimulation High throughput screening Molekülbibliothek |
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