Aspartic Acid Proteases as Therapeutic Targets:
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Bibliographic Details
Main Author: Ghosh, Arun K. (Author)
Format: Electronic eBook
Language:English
Published: Weinheim Wiley-VCH 2010
Series:Methods and principles in medicinal chemistry
Subjects:
Online Access:FRO01
UBG01
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Item Description:In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the major therapeutic targets HIV-1 protease, renin, beta-secretase, gamma-secretase, plasmepsins and fungal
Includes bibliographical references and index
Physical Description:1 Online-Ressource (641 pages)
ISBN:9783527630943
3527630945
9783527630950
3527630953

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