Aspartic Acid Proteases as Therapeutic Targets:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Weinheim
Wiley-VCH
2010
|
| Schriftenreihe: | Methods and principles in medicinal chemistry
|
| Schlagworte: | |
| Online-Zugang: | FRO01 UBG01 URL des Erstveröffentlichers |
| Beschreibung: | In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the major therapeutic targets HIV-1 protease, renin, beta-secretase, gamma-secretase, plasmepsins and fungal Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (641 pages) |
| ISBN: | 9783527630943 3527630945 9783527630950 3527630953 |
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Datensatz im Suchindex
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| any_adam_object | |
| author | Ghosh, Arun K. |
| author_facet | Ghosh, Arun K. |
| author_role | aut |
| author_sort | Ghosh, Arun K. |
| author_variant | a k g ak akg |
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| dewey-full | 612.01516 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.01516 |
| dewey-search | 612.01516 |
| dewey-sort | 3612.01516 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Biologie Medizin |
| format | Electronic eBook |
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| isbn | 9783527630943 3527630945 9783527630950 3527630953 |
| language | English |
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| spelling | Ghosh, Arun K. Verfasser aut Aspartic Acid Proteases as Therapeutic Targets Weinheim Wiley-VCH 2010 1 Online-Ressource (641 pages) txt rdacontent c rdamedia cr rdacarrier Methods and principles in medicinal chemistry In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the major therapeutic targets HIV-1 protease, renin, beta-secretase, gamma-secretase, plasmepsins and fungal Includes bibliographical references and index Science: Anatomy / Physiology MEDICAL / Biochemistry bisacsh Medizin Naturwissenschaft Aspartic proteinases Aspartic proteinases / Inhibitors / Therapeutic use Science Aspartatproteasen (DE-588)4290183-2 gnd rswk-swf Targeted drug delivery (DE-588)4302415-4 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Aspartatproteasen (DE-588)4290183-2 s Targeted drug delivery (DE-588)4302415-4 s Arzneimittelentwicklung (DE-588)4143176-5 s 2\p DE-604 Mannhold, Raimund Sonstige oth Kubinyi, Hugo Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 978-3-527-31811-7 Erscheint auch als Druck-Ausgabe, Hardcover 3-527-31811-9 https://onlinelibrary.wiley.com/doi/book/10.1002/9783527630943 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Ghosh, Arun K. Aspartic Acid Proteases as Therapeutic Targets Science: Anatomy / Physiology MEDICAL / Biochemistry bisacsh Medizin Naturwissenschaft Aspartic proteinases Aspartic proteinases / Inhibitors / Therapeutic use Science Aspartatproteasen (DE-588)4290183-2 gnd Targeted drug delivery (DE-588)4302415-4 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| subject_GND | (DE-588)4290183-2 (DE-588)4302415-4 (DE-588)4143176-5 (DE-588)4143413-4 |
| title | Aspartic Acid Proteases as Therapeutic Targets |
| title_auth | Aspartic Acid Proteases as Therapeutic Targets |
| title_exact_search | Aspartic Acid Proteases as Therapeutic Targets |
| title_full | Aspartic Acid Proteases as Therapeutic Targets |
| title_fullStr | Aspartic Acid Proteases as Therapeutic Targets |
| title_full_unstemmed | Aspartic Acid Proteases as Therapeutic Targets |
| title_short | Aspartic Acid Proteases as Therapeutic Targets |
| title_sort | aspartic acid proteases as therapeutic targets |
| topic | Science: Anatomy / Physiology MEDICAL / Biochemistry bisacsh Medizin Naturwissenschaft Aspartic proteinases Aspartic proteinases / Inhibitors / Therapeutic use Science Aspartatproteasen (DE-588)4290183-2 gnd Targeted drug delivery (DE-588)4302415-4 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| topic_facet | Science: Anatomy / Physiology MEDICAL / Biochemistry Medizin Naturwissenschaft Aspartic proteinases Aspartic proteinases / Inhibitors / Therapeutic use Science Aspartatproteasen Targeted drug delivery Arzneimittelentwicklung Aufsatzsammlung |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9783527630943 |
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