Molecular epidemiology of chronic diseases:
Gespeichert in:
Format: | Elektronisch E-Book |
---|---|
Sprache: | English |
Veröffentlicht: |
Chichester, England
J. Wiley
©2008
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Schlagworte: | |
Online-Zugang: | FRO01 UBG01 Volltext |
Beschreibung: | With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research. Covers categories of biomarkers of exposure, susceptibility and disease, includes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studies, emphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologies, demonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracy, discusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposure, explores practical elements of conducting population studies, including biological repositories and ethics. Molecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles Includes bibliographical references and index |
Beschreibung: | 1 Online-Ressource (xiv, 368 pages) |
ISBN: | 9780470725719 0470725710 9780470725726 0470725729 1282342924 9781282342927 |
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500 | |a With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research. | ||
500 | |a Covers categories of biomarkers of exposure, susceptibility and disease, includes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studies, emphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologies, demonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracy, discusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposure, explores practical elements of conducting population studies, including biological repositories and ethics. | ||
500 | |a Molecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles | ||
500 | |a Includes bibliographical references and index | ||
650 | 4 | |a Chronic Disease / epidemiology | |
650 | 4 | |a Biological Markers | |
650 | 4 | |a Epidemiologic Methods | |
650 | 4 | |a Molecular Epidemiology | |
650 | 4 | |a Health | |
650 | 4 | |a Medicine | |
650 | 7 | |a MEDICAL / Health Risk Assessment |2 bisacsh | |
650 | 7 | |a MEDICAL / Epidemiology |2 bisacsh | |
650 | 2 | |a Maladie chronique / épidémiologie | |
650 | 2 | |a Biomarqueurs | |
650 | 2 | |a Méthodes épidémiologiques | |
650 | 2 | |a Épidémiologie moléculaire | |
650 | 7 | |a Chronic diseases / Epidemiology |2 fast | |
650 | 7 | |a Molecular epidemiology |2 fast | |
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650 | 7 | |a Epidemiologie |2 gtt | |
650 | 7 | |a Maladies chroniques / Épidémiologie |2 ram | |
650 | 7 | |a Molekulare Diagnostik |2 swd | |
650 | 7 | |a Biomarker |2 swd | |
650 | 7 | |a Epidemiologie |2 swd | |
650 | 4 | |a Medizin | |
650 | 4 | |a Molecular epidemiology | |
650 | 4 | |a Chronic diseases / Epidemiology | |
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700 | 1 | |a Vineis, Paolo |e Sonstige |4 oth | |
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Datensatz im Suchindex
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dewey-full | 614.4 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 614 - Forensic medicine; incidence of disease |
dewey-raw | 614.4 |
dewey-search | 614.4 |
dewey-sort | 3614.4 |
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illustrated | Not Illustrated |
indexdate | 2024-07-10T07:24:42Z |
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isbn | 9780470725719 0470725710 9780470725726 0470725729 1282342924 9781282342927 |
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spelling | Molecular epidemiology of chronic diseases editors, Chris Wild, Paolo Vineis, Seymour Garte Chichester, England J. Wiley ©2008 1 Online-Ressource (xiv, 368 pages) txt rdacontent c rdamedia cr rdacarrier With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research. Covers categories of biomarkers of exposure, susceptibility and disease, includes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studies, emphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologies, demonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracy, discusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposure, explores practical elements of conducting population studies, including biological repositories and ethics. Molecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles Includes bibliographical references and index Chronic Disease / epidemiology Biological Markers Epidemiologic Methods Molecular Epidemiology Health Medicine MEDICAL / Health Risk Assessment bisacsh MEDICAL / Epidemiology bisacsh Maladie chronique / épidémiologie Biomarqueurs Méthodes épidémiologiques Épidémiologie moléculaire Chronic diseases / Epidemiology fast Molecular epidemiology fast Chronische ziekten gtt Moleculaire biologie gtt Merkstoffen (geneeskunde) gtt Epidemiologie gtt Maladies chroniques / Épidémiologie ram Molekulare Diagnostik swd Biomarker swd Epidemiologie swd Medizin Molecular epidemiology Chronic diseases / Epidemiology Wild, Chris Sonstige oth Vineis, Paolo Sonstige oth Garte, Seymour J. Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 0-470-02743-6 Erscheint auch als Druck-Ausgabe, Hardcover 978-0-470-02743-1 https://onlinelibrary.wiley.com/doi/book/10.1002/9780470725726 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Molecular epidemiology of chronic diseases Chronic Disease / epidemiology Biological Markers Epidemiologic Methods Molecular Epidemiology Health Medicine MEDICAL / Health Risk Assessment bisacsh MEDICAL / Epidemiology bisacsh Maladie chronique / épidémiologie Biomarqueurs Méthodes épidémiologiques Épidémiologie moléculaire Chronic diseases / Epidemiology fast Molecular epidemiology fast Chronische ziekten gtt Moleculaire biologie gtt Merkstoffen (geneeskunde) gtt Epidemiologie gtt Maladies chroniques / Épidémiologie ram Molekulare Diagnostik swd Biomarker swd Epidemiologie swd Medizin Molecular epidemiology Chronic diseases / Epidemiology |
title | Molecular epidemiology of chronic diseases |
title_auth | Molecular epidemiology of chronic diseases |
title_exact_search | Molecular epidemiology of chronic diseases |
title_full | Molecular epidemiology of chronic diseases editors, Chris Wild, Paolo Vineis, Seymour Garte |
title_fullStr | Molecular epidemiology of chronic diseases editors, Chris Wild, Paolo Vineis, Seymour Garte |
title_full_unstemmed | Molecular epidemiology of chronic diseases editors, Chris Wild, Paolo Vineis, Seymour Garte |
title_short | Molecular epidemiology of chronic diseases |
title_sort | molecular epidemiology of chronic diseases |
topic | Chronic Disease / epidemiology Biological Markers Epidemiologic Methods Molecular Epidemiology Health Medicine MEDICAL / Health Risk Assessment bisacsh MEDICAL / Epidemiology bisacsh Maladie chronique / épidémiologie Biomarqueurs Méthodes épidémiologiques Épidémiologie moléculaire Chronic diseases / Epidemiology fast Molecular epidemiology fast Chronische ziekten gtt Moleculaire biologie gtt Merkstoffen (geneeskunde) gtt Epidemiologie gtt Maladies chroniques / Épidémiologie ram Molekulare Diagnostik swd Biomarker swd Epidemiologie swd Medizin Molecular epidemiology Chronic diseases / Epidemiology |
topic_facet | Chronic Disease / epidemiology Biological Markers Epidemiologic Methods Molecular Epidemiology Health Medicine MEDICAL / Health Risk Assessment MEDICAL / Epidemiology Maladie chronique / épidémiologie Biomarqueurs Méthodes épidémiologiques Épidémiologie moléculaire Chronic diseases / Epidemiology Molecular epidemiology Chronische ziekten Moleculaire biologie Merkstoffen (geneeskunde) Epidemiologie Maladies chroniques / Épidémiologie Molekulare Diagnostik Biomarker Medizin |
url | https://onlinelibrary.wiley.com/doi/book/10.1002/9780470725726 |
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