Linker strategies in solid-phase organic synthesis:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Chichester, U.K.
Wiley
©2009
|
| Schlagworte: | |
| Online-Zugang: | DE-861 DE-473 URL des Erstveröffentlichers |
| Beschreibung: | Includes bibliographical references and index Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been developed and are now routinely employed in solid-phase synthesis. Linker Strategies in Solid-Phase Organic Synthesis guides the reader through the evolution of linker units from their genesis in solid-supported peptide chemistry to the cutting edge diversity linker units that are defining a new era of solid phase synthesis. Individual linker classes are covered in easy to follow chapters written by international experts in their respective fields and offer a comprehensive guide to linker technology whilst simultaneously serving as a handbook of synthetic transformations now possible on solid supports. Topics include: the principles of solid phase organic synthesis, electrophile and nucleophile cleavable linker units, cyclative cleavage as a solid phase strategy, photocleavable linker units, safety-catch linker units, enzyme cleavable linker units, T1 and T2 -versatile triazene linker groups, hydrazone linker units, benzotriazole linker units, phosphorus linker units, sulfur linker units, selenium and tellurium linker units, sulfur, oxygen and selenium linker units cleaved by radical processes, silicon and germanium linker units, boron and stannane linker units, bismuth linker units, transition metal carbonyl linker units, linkers releasing olefins or cycloolefins by ring-closing metathesis, fluorous linker units, solid-phase radiochemistry. The book concludes with extensive linker selection tables, cataloguing the linker units described in this book according to the substrate liberated upon cleavage and conditions used to achieve such cleavage, enabling readers to choose the right linker unit for their synthesis. Linker Strategies in Solid-Phase Organic Synthesis is an essential guide to the diversity of linker units for organic chemists in academia and industry working in the broad areas of solid-phase organic synthesis and diversity oriented synthesis, medicinal chemists in the pharmaceutical industry who routinely employ solid-phase chemistry in the drug discovery business, and advanced undergraduates, postgraduates, and organic chemists with an interest in leading-edge developments in their field |
| Beschreibung: | 1 Online-Ressource (xxviii, 677 pages) |
| ISBN: | 9780470749050 0470749059 9780470511169 0470511168 9780470749043 0470749040 |
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| 500 | |a Includes bibliographical references and index | ||
| 500 | |a Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been developed and are now routinely employed in solid-phase synthesis. Linker Strategies in Solid-Phase Organic Synthesis guides the reader through the evolution of linker units from their genesis in solid-supported peptide chemistry to the cutting edge diversity linker units that are defining a new era of solid phase synthesis. Individual linker classes are covered in easy to follow chapters written by international experts in their respective fields and offer a comprehensive guide to linker technology whilst simultaneously serving as a handbook of synthetic transformations now possible on solid supports. | ||
| 500 | |a Topics include: the principles of solid phase organic synthesis, electrophile and nucleophile cleavable linker units, cyclative cleavage as a solid phase strategy, photocleavable linker units, safety-catch linker units, enzyme cleavable linker units, T1 and T2 -versatile triazene linker groups, hydrazone linker units, benzotriazole linker units, phosphorus linker units, sulfur linker units, selenium and tellurium linker units, sulfur, oxygen and selenium linker units cleaved by radical processes, silicon and germanium linker units, boron and stannane linker units, bismuth linker units, transition metal carbonyl linker units, linkers releasing olefins or cycloolefins by ring-closing metathesis, fluorous linker units, solid-phase radiochemistry. | ||
| 500 | |a The book concludes with extensive linker selection tables, cataloguing the linker units described in this book according to the substrate liberated upon cleavage and conditions used to achieve such cleavage, enabling readers to choose the right linker unit for their synthesis. Linker Strategies in Solid-Phase Organic Synthesis is an essential guide to the diversity of linker units for organic chemists in academia and industry working in the broad areas of solid-phase organic synthesis and diversity oriented synthesis, medicinal chemists in the pharmaceutical industry who routinely employ solid-phase chemistry in the drug discovery business, and advanced undergraduates, postgraduates, and organic chemists with an interest in leading-edge developments in their field | ||
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Datensatz im Suchindex
| _version_ | 1823773598547968000 |
|---|---|
| adam_text | |
| any_adam_object | |
| author | Scott, Peter J. H. |
| author_facet | Scott, Peter J. H. |
| author_role | aut |
| author_sort | Scott, Peter J. H. |
| author_variant | p j h s pjh pjhs |
| building | Verbundindex |
| bvnumber | BV043390549 |
| collection | ZDB-35-WIC |
| ctrlnum | (ZDB-35-WIC)ocn501316340 (OCoLC)501316340 (DE-599)BVBBV043390549 |
| dewey-full | 547/.2 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 547 - Organic chemistry |
| dewey-raw | 547/.2 |
| dewey-search | 547/.2 |
| dewey-sort | 3547 12 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie |
| format | Electronic eBook |
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| id | DE-604.BV043390549 |
| illustrated | Not Illustrated |
| indexdate | 2025-02-11T15:00:39Z |
| institution | BVB |
| isbn | 9780470749050 0470749059 9780470511169 0470511168 9780470749043 0470749040 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028809133 |
| oclc_num | 501316340 |
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| owner_facet | DE-861 |
| physical | 1 Online-Ressource (xxviii, 677 pages) |
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| publishDate | 2009 |
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| publishDateSort | 2009 |
| publisher | Wiley |
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| spelling | Scott, Peter J. H. Verfasser aut Linker strategies in solid-phase organic synthesis edited by Peter J.H. Scott Chichester, U.K. Wiley ©2009 1 Online-Ressource (xxviii, 677 pages) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been developed and are now routinely employed in solid-phase synthesis. Linker Strategies in Solid-Phase Organic Synthesis guides the reader through the evolution of linker units from their genesis in solid-supported peptide chemistry to the cutting edge diversity linker units that are defining a new era of solid phase synthesis. Individual linker classes are covered in easy to follow chapters written by international experts in their respective fields and offer a comprehensive guide to linker technology whilst simultaneously serving as a handbook of synthetic transformations now possible on solid supports. Topics include: the principles of solid phase organic synthesis, electrophile and nucleophile cleavable linker units, cyclative cleavage as a solid phase strategy, photocleavable linker units, safety-catch linker units, enzyme cleavable linker units, T1 and T2 -versatile triazene linker groups, hydrazone linker units, benzotriazole linker units, phosphorus linker units, sulfur linker units, selenium and tellurium linker units, sulfur, oxygen and selenium linker units cleaved by radical processes, silicon and germanium linker units, boron and stannane linker units, bismuth linker units, transition metal carbonyl linker units, linkers releasing olefins or cycloolefins by ring-closing metathesis, fluorous linker units, solid-phase radiochemistry. The book concludes with extensive linker selection tables, cataloguing the linker units described in this book according to the substrate liberated upon cleavage and conditions used to achieve such cleavage, enabling readers to choose the right linker unit for their synthesis. Linker Strategies in Solid-Phase Organic Synthesis is an essential guide to the diversity of linker units for organic chemists in academia and industry working in the broad areas of solid-phase organic synthesis and diversity oriented synthesis, medicinal chemists in the pharmaceutical industry who routinely employ solid-phase chemistry in the drug discovery business, and advanced undergraduates, postgraduates, and organic chemists with an interest in leading-edge developments in their field Science Science: Chemistry SCIENCE / Chemistry / Organic bisacsh Solid-phase synthesis fast Chemie Naturwissenschaft Solid-phase synthesis Organische Synthese (DE-588)4075695-6 gnd rswk-swf Festphasentechnik (DE-588)4154192-3 gnd rswk-swf Linker (DE-588)4510937-0 gnd rswk-swf Organische Synthese (DE-588)4075695-6 s Festphasentechnik (DE-588)4154192-3 s Linker (DE-588)4510937-0 s 1\p DE-604 https://onlinelibrary.wiley.com/doi/book/10.1002/9780470749043 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Scott, Peter J. H. Linker strategies in solid-phase organic synthesis Science Science: Chemistry SCIENCE / Chemistry / Organic bisacsh Solid-phase synthesis fast Chemie Naturwissenschaft Solid-phase synthesis Organische Synthese (DE-588)4075695-6 gnd Festphasentechnik (DE-588)4154192-3 gnd Linker (DE-588)4510937-0 gnd |
| subject_GND | (DE-588)4075695-6 (DE-588)4154192-3 (DE-588)4510937-0 |
| title | Linker strategies in solid-phase organic synthesis |
| title_auth | Linker strategies in solid-phase organic synthesis |
| title_exact_search | Linker strategies in solid-phase organic synthesis |
| title_full | Linker strategies in solid-phase organic synthesis edited by Peter J.H. Scott |
| title_fullStr | Linker strategies in solid-phase organic synthesis edited by Peter J.H. Scott |
| title_full_unstemmed | Linker strategies in solid-phase organic synthesis edited by Peter J.H. Scott |
| title_short | Linker strategies in solid-phase organic synthesis |
| title_sort | linker strategies in solid phase organic synthesis |
| topic | Science Science: Chemistry SCIENCE / Chemistry / Organic bisacsh Solid-phase synthesis fast Chemie Naturwissenschaft Solid-phase synthesis Organische Synthese (DE-588)4075695-6 gnd Festphasentechnik (DE-588)4154192-3 gnd Linker (DE-588)4510937-0 gnd |
| topic_facet | Science Science: Chemistry SCIENCE / Chemistry / Organic Solid-phase synthesis Chemie Naturwissenschaft Organische Synthese Festphasentechnik Linker |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9780470749043 |
| work_keys_str_mv | AT scottpeterjh linkerstrategiesinsolidphaseorganicsynthesis |