Molecular drug properties: measurement and prediction
Gespeichert in:
Format: | Elektronisch E-Book |
---|---|
Sprache: | English |
Veröffentlicht: |
Weinheim
Wiley-VCH
©2008
|
Schriftenreihe: | Methods and principles in medicinal chemistry
v. 37 |
Schlagworte: | |
Online-Zugang: | FRO01 UBG01 Volltext |
Beschreibung: | Includes bibliographical references and index This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity, solubility, electronic properties and conformation |
Beschreibung: | 1 Online-Ressource (xxx, 471 pages) |
ISBN: | 3527621296 9783527621293 128201059X 9781282010598 9783527621286 3527621288 |
Internformat
MARC
LEADER | 00000nmm a2200000zcb4500 | ||
---|---|---|---|
001 | BV043387868 | ||
003 | DE-604 | ||
005 | 00000000000000.0 | ||
007 | cr|uuu---uuuuu | ||
008 | 160222s2008 |||| o||u| ||||||eng d | ||
020 | |a 3527621296 |c electronic bk. |9 3-527-62129-6 | ||
020 | |a 9783527621293 |c electronic bk. |9 978-3-527-62129-3 | ||
020 | |a 128201059X |9 1-282-01059-X | ||
020 | |a 9781282010598 |9 978-1-282-01059-8 | ||
020 | |a 9783527621286 |9 978-3-527-62128-6 | ||
020 | |a 3527621288 |9 3-527-62128-8 | ||
024 | 7 | |a 10.1002/9783527621286 |2 doi | |
035 | |a (ZDB-35-WIC)ocn214281843 | ||
035 | |a (OCoLC)214281843 | ||
035 | |a (DE-599)BVBBV043387868 | ||
040 | |a DE-604 |b ger |e aacr | ||
041 | 0 | |a eng | |
049 | |a DE-861 | ||
082 | 0 | |a 615.7 |2 22 | |
084 | |a VX 5200 |0 (DE-625)147798:253 |2 rvk | ||
245 | 1 | 0 | |a Molecular drug properties |b measurement and prediction |c edited by Raimund Mannhold |
264 | 1 | |a Weinheim |b Wiley-VCH |c ©2008 | |
300 | |a 1 Online-Ressource (xxx, 471 pages) | ||
336 | |b txt |2 rdacontent | ||
337 | |b c |2 rdamedia | ||
338 | |b cr |2 rdacarrier | ||
490 | 0 | |a Methods and principles in medicinal chemistry |v v. 37 | |
500 | |a Includes bibliographical references and index | ||
500 | |a This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity, solubility, electronic properties and conformation | ||
650 | 4 | |a Pharmaceutical Preparations / metabolism | |
650 | 4 | |a Chemistry, Pharmaceutical / methods | |
650 | 4 | |a Models, Molecular | |
650 | 4 | |a Pharmacokinetics | |
650 | 4 | |a Pharmacy | |
650 | 4 | |a Medicine | |
650 | 7 | |a MEDICAL / Pharmacology |2 bisacsh | |
650 | 7 | |a Drug development |2 fast | |
650 | 7 | |a Drugs / Structure-activity relationships |2 fast | |
650 | 4 | |a Medizin | |
650 | 4 | |a Drugs / Structure-activity relationships | |
650 | 4 | |a Drug development | |
650 | 0 | 7 | |a Pharmakokinetik |0 (DE-588)4115557-9 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Arzneimittelentwicklung |0 (DE-588)4143176-5 |2 gnd |9 rswk-swf |
655 | 7 | |8 1\p |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
689 | 0 | 0 | |a Arzneimittelentwicklung |0 (DE-588)4143176-5 |D s |
689 | 0 | 1 | |a Pharmakokinetik |0 (DE-588)4115557-9 |D s |
689 | 0 | |8 2\p |5 DE-604 | |
700 | 1 | |a Mannhold, Raimund |e Sonstige |4 oth | |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe, Hardcover |z 3-527-31755-4 |
856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
912 | |a ZDB-35-WIC | ||
940 | 1 | |q UBG_PDA_WIC | |
999 | |a oai:aleph.bib-bvb.de:BVB01-028806452 | ||
883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
883 | 1 | |8 2\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
966 | e | |u https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286 |l FRO01 |p ZDB-35-WIC |q FRO_PDA_WIC |x Verlag |3 Volltext | |
966 | e | |u https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286 |l UBG01 |p ZDB-35-WIC |q UBG_PDA_WIC |x Verlag |3 Volltext |
Datensatz im Suchindex
_version_ | 1804175958742138880 |
---|---|
any_adam_object | |
building | Verbundindex |
bvnumber | BV043387868 |
classification_rvk | VX 5200 |
collection | ZDB-35-WIC |
ctrlnum | (ZDB-35-WIC)ocn214281843 (OCoLC)214281843 (DE-599)BVBBV043387868 |
dewey-full | 615.7 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
dewey-raw | 615.7 |
dewey-search | 615.7 |
dewey-sort | 3615.7 |
dewey-tens | 610 - Medicine and health |
discipline | Chemie / Pharmazie Medizin |
format | Electronic eBook |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03439nmm a2200709zcb4500</leader><controlfield tag="001">BV043387868</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">160222s2008 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3527621296</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">3-527-62129-6</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783527621293</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">978-3-527-62129-3</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">128201059X</subfield><subfield code="9">1-282-01059-X</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781282010598</subfield><subfield code="9">978-1-282-01059-8</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783527621286</subfield><subfield code="9">978-3-527-62128-6</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3527621288</subfield><subfield code="9">3-527-62128-8</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1002/9783527621286</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-35-WIC)ocn214281843</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)214281843</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043387868</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-861</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615.7</subfield><subfield code="2">22</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VX 5200</subfield><subfield code="0">(DE-625)147798:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Molecular drug properties</subfield><subfield code="b">measurement and prediction</subfield><subfield code="c">edited by Raimund Mannhold</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Weinheim</subfield><subfield code="b">Wiley-VCH</subfield><subfield code="c">©2008</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (xxx, 471 pages)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods and principles in medicinal chemistry</subfield><subfield code="v">v. 37</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity, solubility, electronic properties and conformation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmaceutical Preparations / metabolism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chemistry, Pharmaceutical / methods</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Models, Molecular</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacokinetics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Pharmacology</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Drug development</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Drugs / Structure-activity relationships</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medizin</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drugs / Structure-activity relationships</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drug development</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmakokinetik</subfield><subfield code="0">(DE-588)4115557-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Arzneimittelentwicklung</subfield><subfield code="0">(DE-588)4143176-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="8">1\p</subfield><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Arzneimittelentwicklung</subfield><subfield code="0">(DE-588)4143176-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Pharmakokinetik</subfield><subfield code="0">(DE-588)4115557-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">2\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mannhold, Raimund</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe, Hardcover</subfield><subfield code="z">3-527-31755-4</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-35-WIC</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">UBG_PDA_WIC</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-028806452</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">2\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286</subfield><subfield code="l">FRO01</subfield><subfield code="p">ZDB-35-WIC</subfield><subfield code="q">FRO_PDA_WIC</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286</subfield><subfield code="l">UBG01</subfield><subfield code="p">ZDB-35-WIC</subfield><subfield code="q">UBG_PDA_WIC</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
genre | 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content |
genre_facet | Aufsatzsammlung |
id | DE-604.BV043387868 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T07:24:34Z |
institution | BVB |
isbn | 3527621296 9783527621293 128201059X 9781282010598 9783527621286 3527621288 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028806452 |
oclc_num | 214281843 |
open_access_boolean | |
owner | DE-861 |
owner_facet | DE-861 |
physical | 1 Online-Ressource (xxx, 471 pages) |
psigel | ZDB-35-WIC UBG_PDA_WIC ZDB-35-WIC FRO_PDA_WIC ZDB-35-WIC UBG_PDA_WIC |
publishDate | 2008 |
publishDateSearch | 2008 |
publishDateSort | 2008 |
publisher | Wiley-VCH |
record_format | marc |
series2 | Methods and principles in medicinal chemistry |
spelling | Molecular drug properties measurement and prediction edited by Raimund Mannhold Weinheim Wiley-VCH ©2008 1 Online-Ressource (xxx, 471 pages) txt rdacontent c rdamedia cr rdacarrier Methods and principles in medicinal chemistry v. 37 Includes bibliographical references and index This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity, solubility, electronic properties and conformation Pharmaceutical Preparations / metabolism Chemistry, Pharmaceutical / methods Models, Molecular Pharmacokinetics Pharmacy Medicine MEDICAL / Pharmacology bisacsh Drug development fast Drugs / Structure-activity relationships fast Medizin Drugs / Structure-activity relationships Drug development Pharmakokinetik (DE-588)4115557-9 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Arzneimittelentwicklung (DE-588)4143176-5 s Pharmakokinetik (DE-588)4115557-9 s 2\p DE-604 Mannhold, Raimund Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 3-527-31755-4 https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Molecular drug properties measurement and prediction Pharmaceutical Preparations / metabolism Chemistry, Pharmaceutical / methods Models, Molecular Pharmacokinetics Pharmacy Medicine MEDICAL / Pharmacology bisacsh Drug development fast Drugs / Structure-activity relationships fast Medizin Drugs / Structure-activity relationships Drug development Pharmakokinetik (DE-588)4115557-9 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
subject_GND | (DE-588)4115557-9 (DE-588)4143176-5 (DE-588)4143413-4 |
title | Molecular drug properties measurement and prediction |
title_auth | Molecular drug properties measurement and prediction |
title_exact_search | Molecular drug properties measurement and prediction |
title_full | Molecular drug properties measurement and prediction edited by Raimund Mannhold |
title_fullStr | Molecular drug properties measurement and prediction edited by Raimund Mannhold |
title_full_unstemmed | Molecular drug properties measurement and prediction edited by Raimund Mannhold |
title_short | Molecular drug properties |
title_sort | molecular drug properties measurement and prediction |
title_sub | measurement and prediction |
topic | Pharmaceutical Preparations / metabolism Chemistry, Pharmaceutical / methods Models, Molecular Pharmacokinetics Pharmacy Medicine MEDICAL / Pharmacology bisacsh Drug development fast Drugs / Structure-activity relationships fast Medizin Drugs / Structure-activity relationships Drug development Pharmakokinetik (DE-588)4115557-9 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
topic_facet | Pharmaceutical Preparations / metabolism Chemistry, Pharmaceutical / methods Models, Molecular Pharmacokinetics Pharmacy Medicine MEDICAL / Pharmacology Drug development Drugs / Structure-activity relationships Medizin Pharmakokinetik Arzneimittelentwicklung Aufsatzsammlung |
url | https://onlinelibrary.wiley.com/doi/book/10.1002/9783527621286 |
work_keys_str_mv | AT mannholdraimund moleculardrugpropertiesmeasurementandprediction |