The hERG cardiac potassium channel: structure, function, and long QT syndrome
Gespeichert in:
| Körperschaft: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Chichester, England
J. Wiley
2005
|
| Schriftenreihe: | Novartis Foundation symposium
266 |
| Schlagworte: | |
| Online-Zugang: | FRO01 UBG01 Volltext |
| Beschreibung: | Proceedings of the Symposium on The hERG Cardiac Potassium Channel: Structure, Function and Long QT Syndrome, held at Novartis Foundation, London, May 4-6, 2004. - Editors: Derek J. Chadwick, Jamie Goode Includes bibliographical references and indexes This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding.¡It features regulatory authority perspectives on preferred preclinical test systems and includes topics on¡hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks |
| Beschreibung: | 1 Online-Ressource (ix, 297 pages) |
| ISBN: | 0470021411 9780470021415 0470021403 9780470021408 047002142X 9780470021422 |
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| spelling | Symposium on The hERG Cardiac Potassium Channel: Structure, Function and Long QT Syndrome <2004, Novartis Foundation> Verfasser aut The hERG cardiac potassium channel structure, function, and long QT syndrome Chichester, England J. Wiley 2005 1 Online-Ressource (ix, 297 pages) txt rdacontent c rdamedia cr rdacarrier Novartis Foundation symposium 266 Proceedings of the Symposium on The hERG Cardiac Potassium Channel: Structure, Function and Long QT Syndrome, held at Novartis Foundation, London, May 4-6, 2004. - Editors: Derek J. Chadwick, Jamie Goode Includes bibliographical references and indexes This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding.¡It features regulatory authority perspectives on preferred preclinical test systems and includes topics on¡hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks Cardiac potassium channel hERG Conference papers and proceedings fast Potassium Channels, Voltage-Gated / Congresses / chemistry Potassium Channels, Voltage-Gated / Congresses / physiology Long QT Syndrome / Congresses / physiopathology Arrhythmia / Congresses MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Heart / Pathophysiology fast Heart / Physiology fast Long QT syndrome fast Potassium channels fast Medizin Potassium channels / Congresses Long QT syndrome / Congresses Heart / Physiology / Congresses Heart / Pathophysiology / Congresses Herzrhythmusstörung (DE-588)4024696-6 gnd rswk-swf Q-T-Syndrom (DE-588)4285371-0 gnd rswk-swf Kaliumkanal (DE-588)4258505-3 gnd rswk-swf (DE-588)1071861417 Konferenzschrift gnd-content Herzrhythmusstörung (DE-588)4024696-6 s Kaliumkanal (DE-588)4258505-3 s 1\p DE-604 Q-T-Syndrom (DE-588)4285371-0 s 2\p DE-604 Chadwick, Derek Sonstige oth Goode, Jamie Sonstige oth Novartis Foundation Sonstige oth https://onlinelibrary.wiley.com/doi/book/10.1002/047002142X Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | The hERG cardiac potassium channel structure, function, and long QT syndrome Cardiac potassium channel hERG Conference papers and proceedings fast Potassium Channels, Voltage-Gated / Congresses / chemistry Potassium Channels, Voltage-Gated / Congresses / physiology Long QT Syndrome / Congresses / physiopathology Arrhythmia / Congresses MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Heart / Pathophysiology fast Heart / Physiology fast Long QT syndrome fast Potassium channels fast Medizin Potassium channels / Congresses Long QT syndrome / Congresses Heart / Physiology / Congresses Heart / Pathophysiology / Congresses Herzrhythmusstörung (DE-588)4024696-6 gnd Q-T-Syndrom (DE-588)4285371-0 gnd Kaliumkanal (DE-588)4258505-3 gnd |
| subject_GND | (DE-588)4024696-6 (DE-588)4285371-0 (DE-588)4258505-3 (DE-588)1071861417 |
| title | The hERG cardiac potassium channel structure, function, and long QT syndrome |
| title_auth | The hERG cardiac potassium channel structure, function, and long QT syndrome |
| title_exact_search | The hERG cardiac potassium channel structure, function, and long QT syndrome |
| title_full | The hERG cardiac potassium channel structure, function, and long QT syndrome |
| title_fullStr | The hERG cardiac potassium channel structure, function, and long QT syndrome |
| title_full_unstemmed | The hERG cardiac potassium channel structure, function, and long QT syndrome |
| title_short | The hERG cardiac potassium channel |
| title_sort | the herg cardiac potassium channel structure function and long qt syndrome |
| title_sub | structure, function, and long QT syndrome |
| topic | Cardiac potassium channel hERG Conference papers and proceedings fast Potassium Channels, Voltage-Gated / Congresses / chemistry Potassium Channels, Voltage-Gated / Congresses / physiology Long QT Syndrome / Congresses / physiopathology Arrhythmia / Congresses MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Heart / Pathophysiology fast Heart / Physiology fast Long QT syndrome fast Potassium channels fast Medizin Potassium channels / Congresses Long QT syndrome / Congresses Heart / Physiology / Congresses Heart / Pathophysiology / Congresses Herzrhythmusstörung (DE-588)4024696-6 gnd Q-T-Syndrom (DE-588)4285371-0 gnd Kaliumkanal (DE-588)4258505-3 gnd |
| topic_facet | Cardiac potassium channel hERG Conference papers and proceedings Potassium Channels, Voltage-Gated / Congresses / chemistry Potassium Channels, Voltage-Gated / Congresses / physiology Long QT Syndrome / Congresses / physiopathology Arrhythmia / Congresses MEDICAL / Physiology SCIENCE / Life Sciences / Human Anatomy & Physiology Heart / Pathophysiology Heart / Physiology Long QT syndrome Potassium channels Medizin Potassium channels / Congresses Long QT syndrome / Congresses Heart / Physiology / Congresses Heart / Pathophysiology / Congresses Herzrhythmusstörung Q-T-Syndrom Kaliumkanal Konferenzschrift |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/047002142X |
| work_keys_str_mv | AT symposiumonthehergcardiacpotassiumchannelstructurefunctionandlongqtsyndrome2004novartisfoundation thehergcardiacpotassiumchannelstructurefunctionandlongqtsyndrome AT chadwickderek thehergcardiacpotassiumchannelstructurefunctionandlongqtsyndrome AT goodejamie thehergcardiacpotassiumchannelstructurefunctionandlongqtsyndrome AT novartisfoundation thehergcardiacpotassiumchannelstructurefunctionandlongqtsyndrome |