Vector targeting for therapeutic gene delivery:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, N.J.
John Wiley & Sons
2002
|
| Ausgabe: | 1st ed |
| Schlagworte: | |
| Online-Zugang: | FRO01 UBG01 Volltext |
| Beschreibung: | This title is available on the World Wide Web. Editions may vary. Access is restricted to computers located within Mount Sinai or to those users eligible for remote access services Includes bibliographical references and index The ability to deliver therapeutic genes effectively is the most important requirement for the success of gene therapy interventions. Representing the discipline's first authoritative text, Vector Targeting for Therapeutic Gene Delivery clearly presents the most recent advances in target definition technology and the principles underlying the rational design of targeted vectors for gene therapy. The book's first section focuses on transductional targeting strategies designed to achieve the selective delivery of the therapeutic gene by both nonviral and viral vectors; the second section discusses transcriptional targeting, in which the therapeutic gene is placed under the control of transcriptional regulatory sequences that are activated in the disease cells, but not in normal cells, and therefore target expression selectively to the tumor cell. Other sections consider the variety of strategies that can be employed to define appropriate cellular targeting moieties and strategies to monitor the extent of gene expression. This book also:*Provides a theoretical framework for advanced vector design*Integrates all of the allied sciences relevant to the study of vector targeting*Includes an expert's perspective on promising future therapeutic applicationsBiotechnology industry researchers, as well as individuals involved with the development of human gene therapies, will find Vector Targeting for Therapeutic Gene Delivery to be a vital addition to their professional libraries |
| Beschreibung: | 1 Online-Ressource (xviii, 710 pages) |
| ISBN: | 0471234303 9780471234302 1280556471 9781280556470 |
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| 245 | 1 | 0 | |a Vector targeting for therapeutic gene delivery |c edited by David T. Curiel, Joanne T. Douglas |
| 250 | |a 1st ed | ||
| 264 | 1 | |a Hoboken, N.J. |b John Wiley & Sons |c 2002 | |
| 300 | |a 1 Online-Ressource (xviii, 710 pages) | ||
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| 500 | |a This title is available on the World Wide Web. Editions may vary. Access is restricted to computers located within Mount Sinai or to those users eligible for remote access services | ||
| 500 | |a Includes bibliographical references and index | ||
| 500 | |a The ability to deliver therapeutic genes effectively is the most important requirement for the success of gene therapy interventions. Representing the discipline's first authoritative text, Vector Targeting for Therapeutic Gene Delivery clearly presents the most recent advances in target definition technology and the principles underlying the rational design of targeted vectors for gene therapy. The book's first section focuses on transductional targeting strategies designed to achieve the selective delivery of the therapeutic gene by both nonviral and viral vectors; the second section discusses transcriptional targeting, in which the therapeutic gene is placed under the control of transcriptional regulatory sequences that are activated in the disease cells, but not in normal cells, and therefore target expression selectively to the tumor cell. Other sections consider the variety of strategies that can be employed to define appropriate cellular targeting moieties and strategies to monitor the extent of gene expression. This book also:*Provides a theoretical framework for advanced vector design*Integrates all of the allied sciences relevant to the study of vector targeting*Includes an expert's perspective on promising future therapeutic applicationsBiotechnology industry researchers, as well as individuals involved with the development of human gene therapies, will find Vector Targeting for Therapeutic Gene Delivery to be a vital addition to their professional libraries | ||
| 650 | 4 | |a Pharmacology pharmaceutical medicine / Oncology / Pharmaceutical medicinal chemistry | |
| 650 | 4 | |a Gene Therapy / methods | |
| 650 | 4 | |a Genetic Vectors | |
| 650 | 4 | |a Gene Expression Regulation, Viral / genetics | |
| 650 | 4 | |a Transduction, Genetic / methods | |
| 650 | 7 | |a Gene targeting |2 fast | |
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| 650 | 7 | |a Genetic vectors |2 fast | |
| 650 | 4 | |a Gene therapy | |
| 650 | 4 | |a Gene targeting | |
| 650 | 4 | |a Genetic vectors | |
| 700 | 1 | |a Curiel, David |d 19XX- |e Sonstige |0 (DE-588)122647828X |4 oth | |
| 700 | 1 | |a Douglas, Joanne T. |e Sonstige |4 oth | |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:24:28Z |
| institution | BVB |
| isbn | 0471234303 9780471234302 1280556471 9781280556470 |
| language | English |
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| spelling | Vector targeting for therapeutic gene delivery edited by David T. Curiel, Joanne T. Douglas 1st ed Hoboken, N.J. John Wiley & Sons 2002 1 Online-Ressource (xviii, 710 pages) txt rdacontent c rdamedia cr rdacarrier This title is available on the World Wide Web. Editions may vary. Access is restricted to computers located within Mount Sinai or to those users eligible for remote access services Includes bibliographical references and index The ability to deliver therapeutic genes effectively is the most important requirement for the success of gene therapy interventions. Representing the discipline's first authoritative text, Vector Targeting for Therapeutic Gene Delivery clearly presents the most recent advances in target definition technology and the principles underlying the rational design of targeted vectors for gene therapy. The book's first section focuses on transductional targeting strategies designed to achieve the selective delivery of the therapeutic gene by both nonviral and viral vectors; the second section discusses transcriptional targeting, in which the therapeutic gene is placed under the control of transcriptional regulatory sequences that are activated in the disease cells, but not in normal cells, and therefore target expression selectively to the tumor cell. Other sections consider the variety of strategies that can be employed to define appropriate cellular targeting moieties and strategies to monitor the extent of gene expression. This book also:*Provides a theoretical framework for advanced vector design*Integrates all of the allied sciences relevant to the study of vector targeting*Includes an expert's perspective on promising future therapeutic applicationsBiotechnology industry researchers, as well as individuals involved with the development of human gene therapies, will find Vector Targeting for Therapeutic Gene Delivery to be a vital addition to their professional libraries Pharmacology pharmaceutical medicine / Oncology / Pharmaceutical medicinal chemistry Gene Therapy / methods Genetic Vectors Gene Expression Regulation, Viral / genetics Transduction, Genetic / methods Gene targeting fast Gene therapy fast Genetic vectors fast Gene therapy Gene targeting Genetic vectors Curiel, David 19XX- Sonstige (DE-588)122647828X oth Douglas, Joanne T. Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 0-471-43479-5 Erscheint auch als Druck-Ausgabe, Hardcover 978-0-471-43479-5 https://onlinelibrary.wiley.com/doi/book/10.1002/0471234303 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Vector targeting for therapeutic gene delivery Pharmacology pharmaceutical medicine / Oncology / Pharmaceutical medicinal chemistry Gene Therapy / methods Genetic Vectors Gene Expression Regulation, Viral / genetics Transduction, Genetic / methods Gene targeting fast Gene therapy fast Genetic vectors fast Gene therapy Gene targeting Genetic vectors |
| title | Vector targeting for therapeutic gene delivery |
| title_auth | Vector targeting for therapeutic gene delivery |
| title_exact_search | Vector targeting for therapeutic gene delivery |
| title_full | Vector targeting for therapeutic gene delivery edited by David T. Curiel, Joanne T. Douglas |
| title_fullStr | Vector targeting for therapeutic gene delivery edited by David T. Curiel, Joanne T. Douglas |
| title_full_unstemmed | Vector targeting for therapeutic gene delivery edited by David T. Curiel, Joanne T. Douglas |
| title_short | Vector targeting for therapeutic gene delivery |
| title_sort | vector targeting for therapeutic gene delivery |
| topic | Pharmacology pharmaceutical medicine / Oncology / Pharmaceutical medicinal chemistry Gene Therapy / methods Genetic Vectors Gene Expression Regulation, Viral / genetics Transduction, Genetic / methods Gene targeting fast Gene therapy fast Genetic vectors fast Gene therapy Gene targeting Genetic vectors |
| topic_facet | Pharmacology pharmaceutical medicine / Oncology / Pharmaceutical medicinal chemistry Gene Therapy / methods Genetic Vectors Gene Expression Regulation, Viral / genetics Transduction, Genetic / methods Gene targeting Gene therapy Genetic vectors |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/0471234303 |
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