Compendium of biophysics:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Beverly, MA, USA
Scrivener Publishing
2017
Hoboken, NJ, USA Wiley 2017 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | xvi, 641 Seiten Illustrationen, Diagramme, Portrait |
| ISBN: | 9781119160250 |
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Datensatz im Suchindex
| _version_ | 1804175911733428224 |
|---|---|
| adam_text | Contents
Introduction XV
PART I BIOPHYSICS OF COMPLEX SYSTEMS
I. Kinetics of Biological Processes 3
1 Qualitative Methods for Studying Dynamic Models of
Biological Processes 5
1.1 General Principles of Description of Kinetic Behavior of
Biological Systems 5
1.2 Qualitative Analysis of Elementary Models of Biological Processes 6
2 Types of Dynamic Behavior of Biological Systems 17
2.1 Biological Triggers 17
2.2 Oscillatory Processes in Biology. Limit Cycles 21
2.3 Time Hierarchy in Biological Systems 25
3 Kinetics of Enzyme Processes 29
3.1 Elementary Enzyme Reactions 29
3.2 Multiplicity of Stationary States in Enzyme Systems 35
3.3 Oscillations in Enzyme Systems 37
3.4 Mathematical Modeling of Metabolic Pathways 39
4 Self-Organization Processes in Distributed Biological Systems 45
4.1 General Characteristics of Autowave Processes 45
4.2 Mathematical Models of Self-Organized Structures 47
4.3 Chaotic Processes in Determined Systems 60
II. Thermodynamics of Biological Processes 77
5 Thermodynamics of Irreversible Processes in Biological Systems
Near Equilibrium (Linear Thermodynamics) 79
6 Thermodynamics of Systems Far From Equilibrium
(Nonlinear Thermodynamics) 91
V
vi Contents
PART II MOLECULAR BIOPHYSICS
III. Three-dimensional Organization of Biopolymers 99
7 Three-dimensional Configurations of Polymer Molecules 101
7.1 Statistical Character of Polymer Structure 101
7.2 Volumetric Interactions and Globule -Coil Transitions in Polymer
Macromolecules 102
7.3 Phase Transitions in Proteins 105
8 Different Types of Interactions inMacromolecules 109
8.1 Van-der-Waals Interactions 110
8.2 Hydrogen Bond. Charge -Dipole Interactions 113
8.3 Internal Rotation and Rotational Isomerism 114
9 Conformational Energy and Three-dimensional Structure of Biopolymers 117
9.1 Conformational Energy of Polypeptide Chains 117
9.2 Numerical Methods for Estimation of Conformational
Energy of Biopolymers 121
9.3 Predictions of Three-dimensional Structure of Proteins 124
9.4 Peculiarities of Three-dimensional Organization of Nucleic Acids 131
9.5 State of Water and Hydrophobic Interactions in Biostructures 138
9.6 Protein Folding 146
IV. Dynamic Properties of Globular Proteins 153
10 Protein Dynamics 155
10.1 Structural Changes in Proteins 155
10.2 Conformational Mobility of Proteins by the Data of Different Methods 157
11 Physical Models of Dynamic Mobility of Proteins 187
11.1 General Characteristic of Molecular Dynamics of Biopolymers 187
11.2 Model of Limited Diffusion (Brownian Oscillator with Strong Damping) 190
11.3 Numerical Modeling of Molecular Dynamics of Proteins 198
11.4 Molecular Dynamics of Protein Myoglobin 206
11.5 Dynamic Models of DNA 210
11.6 Direct Modeling of Interactions of Proteins 218
Further Reading 223
PART III BIOPHYSICS OF MEMBRANE PROCESSES
V. Structure-functional Organization of Biological Membranes 227
12 Molecular Organization of Biological Membranes 229
12.1 Composition and Structure of Biological Membranes 229
12.2 Formation of Membrane Structures 231
Contents ѵіі
12.3 Thermodynamics of Membrane Formation and Stability 234
12.4 Mechanical Properties of Membranes 236
12.5 Effect of Electric Fields on Cells 243
13 Conformational Properties of Membranes 247
13.1 Phase Transitions in Membrane Systems 247
13.2 Lipid - Lipid Interactions in Membranes 251
13.3 Lipid - Protein and Protein - Protein Interactions in Membranes 253
13.4 Peroxidation of Biomembrane Lipids 255
VI. Transport of Substances and Bioelectrogenesis 261
14 Nonelectrolyte Transport 263
14.1 Diffusion 263
14.2 Facilitated Diffusion 265
14.3 Water Transport. Aquaporins 267
15 Ion Transport.Ionic Equilibria 269
15.1 Electrochemical Potential 269
15.2 Ion Hydration 270
15.3 Ionic Equilibrium on the Phase Interface 271
15.4 Profiles of Potential and Concentrations at the Interface 274
15.5 Double Electric Layer 277
16 Electrodiffusion Theory of Ion Transport Across Membranes 281
16.1 The Nernst - Planck Equation of Electrodiffusion 281
16.2 Constant Field Approximation 282
17 Induced Ion Transport 287
17.1 Bilayer Lipid Membranes 287
17.2 Mobile Carriers 288
17.3 Channel-forming Reagents 290
17.4 Effect of Surface and Dipole Potentials on the Ion Transport Rate 292
18 Ion Transport in Channels 295
18.1 Discrete Description of Transport 295
18.2 Channel Blocking and Saturation 298
18.3 General Properties of Ion Channels in Nervous Fibers 300
18.4 Molecular Structure of Channels 302
18.5 Electric Fluctuations of Membrane Properties 311
19 Ion Transport in Excitable Membranes 319
19.1 Action Potential 319
19.2 Ion Currents in the Axon Membrane 321
19.3 Description of Ionic Currents in the Hodgkin -Huxley Model 325
19.4 Gating Currents 330
19.5 Impulse Propagation 334
viii Contents
20 Active Transport 339
20.1 Calcium Pump 340
20.2 Sodium-Potassium Pump 343
20.3 Electrogenic Ion Transport 345
20.4 Proton Transport 347
VII. Energy Transformation in Biomembranes 349
21 Electron Transport and Energy Transformation in Biomembranes 351
21.1 General Description of Energy Transformation in Biomembranes 351
21.2 Mechanisms of Proton Translocation and Generation of À/ÏH+ in
Respiratory and Photosynthetic Chains of Electron Transport 353
21.3 ATPase Complex 354
21.4 ATPase Complex as a Molecular Motor 359
22 Physics ofMuscle Contraction, Actin-Myosin Molecular Motor 365
22.1 General Description of Energy Transformation in Systems of
Biological Motility 365
22.2 Basic Information on Properties of Cross-striated Muscles 366
22.3 Structural Organization of Muscle Contractile and Regulatory
Proteins 370
22.4 Mechanochemical Transformation of Energy in Muscles.
Lymn - Taylor Scheme 373
22.5 Three-dimensional Structure of Actin and the Myosin Head 375
22.6 Mechanism of the Work Cycle of the Actin-Myosin Motor 376
23 Biophysics of Processes of Intracellular Signaling 379
23.1 General Regularities of Intracellular Signaling 379
23.2 Biophysics of Cellular Signaling 382
23.3 Methods for Studying Cell Signaling 386
Further Reading 402
VIII. Electronic Properties of Biopolymers 403
24 Fundamentals of Quantum Description of Molecules 405
24.1 Introduction 405
24.2 Stationary and Non-stationary States of Quantum Systems.
Principle of Superposition of States 407
24.2.1 Harmonic Oscillator 409
24.2.2 Normal Coordinates and Normal Frequencies of a
System of Coupled Oscillators 410
24.3 Theory of Non-stationary Excitations — Theory of Transitions 412
24.4 Model of a Hydrogen Molecule Ion. Nature of Chemical Bonds 414
24.5 Method of Molecular Orbitals 417
24.6 Manifestation of Electronic Properties of Biopolymers 419
Contents ix
25 Mechanisms of Charge Transfer and Energy Migration in
Biomolecular Structures 425
25.1 Tunneling Effect 428
25.1.1 Quasi-classical Approximation. The Gamow Formula 428
25.1.2 Calculation of Transmittance of Potential Barriers 431
25.1.3 Adiabatic Approximation 434
25.2 The Charge Transfer Theory 441
25.2.1 Formulation of the Problem. Localized States 441
25.2.2 Electron-vibrational Interactions 442
25.2.3 Decay of Excited State of Quantum Systems 450
25.2.4 Analysis of the Temperature Dependence of the
Electron Transfer 451
25.2.5 General Analysis of Jortner and Marcus Formulas 456
25.3 Role of Hydrogen Bonds in Electron Transport in
Biomolecular Systems 462
25.4 Dynamics of Photoconformational Transfer 464
25.5 Mechanisms of Energy Migration 472
25.5.1 Inductive Resonance Mechanism 472
25.5.2 Exchange Resonance Energy Transfer 476
25.5.3 Exciton Mechanism 478
26 Mechanisms of Enzyme Catalysis 481
26.1 Physicochemical Description and Biophysical Models of
Enzyme Processes 481
26.2 Electron Conformational Interactions upon Enzyme Catalysis 487
26.3 Electronic Interactions in the Enzyme Active Center 492
26.4 Molecular Modeling of the Structure of an
Enzyme - Substrate Complex 496
IX. Primary Processes of Photosynthesis 503
27 Energy Transformation in Primary Processes of Photosynthesis 505
27.1 General Characteristic of Initial Stages of Photobiological Processes 505
27.2 General Scheme of Primary Processes of Photosynthesis 508
27.3 Structural Organization of Pigment - Protein Antenna Complexes 513
27.4 Mechanisms of Transformation of Excitation Energy in
Photosynthetic Membrane 515
27.5 Reaction Centers in Purple Photosynthesizing Bacteria 522
27.6 Pigment - Protein Complex of Photosystem I 529
27.7 Pigment - Protein Complex of Photosystem II 532
27.8 Variable and Delayed Fluorescence 538
28 Electron-Conformational Interactions in Primary Processes
of Photosynthesis 547
28.1 Studies of Superfast Processes in Reaction Centers of Photosynthesis 548
28.2 Initial Charge Separation in RCs 559
X Contents
28.3 Mechanisms of Cytochrome Oxidation in Reaction Centers 563
28.4 Conformational Dynamics and Electron Transfer in Reaction Centers 566
28.5 Electron Transfer and Formation of Contact States in the
System of Quinone Acceptors (PQA QB) 568
28.6 Mathematical Models of Primary Electron Transport Processes in
Photosynthesis 571
X. Primary Processes in Biological Systems 579
29 Photo-conversions of Bacteriorhodopsin and Rhodopsin 581
29.1 Structure and Functions of Purple Membranes 582
29.2 Photocycle of Bacteriorhodopsin 585
29.3 Primary Act of Bacteriorhodopsin Photoconversions 589
29.4 Model Systems Containing Bacteriorhodopsin 592
29.5 Molecular Bases of Visual Reception. Visual Cells (Rods) 594
29.6 Primary Act of Rhodopsin Photoconversion 599
30 Photoregulatory and Photodestructive Processes 607
30.1 General Characteristics of Photoregulatory Processes 607
30.2 Photoreceptors and Molecular Mechanisms of Photoregulatory
Processes. Phytochromes 608
30.3 General Characteristics of Photodestructive Processes 615
30.4 Photochemical Reactions in DNA and Its Components 617
30.5 Effects of High-intensity Laser UV Irradiation on DNA
(Twoquantum Reactions) 620
30.6 Photoreactivation and Photoprotection 621
30.7 Ultraviolet Light Action on Proteins 623
30.8 Sensitized Damage of Biomolecules in Photodynamic Reactions 625
30.9 Photosensitized Effects in Cell Systems 629
Further Reading 633
Index 635
The most thorough coverage of biophysics available, in a handy, easy-
to-read volume, perfect as a reference for experienced engineers or as a
textbook for the novice.
Following up on his first book, Fundamentals of Biophysics, the author, a well-known scientist
in this area, builds on that foundation by offering the biologist or scientist an advanced,
comprehensive coverage of biophysics. Structuring the book into four major parts, he
thoroughly covers the biophysics of complex systems, such as the kinetics and thermodynamic
processes of biological systems, in the first part. The second part is dedicated to molecular
biophysics, such as biopolymers and proteins, and the third part is on the biophysics of
membrane processes. The final part is on photobiological processes.
This ambitious work is a must-have for the veteran biologist, scientist, or chemist working
in this field, and for the novice or student, who is interested in learning about biophysics. It
is an emerging field, becoming increasingly more important, the more we learn about and
develop the science. No’library on biophysics is complete without this text and its precursor,
both available from Wiley-Scrivener.
This outstanding new volume:.
• Presents a thorough and in-depth coverage of the fundamental theory and practical
applications of biophysics, providing the most up-to-date research available
• Is structured into four parts, covering the four major areas in biophysics
• Covers new and emerging topics in biophysics, including more advanced topics
• Is written by one of the world s foremost authorities on the topic, and is the best
textbook available, following up on his first book on the fundamentals of biophysics,
available from Wiley-Scrivener
Andrey B. Rubin is a professor of biophysics at Lomonosov Moscow State University in
the Department of Biophysics. Born in Russia, he is chair of the National Committee for
Biophysics in the Russian Academy of Science. He has been head of the Department of
Biophysics at MSU, Governor of the Task Force on Education in Biophysics, and a member of
the RAS Council on Space Biology and Biological Membranes since 2005. He has received
many awards for his contributions to the science of biophysics, and he holds many patents
and inventions, as well as having been the author of numerous papers. He is also on the
editorial board of the journal, Biophysics, in the Russian language.
Cover Design: Kris Hackerott
Cover Image (3D Interferon Gamma): ibreakstock | Dreamstime.com
Also available
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|
| any_adam_object | 1 |
| author | Rubin, Andrey B. 1937- |
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| discipline | Biologie |
| format | Book |
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| id | DE-604.BV043355268 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:23:49Z |
| institution | BVB |
| isbn | 9781119160250 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028774643 |
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| publishDate | 2017 |
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| spelling | Rubin, Andrey B. 1937- Verfasser (DE-588)1061057585 aut Compendium of biophysics Andrey B. Rubin Beverly, MA, USA Scrivener Publishing 2017 Hoboken, NJ, USA Wiley 2017 xvi, 641 Seiten Illustrationen, Diagramme, Portrait txt rdacontent n rdamedia nc rdacarrier Gewässerschutz (DE-588)4020830-8 gnd rswk-swf Grundwassersanierung (DE-588)4510696-4 gnd rswk-swf Biophysik (DE-588)4006891-2 gnd rswk-swf Grundwasserschutz (DE-588)4022376-0 gnd rswk-swf Grundwasser (DE-588)4022369-3 gnd rswk-swf Biophysik (DE-588)4006891-2 s DE-604 Grundwasser (DE-588)4022369-3 s Grundwassersanierung (DE-588)4510696-4 s Gewässerschutz (DE-588)4020830-8 s Grundwasserschutz (DE-588)4022376-0 s Digitalisierung UB Bayreuth - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028774643&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Bayreuth - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028774643&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Rubin, Andrey B. 1937- Compendium of biophysics Gewässerschutz (DE-588)4020830-8 gnd Grundwassersanierung (DE-588)4510696-4 gnd Biophysik (DE-588)4006891-2 gnd Grundwasserschutz (DE-588)4022376-0 gnd Grundwasser (DE-588)4022369-3 gnd |
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| title | Compendium of biophysics |
| title_auth | Compendium of biophysics |
| title_exact_search | Compendium of biophysics |
| title_full | Compendium of biophysics Andrey B. Rubin |
| title_fullStr | Compendium of biophysics Andrey B. Rubin |
| title_full_unstemmed | Compendium of biophysics Andrey B. Rubin |
| title_short | Compendium of biophysics |
| title_sort | compendium of biophysics |
| topic | Gewässerschutz (DE-588)4020830-8 gnd Grundwassersanierung (DE-588)4510696-4 gnd Biophysik (DE-588)4006891-2 gnd Grundwasserschutz (DE-588)4022376-0 gnd Grundwasser (DE-588)4022369-3 gnd |
| topic_facet | Gewässerschutz Grundwassersanierung Biophysik Grundwasserschutz Grundwasser |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028774643&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028774643&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT rubinandreyb compendiumofbiophysics |