Holdings: Arsenic species analysis in foods and biota

Arsenic species analysis in foods and biota:

Saved in:

Bibliographic Details
Main Author:	Lischka, Susanne (Author)
Format:	Thesis Book
Language:	English
Published:	Berlin 2015
Subjects:	Chemische Analyse Arsenverbindungen Hochschulschrift
Online Access:	Inhaltsverzeichnis
Physical Description:	XIV, 135 Seiten Illustrationen, Diagramme (teilweise farbig)

Staff View

MARC


LEADER	00000nam a2200000 c 4500
001	BV043340416
003	DE-604
005	20221201
007	t
008	160204s2015 a\|\|\| m\|\|\| 00\|\|\| eng d
035			\|a (OCoLC)951598959
035			\|a (DE-599)BVBBV043340416
040			\|a DE-604 \|b ger \|e rda
041	0		\|a eng
049			\|a DE-11
084			\|a VG 6807 \|0 (DE-625)147192:260 \|2 rvk
084			\|a VK 7723 \|0 (DE-625)147445: \|2 rvk
100	1		\|a Lischka, Susanne \|e Verfasser \|0 (DE-588)1082051993 \|4 aut
245	1	0	\|a Arsenic species analysis in foods and biota \|c von Dipl.-Chem. Susanne Lischka
264		1	\|a Berlin \|c 2015
300			\|a XIV, 135 Seiten \|b Illustrationen, Diagramme (teilweise farbig)
336			\|b txt \|2 rdacontent
337			\|b n \|2 rdamedia
338			\|b nc \|2 rdacarrier
502			\|b Dissertation \|c Humboldt-Universität zu Berlin \|d 2015
650	0	7	\|a Chemische Analyse \|0 (DE-588)4009840-0 \|2 gnd \|9 rswk-swf
650	0	7	\|a Arsenverbindungen \|0 (DE-588)4143104-2 \|2 gnd \|9 rswk-swf
655		7	\|0 (DE-588)4113937-9 \|a Hochschulschrift \|2 gnd-content
689	0	0	\|a Arsenverbindungen \|0 (DE-588)4143104-2 \|D s
689	0	1	\|a Chemische Analyse \|0 (DE-588)4009840-0 \|D s
689	0		\|8 1\p \|5 DE-604
776	0	8	\|i Reproduziert als \|a Lischka, Susanne \|t Arsenic species analysis in foods and biota \|d Ketsch bei Mannheim : Mikroform Dissertation, 2015 \|h 2 Mikrofiches \|w (DE-604)BV043633907
856	4	2	\|m DNB Datenaustausch \|q application/pdf \|u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028760331&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA \|3 Inhaltsverzeichnis
999			\|a oai:aleph.bib-bvb.de:BVB01-028760331
883	1		\|8 1\p \|a cgwrk \|d 20201028 \|q DE-101 \|u https://d-nb.info/provenance/plan#cgwrk

Record in the Search Index

_version_	1804175890928631808
adam_text	CONTENT ZUSAMMENFASSUNG ABSTRACT................................................................................................................................................. II ACKNOWLEDGEMENTS ...................................... ILL LIST O F FIGURES................................................................................................................................... VII LIST O F TABLES......................................................................................................................................IX ABBREVIATIONS................................................................................................................................... XII 1. INTRODUCTION AND SCOPE O F 1 1.1 BACKGROUND AND MOTIVATION....................................................................................................1 1.2 SCOPE OF THE PRESENT ........................................ 6 2. LITERATURE REVIEW............................................................................................................................. 9 2.1 CLASSES * TOXICITY AND METABOLIC PATHWAYS O F ARSENIC SPECIES ............................................ 9 2.1.1 TOXIC * POLAR A R S E N I C A L S 9 2.1.2 NON-TOXIC POLAR ARSENICALS.......................................................................................13 2.13 ARSENOSUGARS........................................... 14 2.1.4 NON-POLAR ARSENICALS - ARSENOLIPIDS AND ARSENOHYDROCARBONS.......................... 15 2.2 SOURCES O F ARSENIC FOT HUMANS............................................................................................. 18 2.3 RELEVANCE O F ARSENIC IN GOVERNMENTAL REGULATION ............................................................. 20 2.4 CERTIFIED MATRIX REFERENCE MATERIALS CONCERNING ORGANOARSENIC SPECIES 22 2.5 STABILITY OF ARSENIC SPECIES...................................................................................................24 2.6 PROPERTIES 01 ISOTOPE LABELLED INTERNAL STANDARDS .............................................................. 28 2.7 ANALYTICAL METHODS FOR THE DETEMI^^ 30 2.7.1 SAMPLE PRE-TREATMENT...............................................................................................33 2.7.2 NEUTRON ACTIVATION ANALYSIS..................................................................................... 34 2.7.3 TOTAL REFLECTION X-RAY FLUORESCENCE SPECTROSCOPY ................................................ 35 2.7.4 ICP-MS ** 2.7.5 HPLC-ICP-MS......................................................................................................... 37 2.7.6 HPLC-ESI-MSMS..................................................................................................38 2.7.7 HPLC-ESI-Q-TOF-MS ........................................................................................... 39 2.7.8 GC-EI-MS ............................................................................................................ 40 2.7.9 SUMMARY................................................................................................................... 41 3 MATERIALS AND METHODS................................................................................................................. 4 * 3.1 MATERIALS ............................................................................................................................... 4 * 3.1.1 CHEMICALS.................................................................................................................. 43 3.1.2 CONSUMABLES AND ANALYTICAL INSTRUMENTS .............................................................. 43 3.2 METHODS 3.2.1 SYNTHESIS O F TWOFOLD ^-LABELLED ARSENOBETAINE ................................................. 45 3.2.2 CHARACTERISATION OF ARSENOBETAINE STANDARD MATERIALS.......................................... 46 3.2.3 PRODUCTION OI -HOUSE FISH MATERIAL......................................................................48 3.2.4 EXTRACTION AND CLEANUP PROTOCOL FOR POLAR ORGANOARSENICALS............................. 49 3.2.5 SPECIES-SPECIFIC ANALYSIS USING HPLCICP-MS...................................................50 3.2.6 DETERMINATION OF TOTAL ARSENIC CONTENT USING ICP-MS ......................................... 51 3.2.7 DETEMIINATIONOFTOTAL ARSENIC CONTENT USING TXRF ............................................ 2 3.2.8 DETERMINATION OF LIPOPHILIC AND HYDROPHILIC ARSENIC BY TXRF........................ 52 3.2.9 EXACT MASS MEASUREMENTS WITH ICP-MS/ESI-Q-TOF-MS *****53 3.2.10 DETERMINATION OF ARSENIC SPECIES USING GC-EI-MS.............................................53 3.2.11 DETERMINATION O F ARSENOBETAINE USING HPLC-ESI-MS/MS ******54 3.2.12 ENZYMATIC ASSAYS......................................................................................................55 4. RESULTS AND DISCUSSION_^^ 4.1 CHARACTERISTICS OF THE MARINE FISH UNDER INVESTIGATION.....................................................58 4.2 COMPILATION OF SAMPLE PRE-TREATMENT CONDITIONS ............................................................. 60 4.2.1 PLE EXTRACTION..........................................................................................................60 4.2.2 UTOASONIC ASSISTED EXTRACTION^ 4.3 ARSENOM O F INVESTIGATED F I S H ....................................... ..................................... 65 4.3.1 POLAR ARSENIC SPECIES................................................................................................ 68 4.3.2 NON-POLAR ARSENIC SPECIES........................................................................................70 4.4 DETERMINATION OFARSENIC SPECIES USING GC-MS .............................................................. 82 4.5 CHARACTERISATION OF ARENOBETAINE STANDARD MATERIAL ........................................................ 89 4.6 VALIDATION OF THE ARSENOBETAI^^ 93 4.6.1 WORKING RANGE AND TESTED MATRICES.........................................................................94 4.6.2 INTERFERENCES............................................................................................................. 94 4.6.3 SAMPLE STABILITY........................................................................................................95 4.6.4 CHROMATOGRAPHIC SEPARATION................................................................................... 95 4.6.5 FIGURES OFMERIT FOR THE VALIDATED 97 4.6.6 ACCURACY AND PRECISION...........................................................................................98 4.6.7 RUGGEDNESS AND ROBUSTOESS.................................................................................... 98 4.6.8 UNCERTAINTY OF MEASUREMENT.................................................................................. 99 4.7 STABILITY O F IN-HOUSE H ED N G M A T E .............................................................................. 100 4.8 EXAMPLES FOR THE CAPABILITY O F THE VALIDATED M ETHOD .................................................... 105 4.8.1 CCQM-P96.1 PILOT STUDY............................................. ..............................105 4.8.2 ENZYMATIC EXPERIMENTS......................................................................................... 106 4.8.3 INVESTIGATION OF POLAR ARSENICAL IN SURSTROEMMING.............................................109 5. CONCLUSION................................................................................................................................... I LL 6. RECOMMENDATIONS FOR FUTURE RESEARCH.................................................................. ******115 BIBLIOGRAPHY..................................................................................................................................... 121 APPENDIX.......................................................................................................................................... 127
any_adam_object	1
author	Lischka, Susanne
author_GND	(DE-588)1082051993
author_facet	Lischka, Susanne
author_role	aut
author_sort	Lischka, Susanne
author_variant	s l sl
building	Verbundindex
bvnumber	BV043340416
classification_rvk	VG 6807 VK 7723
ctrlnum	(OCoLC)951598959 (DE-599)BVBBV043340416
discipline	Chemie / Pharmazie
format	Thesis Book
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01744nam a2200385 c 4500</leader><controlfield tag="001">BV043340416</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20221201 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">160204s2015 a\|\|\| m\|\|\| 00\|\|\| eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)951598959</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043340416</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-11</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VG 6807</subfield><subfield code="0">(DE-625)147192:260</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VK 7723</subfield><subfield code="0">(DE-625)147445:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Lischka, Susanne</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1082051993</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Arsenic species analysis in foods and biota</subfield><subfield code="c">von Dipl.-Chem. Susanne Lischka</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Berlin</subfield><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XIV, 135 Seiten</subfield><subfield code="b">Illustrationen, Diagramme (teilweise farbig)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="502" ind1=" " ind2=" "><subfield code="b">Dissertation</subfield><subfield code="c">Humboldt-Universität zu Berlin</subfield><subfield code="d">2015</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Chemische Analyse</subfield><subfield code="0">(DE-588)4009840-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Arsenverbindungen</subfield><subfield code="0">(DE-588)4143104-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4113937-9</subfield><subfield code="a">Hochschulschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Arsenverbindungen</subfield><subfield code="0">(DE-588)4143104-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Chemische Analyse</subfield><subfield code="0">(DE-588)4009840-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">1\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Reproduziert als</subfield><subfield code="a">Lischka, Susanne</subfield><subfield code="t">Arsenic species analysis in foods and biota</subfield><subfield code="d">Ketsch bei Mannheim : Mikroform Dissertation, 2015</subfield><subfield code="h">2 Mikrofiches</subfield><subfield code="w">(DE-604)BV043633907</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">DNB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028760331&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-028760331</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield></record></collection>
genre	(DE-588)4113937-9 Hochschulschrift gnd-content
genre_facet	Hochschulschrift
id	DE-604.BV043340416
illustrated	Illustrated
indexdate	2024-07-10T07:23:29Z
institution	BVB
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-028760331
oclc_num	951598959
open_access_boolean
owner	DE-11
owner_facet	DE-11
physical	XIV, 135 Seiten Illustrationen, Diagramme (teilweise farbig)
publishDate	2015
publishDateSearch	2015
publishDateSort	2015
record_format	marc
spelling	Lischka, Susanne Verfasser (DE-588)1082051993 aut Arsenic species analysis in foods and biota von Dipl.-Chem. Susanne Lischka Berlin 2015 XIV, 135 Seiten Illustrationen, Diagramme (teilweise farbig) txt rdacontent n rdamedia nc rdacarrier Dissertation Humboldt-Universität zu Berlin 2015 Chemische Analyse (DE-588)4009840-0 gnd rswk-swf Arsenverbindungen (DE-588)4143104-2 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Arsenverbindungen (DE-588)4143104-2 s Chemische Analyse (DE-588)4009840-0 s 1\p DE-604 Reproduziert als Lischka, Susanne Arsenic species analysis in foods and biota Ketsch bei Mannheim : Mikroform Dissertation, 2015 2 Mikrofiches (DE-604)BV043633907 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028760331&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk
spellingShingle	Lischka, Susanne Arsenic species analysis in foods and biota Chemische Analyse (DE-588)4009840-0 gnd Arsenverbindungen (DE-588)4143104-2 gnd
subject_GND	(DE-588)4009840-0 (DE-588)4143104-2 (DE-588)4113937-9
title	Arsenic species analysis in foods and biota
title_auth	Arsenic species analysis in foods and biota
title_exact_search	Arsenic species analysis in foods and biota
title_full	Arsenic species analysis in foods and biota von Dipl.-Chem. Susanne Lischka
title_fullStr	Arsenic species analysis in foods and biota von Dipl.-Chem. Susanne Lischka
title_full_unstemmed	Arsenic species analysis in foods and biota von Dipl.-Chem. Susanne Lischka
title_short	Arsenic species analysis in foods and biota
title_sort	arsenic species analysis in foods and biota
topic	Chemische Analyse (DE-588)4009840-0 gnd Arsenverbindungen (DE-588)4143104-2 gnd
topic_facet	Chemische Analyse Arsenverbindungen Hochschulschrift
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028760331&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT lischkasusanne arsenicspeciesanalysisinfoodsandbiota

Holdings

There is no print copy available.

Interlibrary loan Place Request Caution: Not in THWS collection! Indexes

MARC

Record in the Search Index

There is no print copy available.

Similar Items