Basement membranes:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier ; Academic Press
2015
|
| Ausgabe: | First edition |
| Schriftenreihe: | Current topics in membranes
volume 76 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVIII, 386 Seiten, 11 ungezählte Blätter Illustrationen |
| ISBN: | 9780128040157 |
Internformat
MARC
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| 250 | |a First edition | ||
| 264 | 1 | |a Amsterdam |b Elsevier ; Academic Press |c 2015 | |
| 300 | |a XVIII, 386 Seiten, 11 ungezählte Blätter |b Illustrationen | ||
| 336 | |b txt |2 rdacontent | ||
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| 338 | |b nc |2 rdacarrier | ||
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Datensatz im Suchindex
| _version_ | 1804175829856419840 |
|---|---|
| adam_text | CONTENTS
Contributors lx
Preface xi
Previous Volumes In Series xv
1. Integrating Activities of Laminins that Drive Basement Membrane
Assembly and Function 1
Peter D. Yurchenco
1. Introduction 2
2. The Laminin Family 2
3. Laminin Polymerization 5
4. Laminin Adhesion to Cell Surfaces and Anchorage to Cytoskeieton 9
5. Laminin Polymerization on Cell Surfaces 13
6. Adaptor Proteins that Bind to Laminins: Nidogen, Perlecan, and Agrin 14
7. Type IV Collagen Network 15
8. Laminin-Deficient Muscular Dystrophy and Neuropathy 16
9. Pierson Syndrome 20
10. Conclusions 22
Acknowledgments 24
References 24
2. Laminin-a2 Chain-Deficient Congenital Muscular Dystrophy:
Pathophysiology and Development of Treatment 31
Madeleine Durbeej
1. Introduction 32
2. Laminin-211 and Cell Surface Receptors 32
3. Clinical Phenotype of MDC1A 36
4. Animal Models of MDC1A 38
5. Pathogenesis of MDC 1A 39
6. Amelioration of Disease in Mice 44
7. Conclusion 51
Acknowledgments 52
References 52
v
VI
Contents
3. Type IV Collagens and Basement Membrane Diseases:
Cell Biology and Pathogenic Mechanisms 61
Mao Mao, Marcel V. Alavi, Cassandre Labelle-Dumais, Douglas B. Gould
1. Genomic Organization and Protein Structure of Type IV Collagens 62
2. Type IV Collagen Biosynthesis 72
3. Type IV Collagen-Related Pathology 78
4. Mechanisms for Type IV Collagen-Related Pathology 86
References 95
4. Epidermal Basement Membrane in Health and Disease 117
Cristina Has, Alexander Nyström
1. introduction 118
2. Composition and Architecture of the Epidermal BM and Associated
Adhesion Structures 119
3. The Role of Components of the Epidermal BM in Cutaneous Regeneration 141
4. Disorders of the Epidermal BM 147
5. Conclusions and Future Prospects 154
Acknowledgments 154
References 154
5, Applying Proteomics to Investigate Extracellular Matrix in
Health and Disease 171
Michael Randles, Rachel Lennon
1. introduction 172
2. Mass Spectrometry-Based Proteomics 174
3. Enrichment of ECM for Proteomic Analysis 179
4. Defining the Matrisome 180
5. Proteomics of ECM in Health and Disease 182
6. Emerging Techniques 189
7. Summary 193
References 193
6, Molecular Basis of Laminin-lntegrin Interactions 197
Masashi Yamada, Kiyotoshi Sekiguchi
1. introduction 198
2. Laminin Receptors 201
3. Ligand Specificities of Laminin-Binding Integrins 203
4. Mechanisms Underlying the Recognition of Laminins by Integrins 205
Contents
vîi
5. Molecular Mechanisms of Laminin Action through Integrins 211
6. The Roles of Tetraspanins in the Regulation of Laminin-Binding Integrins 214
7. Conclusions 219
Acknowledgments 219
References 219
7. Cell Receptor-Basement Membrane Interactions in Health and
Disease: A Kidney-Centric View 231
Corina M. Borza, Xiwu Chen, Roy Zent, Ambra Pozzi
1. Basement Membrane Components in Healthy and Diseased Kidney 232
2. The Alport Mouse Models of Kidney Disease 233
3. Laminins and Mouse Models of Glomerular Kidney Disease 235
4. Laminins and Renal Epithelial Cell Homeostasis 237
5. Nidogens and Heparan Sulfate Proteoglycans in Kidney Homeostasis 237
6. Basement Membrane Modifying Enzymes in Health and Disease 238
7. Integrins in Healthy and Diseased Kidney 238
8. Conclusions 247
Acknowledgments 247
References 247
8. The Basement Membrane Proteoglycans Perlecan and Agrin:
Something Old, Something New 255
Kevin J. McCarthy
1. Introduction 256
2. A Succinct Historical Perspective 257
3. Basement Membrane Proteoglycan Core Proteins 263
References 286
9. Building from the Ground up: Basement Membranes in
Drosophila Development 305
Adam J. Isabella, Sally Horne-Badovinac
1. Introduction 306
2. Synthesis, Secretion, and Assembly of BMs on Basal Cell Surfaces 308
3. Mechanical Contributions of the BM to Morphogenesis 317
4. Contributions of the BM to Cell-Cell Signaling during Development 323
5. Conclusion 328
Acknowledgments 328
References 329
Contents
viii
10. Basement Membranes in the Worm: A Dynamic Scaffolding
that Instructs Cellular Behaviors and Shapes Tissues 337
Matthew R. Clay, David R. Sherwood
1. Introduction 338
2. Basement Membrane Assembly in the Worm: Diverse Compositions
Determined by Local Interactions and Recruitment of Matrix Components 341
3. Basement Membranes Instruct Diverse Cellular Behaviors and Shape Tissues 344
4. Creating Gaps in—or Links between—Basement Membranes Helps
Shape Tissues 354
5. Future Directions and Perspectives 361
6. Conclusion 363
Acknowledgments 364
References 364
index 373
|
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| id | DE-604.BV043297223 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:22:31Z |
| institution | BVB |
| isbn | 9780128040157 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028718196 |
| oclc_num | 936136626 |
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| physical | XVIII, 386 Seiten, 11 ungezählte Blätter Illustrationen |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | Elsevier ; Academic Press |
| record_format | marc |
| series | Current topics in membranes |
| series2 | Current topics in membranes |
| spelling | Basement membranes edited by Jeffrey H. Miner (Washington University , St. Louis, MO, USA) First edition Amsterdam Elsevier ; Academic Press 2015 XVIII, 386 Seiten, 11 ungezählte Blätter Illustrationen txt rdacontent n rdamedia nc rdacarrier Current topics in membranes volume 76 Basalmembran (DE-588)4144086-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Basalmembran (DE-588)4144086-9 s b DE-604 Miner, Jeffrey edt Current topics in membranes volume 76 (DE-604)BV036839511 76 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028718196&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Basement membranes Current topics in membranes Basalmembran (DE-588)4144086-9 gnd |
| subject_GND | (DE-588)4144086-9 (DE-588)4143413-4 |
| title | Basement membranes |
| title_auth | Basement membranes |
| title_exact_search | Basement membranes |
| title_full | Basement membranes edited by Jeffrey H. Miner (Washington University , St. Louis, MO, USA) |
| title_fullStr | Basement membranes edited by Jeffrey H. Miner (Washington University , St. Louis, MO, USA) |
| title_full_unstemmed | Basement membranes edited by Jeffrey H. Miner (Washington University , St. Louis, MO, USA) |
| title_short | Basement membranes |
| title_sort | basement membranes |
| topic | Basalmembran (DE-588)4144086-9 gnd |
| topic_facet | Basalmembran Aufsatzsammlung |
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