Haematology:
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Oxford, United Kingdom
Oxford University Press
[2016]
|
| Ausgabe: | Second edition |
| Schriftenreihe: | Fundamentals of biomedical science
|
| Schlagworte: | |
| Online-Zugang: | Klappentext Inhaltsverzeichnis |
| Beschreibung: | XXIII, 661 Seiten Illustrationen, Diagramme |
| ISBN: | 9780199668861 0199668868 |
Internformat
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| 245 | 1 | 0 | |a Haematology |c Dr Gary W. Moore, BSc, DBMS, CSci, FIBMS, CBiol, MRSB, CertMHS, Gavin Knight, BSc (Hons), MSc, SFHEA, FIBMS, CSci, Dr Andrew D. Blann, PhD, FRCPath, FRCPE, FIBMS, CSci |
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Datensatz im Suchindex
| _version_ | 1804175721968435200 |
|---|---|
| adam_text | New to this edition:
Case studies have been extended to help foster an understanding of
the diagnostic process, taking the reader through each clinical case
from initial presentation to the interpretation of results.
A new chapter on acquired disorders of haemostasis describes their
causes, their diagnosis, and how they can affect routine coagulation
screening tests.
A new final chapter presents three integrated case studies that bring
together the diverse characteristics of haematology and demonstrate
how they help to define a diagnosis and support clinical management.
C01A/teiA/t£
An introduction to the Fundamentals 3.5 Specific lineage haemopoiesis 60
of Biomedical Science series ix 3.6 Bone marrow sampling and analysis 66
Contributors xiii
Table 1 : Reference Ranges XV
Abbreviations xvii 2 Peripheral Blood Cells
in Health and Disease 73
1 Haematology and 1 4 The red blood cell in health
Haemopoiesis and disease 75
1 Introduction to haematology 3 4.1 The development of the red blood cel):
1.1 What is haematology? 3 erythropoiesis 76
1.2 The role of the biomedical scientist in the 4.2 The red blood cell membrane 81
haematology laboratory 6 4.3 The cytoplasm of the red blood cell 89
1.3 The role of haematology in the provision 4.4 The death of the red cell 102
of healthcare 10 4.5 Red cell morphology 104
1.4 The role of the professional body 12 4.6 An introduction to diseases of the red cell 109
2 Major haematology parameters
and basic techniques 16 5 Anaemia 1: The bone marrow,
2.1 Obtaining a sample 17 micronutrients, and disease in
2.2 Anticoagulants 18 other organs 113
2.3 An introduction to major techniques 19 5.1 Introduction to anaemia 114
2.4 The blood film 30 5.2 Anaemia arisingfrom changes in
2.5 The full blood count 32 the bone marrow 117
2.6 Rheology 38 5.3 Insufficient iron 121
27 The report form 40 5.4 Iron overload 126
2.8 Haemostasis 40 5.5 The role of the laboratory in
2.9 Haematinics 46 iron-related pathology 130
2.10 The reference range 48 5.6 Anaemia arisingfrom lack of vitamins 134
5.7 Anaemia of chronic disease (ACD) 146
3 Haemopoiesis and the bone
marrow 52 6 Anaemia 2: Haemolysis 152
3.1 Overview of the cellular constituents 6.1 Introduction to haemolytic anaemia 152
of the blood 52 6.2 Immune-mediated and other extrinsic7
3.2 Ontogeny of haemopoiesis 53 causes of haemolytic anaemia 154
3.3 Bone marrow architecture and cellularity 54 6.3 Haemoglobinopathy 163
3.4 Models of differentiation, stem cells, 6.4 Membrane defects 184
and growth factors 55 6.5 Principal enzyme defects 188
VI
CONTENTS
7 Blood-borne parasites 193 10.4 Bone marrow assessment 314
10.5 Cytochemistry 321
7.1 Introduction 193
7 ? Malâriâ 194 10.6 Immunophenotyping 324
menai la 10.7 Cytogenetic analysis 332
7.3 Babesiosis 216
10.8 Molecular techniques 336
7.4 Trypanosomiasis 218
7.5 Leishmaniasis 221 11 An introduction to classification
7.6 Filariasis 222 systems: myeloid neoplasms 341
8 White blood cells in health 11.1 Why is classification important? 342
and disease 229 11.2 The main classification systems 342
8.1 Introduction 230 11.3 Myelodysplastic syndrome 359
11.4 Myelodysplastic/myeloproliferative diseases 365
8.2 Granulocytes 230
11.5 Myeloproliferative neoplasms 367
8.3 Monocytes 248
8.4 Lymphocytes 250 12 An introduction to classification
8.5 Plasma cells 263 systems: lymphoid neoplasms 377
12.1 The World Health Organization
3 Haematological (WHO) classification of tumours of
Malignancies 265 haematopoietic and lymphoid tissues 378
12.2 WHO classification of precursor
9 An introduction to lymphoid neoplasms 381
haematological malignancies 267 12.3 Mature B-cell neoplasms 386
12.4 Mature T-cell and NK-cell neoplasms 413
9.1 A background to haematological malignancies 268
12.5 Hodgkin lymphoma 416
9.2 Signal transduction 273
9.3 An introduction to the cell cycle 274
4 Haemostasis in
9.4 Apoptosis 278 Health and Disease 421
9.5 Cancer stem cells 279
9.6 Chromosomes and nomenclature 281
13 Normal haemostasis 423
9.7 An introduction to genetic mutation 283
9.8 Epigenetics 292 13.1 Introduction to haemostasis 423
9.9 Clonality 295 13.2 Primary haemostasis 424
9.10 Mechanisms of oncogenesis 299 13.3 Secondary haemostasis 435
9.11 Inheritance and leukaemia 300 13.4 Regulation of secondary haemostasis 447
9.12 Environmental causes of haematological 13.5 Fibrinolysis 453
malignancies 301
14 Bleeding disorders and their
10 The laboratory investigation of laboratory investigation 461
haematological malignancies 306
14.1 Bleeding disorders 461
10.1 Patient presentation 307 14.2 Laboratory investigation of a
10.2 The full blood count 309 suspected bleeding disorder 465
10.3 Blood film 312 14.3 Diagnosis of platelet disorders 490
CONTENTS
15 Thrombophilia 507 17.3 Current therapeutic anticoagulant
pharmaceuticals for arterial
15.1 Introduction 507 thrombosis 584
15.2 Deficiency of the natural 17.4 Laboratory monitoring of
anticoagulants 509 anticoagulant therapy 585
15.3 Gain-of-function mutations 515 17.5 Management of VKA
15.4 Other thrombophilias 518 anticoagulant therapy 603
15.5 Pitfalls of thrombophilia testing 519
15.6 Antiphospholipid antibodies 523 5 Case Studies 613
15.7 Thrombosis 540 18 Case studies in haematology 615
16 Acquired disorders 18.1 Case study 1 615
of haemostasis 545
18.2 Case study 2 619
16.1 Acquired bleeding disorders 545 18.3 Case study 3 622
16.2 Acquired thrombotic disorders 561 Glossary 627
17 Haemostasis and anticoagulation 568 References 646
Index 647
17.1 Reasons for anticoagulation therapy 568
17.2 Current therapeutic anticoagulant
pharmaceuticals for VTE 573
|
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| id | DE-604.BV043216723 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:20:48Z |
| institution | BVB |
| isbn | 9780199668861 0199668868 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028639741 |
| oclc_num | 945683290 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-578 |
| owner_facet | DE-355 DE-BY-UBR DE-578 |
| physical | XXIII, 661 Seiten Illustrationen, Diagramme |
| publishDate | 2016 |
| publishDateSearch | 2016 |
| publishDateSort | 2016 |
| publisher | Oxford University Press |
| record_format | marc |
| series2 | Fundamentals of biomedical science |
| spelling | Haematology Dr Gary W. Moore, BSc, DBMS, CSci, FIBMS, CBiol, MRSB, CertMHS, Gavin Knight, BSc (Hons), MSc, SFHEA, FIBMS, CSci, Dr Andrew D. Blann, PhD, FRCPath, FRCPE, FIBMS, CSci Second edition Oxford, United Kingdom Oxford University Press [2016] © 2016 XXIII, 661 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Fundamentals of biomedical science Hämatologie (DE-588)4022796-0 gnd rswk-swf Hämatologie (DE-588)4022796-0 s DE-604 Moore, Gary W. (DE-588)142335614 edt Knight, Gavin (DE-588)142335622 edt Blann, Andrew D. (DE-588)142335630 edt Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639741&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Klappentext Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639741&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Haematology Hämatologie (DE-588)4022796-0 gnd |
| subject_GND | (DE-588)4022796-0 |
| title | Haematology |
| title_auth | Haematology |
| title_exact_search | Haematology |
| title_full | Haematology Dr Gary W. Moore, BSc, DBMS, CSci, FIBMS, CBiol, MRSB, CertMHS, Gavin Knight, BSc (Hons), MSc, SFHEA, FIBMS, CSci, Dr Andrew D. Blann, PhD, FRCPath, FRCPE, FIBMS, CSci |
| title_fullStr | Haematology Dr Gary W. Moore, BSc, DBMS, CSci, FIBMS, CBiol, MRSB, CertMHS, Gavin Knight, BSc (Hons), MSc, SFHEA, FIBMS, CSci, Dr Andrew D. Blann, PhD, FRCPath, FRCPE, FIBMS, CSci |
| title_full_unstemmed | Haematology Dr Gary W. Moore, BSc, DBMS, CSci, FIBMS, CBiol, MRSB, CertMHS, Gavin Knight, BSc (Hons), MSc, SFHEA, FIBMS, CSci, Dr Andrew D. Blann, PhD, FRCPath, FRCPE, FIBMS, CSci |
| title_short | Haematology |
| title_sort | haematology |
| topic | Hämatologie (DE-588)4022796-0 gnd |
| topic_facet | Hämatologie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639741&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639741&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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