Annotating new genes: from in silico screening to experimental validation
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Oxford
Woodhead
2012
|
| Schriftenreihe: | Woodhead Publishing series in biomedicine
15 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Includes bibliographical references and index In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented. Focuses not only on screening but also on biological validationsProvides details of databases and software (web interface) products for biologists with minimal computation skillsOffers a step-by-step outline of the procedure involved |
| Beschreibung: | 1 Online-Ressource (xviii, 178 pages) |
| ISBN: | 1908818123 9781908818126 9781907568688 1907568689 |
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Datensatz im Suchindex
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| author | Uchida, Shizuka |
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| discipline | Biologie |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:20:46Z |
| institution | BVB |
| isbn | 1908818123 9781908818126 9781907568688 1907568689 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028639049 |
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| physical | 1 Online-Ressource (xviii, 178 pages) |
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| publishDate | 2012 |
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| series2 | Woodhead Publishing series in biomedicine |
| spelling | Uchida, Shizuka Verfasser aut Annotating new genes from in silico screening to experimental validation Shizuka Uchida Oxford Woodhead 2012 1 Online-Ressource (xviii, 178 pages) txt rdacontent c rdamedia cr rdacarrier Woodhead Publishing series in biomedicine 15 Includes bibliographical references and index In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented. Focuses not only on screening but also on biological validationsProvides details of databases and software (web interface) products for biologists with minimal computation skillsOffers a step-by-step outline of the procedure involved SCIENCE / Life Sciences / Biochemistry bisacsh Bioinformatics fast Genomics fast Bioinformatics Biometry Genetics Genomics http://www.sciencedirect.com/science/book/9781907568688 Verlag Volltext |
| spellingShingle | Uchida, Shizuka Annotating new genes from in silico screening to experimental validation SCIENCE / Life Sciences / Biochemistry bisacsh Bioinformatics fast Genomics fast Bioinformatics Biometry Genetics Genomics |
| title | Annotating new genes from in silico screening to experimental validation |
| title_auth | Annotating new genes from in silico screening to experimental validation |
| title_exact_search | Annotating new genes from in silico screening to experimental validation |
| title_full | Annotating new genes from in silico screening to experimental validation Shizuka Uchida |
| title_fullStr | Annotating new genes from in silico screening to experimental validation Shizuka Uchida |
| title_full_unstemmed | Annotating new genes from in silico screening to experimental validation Shizuka Uchida |
| title_short | Annotating new genes |
| title_sort | annotating new genes from in silico screening to experimental validation |
| title_sub | from in silico screening to experimental validation |
| topic | SCIENCE / Life Sciences / Biochemistry bisacsh Bioinformatics fast Genomics fast Bioinformatics Biometry Genetics Genomics |
| topic_facet | SCIENCE / Life Sciences / Biochemistry Bioinformatics Genomics Biometry Genetics |
| url | http://www.sciencedirect.com/science/book/9781907568688 |
| work_keys_str_mv | AT uchidashizuka annotatingnewgenesfrominsilicoscreeningtoexperimentalvalidation |