Proteases of infectious agents:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego, Calif.
Academic
©1999
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xvii, 282 pages, [15] pages of color plates) |
| ISBN: | 9780124205109 0124205100 9781429497749 1429497742 0080525741 9780080525747 1281025119 9781281025111 |
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| 245 | 1 | 0 | |a Proteases of infectious agents |c edited by Ben M. Dunn |
| 264 | 1 | |a San Diego, Calif. |b Academic |c ©1999 | |
| 300 | |a 1 Online-Ressource (xvii, 282 pages, [15] pages of color plates) | ||
| 336 | |b txt |2 rdacontent | ||
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| 500 | |a Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Protease Inhibitors / chemical synthesis | |
| 650 | 4 | |a Protease Inhibitors / therapeutic use | |
| 650 | 4 | |a Communicable Diseases / enzymology | |
| 650 | 4 | |a Communicable Diseases / therapy | |
| 650 | 4 | |a Communicable diseases | |
| 650 | 4 | |a Enzymes protéolytiques | |
| 650 | 4 | |a Antiprotéases | |
| 650 | 4 | |a Enzymes microbiennes | |
| 650 | 7 | |a SCIENCE / Life Sciences / Biochemistry |2 bisacsh | |
| 650 | 7 | |a Microbial enzymes |2 fast | |
| 650 | 7 | |a Protease inhibitors |2 fast | |
| 650 | 7 | |a Proteolytic enzymes |2 fast | |
| 650 | 4 | |a Proteolytic enzymes | |
| 650 | 4 | |a Protease inhibitors | |
| 650 | 4 | |a Microbial enzymes | |
| 700 | 1 | |a Dunn, Ben M. |e Sonstige |4 oth | |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/book/9780124205109 |x Verlag |3 Volltext |
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| ctrlnum | (OCoLC)162128877 (DE-599)BVBBV043215963 |
| dewey-full | 572/.76 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572/.76 |
| dewey-search | 572/.76 |
| dewey-sort | 3572 276 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
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| id | DE-604.BV043215963 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:20:46Z |
| institution | BVB |
| isbn | 9780124205109 0124205100 9781429497749 1429497742 0080525741 9780080525747 1281025119 9781281025111 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028638988 |
| oclc_num | 162128877 |
| open_access_boolean | |
| owner | DE-1046 |
| owner_facet | DE-1046 |
| physical | 1 Online-Ressource (xvii, 282 pages, [15] pages of color plates) |
| psigel | ZDB-33-ESD ZDB-33-EBS FLA_PDA_ESD |
| publishDate | 1999 |
| publishDateSearch | 1999 |
| publishDateSort | 1999 |
| publisher | Academic |
| record_format | marc |
| spelling | Proteases of infectious agents edited by Ben M. Dunn San Diego, Calif. Academic ©1999 1 Online-Ressource (xvii, 282 pages, [15] pages of color plates) txt rdacontent c rdamedia cr rdacarrier Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery Includes bibliographical references and index Protease Inhibitors / chemical synthesis Protease Inhibitors / therapeutic use Communicable Diseases / enzymology Communicable Diseases / therapy Communicable diseases Enzymes protéolytiques Antiprotéases Enzymes microbiennes SCIENCE / Life Sciences / Biochemistry bisacsh Microbial enzymes fast Protease inhibitors fast Proteolytic enzymes fast Proteolytic enzymes Protease inhibitors Microbial enzymes Dunn, Ben M. Sonstige oth http://www.sciencedirect.com/science/book/9780124205109 Verlag Volltext |
| spellingShingle | Proteases of infectious agents Protease Inhibitors / chemical synthesis Protease Inhibitors / therapeutic use Communicable Diseases / enzymology Communicable Diseases / therapy Communicable diseases Enzymes protéolytiques Antiprotéases Enzymes microbiennes SCIENCE / Life Sciences / Biochemistry bisacsh Microbial enzymes fast Protease inhibitors fast Proteolytic enzymes fast Proteolytic enzymes Protease inhibitors Microbial enzymes |
| title | Proteases of infectious agents |
| title_auth | Proteases of infectious agents |
| title_exact_search | Proteases of infectious agents |
| title_full | Proteases of infectious agents edited by Ben M. Dunn |
| title_fullStr | Proteases of infectious agents edited by Ben M. Dunn |
| title_full_unstemmed | Proteases of infectious agents edited by Ben M. Dunn |
| title_short | Proteases of infectious agents |
| title_sort | proteases of infectious agents |
| topic | Protease Inhibitors / chemical synthesis Protease Inhibitors / therapeutic use Communicable Diseases / enzymology Communicable Diseases / therapy Communicable diseases Enzymes protéolytiques Antiprotéases Enzymes microbiennes SCIENCE / Life Sciences / Biochemistry bisacsh Microbial enzymes fast Protease inhibitors fast Proteolytic enzymes fast Proteolytic enzymes Protease inhibitors Microbial enzymes |
| topic_facet | Protease Inhibitors / chemical synthesis Protease Inhibitors / therapeutic use Communicable Diseases / enzymology Communicable Diseases / therapy Communicable diseases Enzymes protéolytiques Antiprotéases Enzymes microbiennes SCIENCE / Life Sciences / Biochemistry Microbial enzymes Protease inhibitors Proteolytic enzymes |
| url | http://www.sciencedirect.com/science/book/9780124205109 |
| work_keys_str_mv | AT dunnbenm proteasesofinfectiousagents |