Bioactive lipid mediators: current reviews and protocols
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Tokyo
Springer
[2015]
|
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online Ressource (ix, 426 Seiten) Illustrationen |
| ISBN: | 9784431556695 |
| DOI: | 10.1007/978-4-431-55669-5 |
Internformat
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| 245 | 1 | 0 | |a Bioactive lipid mediators |b current reviews and protocols |c Takehiko Yokomizo, Makoto Murakami, editors |
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| 650 | 4 | |a Life Sciences | |
| 650 | 4 | |a Lipidology | |
| 650 | 4 | |a Cell Biology | |
| 650 | 4 | |a Human Physiology | |
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| 700 | 1 | |a Yokomizo, Takehiko |4 edt | |
| 700 | 1 | |a Murakami, Makoto |4 edt | |
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Datensatz im Suchindex
| _version_ | 1804175706917175296 |
|---|---|
| adam_text | BIOACTIVE LIPID MEDIATORS
/
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PART I ENZYMES AND RECEPTORS FOR LIPID MEDIATORS
1 LYSOPHOSPHOLIPID ACYLTRANSFERASES
2 PHOSPHOLIPASE A2
3 PROSTAGLANDIN TERMINAL SYNTHASES AS NOVEL DRUG TARGETS
4 PATHOPHYSIOLOGICAL ROLES OF PROSTANOID RECEPTORS IN THE CENTRAL
NERVOUS SYSTEM
5 LIPOXYGENASES: A CHRONOLOGICAL PERSPECTIVE ON THE SYNTHESIS OF S AND R
FATTY ACID HYDROPEROXIDES
6 LEUKOTRIENE B4 RECEPTORS
7 PLATELET-ACTIVATING FACTOR (PAF) IN INFECTIOUS DISEASES
8 LYSOPHOSPHOLIPID MEDIATORS: THEIR RECEPTORS AND SYNTHETIC PATHWAYS
9 SPHINGOLIPID METABOLISM VIA SPHINGOSINE 1-PHOSPHATE AND ITS ROLE IN
PHYSIOLOGY, PATHOLOGY, AND NUTRITION
10 FATTY ACIDS RECEPTORS
11 OMEGA-3 FATTY ACID METABOLISM AND REGULATION OF INFLAMMATION
PART II LIPID MEDIATORS IN DROSOPHILA AND ZEBRAFISH
12 MEMBRANE LIPID TRANSPORTERS IN DROSOPHILA MELANOGASTER
13 DROSOPHILA: A MODEL FOR STUDYING PROSTAGLANDIN SIGNALING
14 ZEBRAFISH AS A MODEL ANIMAL FOR STUDYING LYSOPHOSPHATIDIC ACID
SIGNALING
15 SPHINGOSINE 1-PHOSPHATE SIGNALING VIA TRANSPORTERS IN ZEBRAFISH AND
MICE
PART III LIPID MEDIATORS AND DISEASES
16 LIPID MEDIATOR LPA-INDUCED DEMYELINATION AND SELF-AMPLIFICATION OF
LPA BIOSYNTHESIS IN CHRONIC PAIN MEMORY MECHANISMS
17 VASCULAR ENDOTHELIAL S1P2 RECEPTOR LIMITS TUMOR ANGIOGENESIS AND
HYPERPERMEABILITY
18 ROLES OF PROSTAGLANDINS IN REGULATION OF PATHOLOGICAL ANGIOGENESIS
AND LYMPHANGIOGENESIS
19 EICOSANOIDS AND AORTIC ANEURYSM
20 CYSTEINYL LEUKOTRIENES AND DISEASE
21 LIPID MEDIATORS AND SKIN DISEASES
22 ROLES AND ACTIONS OF ARACHIDONIC ACID-DERIVED BIOACTIVE LIPIDS IN
STRESS-RELATED BEHAVIORS
PART IV PROTOCOLS FOR ANALYZING LIPID MEDIATORS
23 BASIC TECHNIQUES FOR LIPID EXTRACTION FROM TISSUES AND CELLS
24 COMPREHENSIVE ANALYSIS OF EICOSANOIDS
25 MASS SPECTROMETRIC ANALYSIS OF PHOSPHOLIPIDS BY TARGET DISCOVERY
APPROACH
26 DETERMINATION OF SPHINGOLIPIDS BY LC-MS/MS
27 LIPID MACHINERY INVESTIGATION USING MALDI IMAGING MASS SPECTROMETRY.
28 MEASURING ACTIVATION OF LIPID G PROTEIN-COUPLED RECEPTORS USING THE
TGF-Α SHEDDING ASSAY
29 A NOVEL ANTI-FLAG MONOCLONAL ANTIBODY IS USEFUL TO STUDY GPCRS
INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
BIOACTIVE LIPID MEDIATORS
/
: 2015
ABSTRACT / INHALTSTEXT
THIS BOOK SUMMARIZES THE MOST RECENT PROGRESS IN THE STUDIES OF LIPID
MEDIATORS FROM THE MOLECULAR TO CLINICAL LEVEL AND INTRODUCES NEWLY
CREATED TOOLS FOR ANALYSIS INCLUDING IMAGING MASS SPECTROMETRY.
COMPRISING 29 CHAPTERS DIVIDED INTO FOUR MAJOR PARTS, THE BOOK DESCRIBES
THE MOLECULAR NATURES OF ENZYMES, TRANSPORTERS, AND RECEPTORS FOR LIPID
MEDIATORS (PART I), THE FUNCTION OF LIPID MEDIATORS IN DROSOPHILA AND
ZEBRAFISH (PART II), THE RELATIONSHIPS BETWEEN LIPID MEDIATORS AND
VARIOUS DISEASES (PART III), AND DETAILED PROCEDURES OF EXTRACTION,
PREPARATION, AND QUANTIFICATION OF LIPID MEDIATORS (PART IV). RESEARCH
ON LIPID MEDIATORS INITIALLY STARTED WITH ANALYSIS OF THE ACTION OF
ASPIRIN, AND SUBSEQUENT BIOCHEMICAL EXPERIMENTS IDENTIFIED MANY ENZYMES
AND RECEPTORS RESPONSIBLE FOR THE BIOSYNTHESIS AND SIGNAL TRANSDUCTION
OF INDIVIDUAL LIPID MEDIATORS. THROUGH THE PHENOTYPIC ANALYSES OF
TRANSGENIC AND KNOCKOUT MICE, IT HAS BEEN SHOWN THAT THE DYSREGULATION
OF SOME LIPID MEDIATORS CAUSES INFLAMMATORY, IMMUNE, OR ONCOGENIC
DISORDERS. LIPID MEDIATORS HAVE ATTRACTED INCREASED ATTENTION BECAUSE
THEIR STRUCTURES ARE CONSERVED AMONG DIFFERENT SPECIES, AND THEIR
BIOSYNTHETIC AND SIGNALING PATHWAYS HAVE BEEN DECIPHERED AT THE
MOLECULAR LEVEL. MANY DRUGS THAT TARGET LIPID MEDIATORS ARE ALREADY
BEING USED IN HOSPITALS, AND THIS BOOK SUGGESTS FURTHER POSSIBILITIES
FOR DEVELOPMENT OF A WIDE VARIETY OF SUCH DRUGS. VERY RECENTLY, HIGHLY
SENSITIVE MASS SPECTROMETRY HAS BEGUN TO BE USED TO IDENTIFY NOVEL LIPID
MEDIATORS THAT ARE PRESENT ONLY IN TRACE AMOUNTS IN TISSUES BUT WITH
ROBUST BIOLOGICAL ACTIVITY. WRITTEN BY INTERNATIONAL EXPERTS, THIS BOOK
PROVIDES READERS A COMPREHENSIVE VIEW OF LIPID MEDIATORS AND RELATED
TOPICS AND HELPS IN THE PROCESS OF DETERMINING RESEARCH TARGETS FOR THE
NEAR FUTURE
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| discipline | Biologie |
| doi_str_mv | 10.1007/978-4-431-55669-5 |
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| indexdate | 2024-07-10T07:20:33Z |
| institution | BVB |
| isbn | 9784431556695 |
| language | English |
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| spelling | Bioactive lipid mediators current reviews and protocols Takehiko Yokomizo, Makoto Murakami, editors Tokyo Springer [2015] 1 Online Ressource (ix, 426 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Life sciences Human physiology Lipids Cell biology Life Sciences Lipidology Cell Biology Human Physiology Biowissenschaften Yokomizo, Takehiko edt Murakami, Makoto edt Erscheint auch als Druck-Ausgabe, Hardcover 978-4-431-55668-8 Erscheint auch als Druck-Ausgabe, Paperback 978-4-431-56247-4 https://doi.org/10.1007/978-4-431-55669-5 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028632030&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028632030&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Bioactive lipid mediators current reviews and protocols Life sciences Human physiology Lipids Cell biology Life Sciences Lipidology Cell Biology Human Physiology Biowissenschaften |
| title | Bioactive lipid mediators current reviews and protocols |
| title_auth | Bioactive lipid mediators current reviews and protocols |
| title_exact_search | Bioactive lipid mediators current reviews and protocols |
| title_full | Bioactive lipid mediators current reviews and protocols Takehiko Yokomizo, Makoto Murakami, editors |
| title_fullStr | Bioactive lipid mediators current reviews and protocols Takehiko Yokomizo, Makoto Murakami, editors |
| title_full_unstemmed | Bioactive lipid mediators current reviews and protocols Takehiko Yokomizo, Makoto Murakami, editors |
| title_short | Bioactive lipid mediators |
| title_sort | bioactive lipid mediators current reviews and protocols |
| title_sub | current reviews and protocols |
| topic | Life sciences Human physiology Lipids Cell biology Life Sciences Lipidology Cell Biology Human Physiology Biowissenschaften |
| topic_facet | Life sciences Human physiology Lipids Cell biology Life Sciences Lipidology Cell Biology Human Physiology Biowissenschaften |
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