Protein Modifications in Pathogenic Dysregulation of Signaling:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Tokyo
Springer Japan
2015
|
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online Ressource (IX, 348 p. 86 illus., 46 illus. in color) |
| ISBN: | 9784431555612 |
| DOI: | 10.1007/978-4-431-55561-2 |
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| 245 | 1 | 0 | |a Protein Modifications in Pathogenic Dysregulation of Signaling |c Jun-ichiro Inoue, Mutsuhiro Takekawa, ed. |
| 264 | 1 | |a Tokyo |b Springer Japan |c 2015 | |
| 300 | |a 1 Online Ressource (IX, 348 p. 86 illus., 46 illus. in color) | ||
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| 650 | 4 | |a Cell biology | |
| 650 | 4 | |a Life Sciences | |
| 650 | 4 | |a Protein Science | |
| 650 | 4 | |a Cell Biology | |
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| 650 | 4 | |a Biowissenschaften | |
| 700 | 1 | |a Inoue, Jun-ichiro |e Sonstige |4 oth | |
| 700 | 1 | |a Takekawa, Mutsuhiro |e Sonstige |4 oth | |
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Datensatz im Suchindex
| _version_ | 1804175706820706304 |
|---|---|
| adam_text | PROTEIN MODIFICATIONS IN PATHOGENIC DYSREGULATION OF SIGNALING
/
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PREFACE
PART I NOVEL ANALYTICAL PROCEDURES FOR SIGNAL TRANSDUCTION
1 PHOSPHOPROTEOMICS-BASED NETWORK ANALYSIS OF CANCER CELL SIGNALING
SYSTEMS (HIROKO KOZUKA-HATA AND MASAAKI OYAMA)
2 PHOS-TAG-BASED AFFINITY CHROMATOGRAPHY TECHNIQUES FOR ENRICHMENT OF
THE PHOSPHOPROTEOME (EIJI KINOSHITA, EMIKO KINOSHITA-KIKUTA, AND TOHRU
KOIKE)
3 VISUALIZATION OF INTRACELLULAR SIGNALING WITH FLUORESCENCE RESONANCE
ENERGY TRANSFER-BASED BIOSENSORS (KAZUHIRO AOKI)
4 TECHNOLOGY OF WHEAT CELL-FREE BASED PROTEIN ARRAY FOR BIOCHEMICAL
ANALYSES OF PROTEIN KINASES AND UBIQUITIN E3 LIGASES (HIROTAKA
TAKAHASHI, KEIICHIROU NEMOTO, RAMADAN ABDELAZIZ, ATSUSHI UEMATSU, AND
TATSUYA SAWASAKI)
PART II MATHEMATICAL SIMULATION OF SIGNAL TRANSDUCTION
5 POTENTIAL ROLES OF SPATIAL PARAMETERS IN THE REGULATION OF NF-ΚB
OSCILLATIONS, AS REVEALED BY COMPUTER SIMULATIONS (DAISUKE OHSHIMA,
JUN-ICHIRO INOUE, AND KAZUHISA ICHIKAWA)
6 STOCHASTIC SIMULATION OF STRESS GRANULES (DAISUKE OHSHIMA, KYOKO
ARIMOTO-MATSUZAKI, TAICHIRO TOMIDA, MUTSUHIRO TAKEKAWA, AND KAZUHISA
ICHIKAWA)
7 TEMPORAL CODING OF INSULIN SIGNALING (HIROYUKI KUBOTA AND SHINYA
KURODA)
PART III STRUCTURAL ANALYSIS OF SIGNAL TRANSDUCTION
8 STRUCTURAL BIOLOGY OF PROTEIN POST-TRANSCRIPTIONAL MODIFICATIONS AND
CELLULAR SIGNALING (KAZUKI KATO, HIROSHI NISHIMASU, RYOHEI ISHII, OSAMU
NUREKI, AND RYUICHIRO ISHITANI)
9 STRUCTURAL BASIS FOR THE SIGNAL INITIATION BY TNF AND TNFR (TERUYA
NAKAMURA, YOHEI MUKAI, YASUO TSUTSUMI, AND YURIKO YAMAGATA)
10 REGULATION OF NF-ΚB PATHWAY BY LINKAGE-SPECIFIC UBIQUITIN-BINDING
DOMAINS (YUSUKE SATO)
PART IV REGULATION OF SIGNAL TRANSDUCTION BY POST-TRANSLATIONAL
MODIFICATIONS AND ITS PATHOGENIC DYSREGULATION
11 NF-ΚB SIGNALING AND LYMPHOID MALIGNANCIES (SHOJI YAMAOKA)
12 UBIQUITINATION-MEDIATED NF-ΚB REGULATION IN INFLAMMATORY RESPONSE
(FUMINORI TOKUNAGA)
13 NF-ΚB SIGNALING IN OSTEOCLASTOGENESIS (YUU TAGUCHI, JIN GOHDA, AND
JUN-ICHIRO INOUE)
14 MITOGEN-ACTIVATED PROTEIN KINASE SIGNALING AND CANCER (MUTSUHIRO
TAKEKAWA AND YUJI KUBOTA)
15 CRITICAL ROLES OF THE AKT SUBSTRATE GIRDIN IN DISEASE INITIATION AND
PROGRESSION (ATSUSHI ENOMOTO, LIANG WENG, AND MASAHIDE TAKAHASHI)
16 PROTEIN MODIFICATIONS PACE THE CIRCADIAN OSCILLATION OF BIOLOGICAL
CLOCKS (HIKARI YOSHITANE AND YOSHITAKA FUKADA)
17 KEAP1-NRF2 REGULATORY SYSTEM AND CANCER (KEIKO TAGUCHI AND MASAYUKI
YAMAMOTO)
18 ACTIN FILAMENT FORMATION IN MYOFIBRILS AND CELL PROTRUSIONS REGULATED
BY SIGNAL TRANSDUCTION (TAKESHI ENDO AND KAZUNORI TAKANO)
19 MOLECULAR SIGNALING AND ITS PATHOGENIC ALTERATIONS IN NEUROMUSCULAR
JUNCTION FORMATION AND MAINTENANCE (RYO UETA AND YUJI YAMANASHI)
20 POST-TRANSLATIONAL MODIFICATION OF TCF/LEF: NEW INSIGHTS INTO THE
REGULATION OF WNT/Β-CATENIN SIGNALING (TOHRU ISHITANI)
BM INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
PROTEIN MODIFICATIONS IN PATHOGENIC DYSREGULATION OF SIGNALING
/
: 2015
ABSTRACT / INHALTSTEXT
THIS BOOK IS DEVOTED TO RECENT ADVANCES IN ANALYSIS OF THE MOLECULAR
BASIS AND DYNAMICS OF POST-TRANSLATIONAL MODIFICATIONS (PTMS) OF
PROTEINS FOR A COMPREHENSIVE UNDERSTANDING OF THEIR KEY ROLES IN CELL
SIGNALING NETWORKS AND DIVERSE BIOLOGICAL PROCESSES, AND THEIR
PERTURBATION IN A VARIETY OF LIFE-THREATENING DISEASES SUCH AS CANCER
AND INFLAMMATORY DISEASES. THE BOOK INCLUDES RESEARCH REGARDING PTMS AND
METHODS OF THEIR INVESTIGATION DERIVED FROM INTERDISCIPLINARY
COLLABORATIONS BETWEEN LEADING SCIENTISTS IN THE FIELDS OF MOLECULAR,
MEDICAL, PROTEOMIC, STRUCTURAL, AND MATHEMATICAL BIOLOGY. THIS BOOK
CONSISTS OF FOUR SECTIONS. THE FIRST PART FOCUSES ON RECENT ADVANCES IN
PROCEDURES FOR ANALYSIS OF PTMS AND CELL SIGNALING. THE SECOND PART IS
DEVOTED TO MATHEMATICAL SIMULATION OF SIGNAL TRANSDUCTION PATHWAYS AND
OF THE FORMATION OF PROTEIN COMPLEXES IN LIVING CELLS. THE THIRD PART
DEALS WITH STRUCTURAL AND FUNCTIONAL ANALYSES OF PROTEINS INVOLVED IN
THE REGULATION OF PTMS AND CELL SIGNALING. THE FOURTH PART DESCRIBES
CUTTING-EDGE FINDINGS REGARDING CRITICAL SIGNAL TRANSDUCTION PATHWAYS
AND THEIR DYSREGULATION IN HUMAN DISEASES. THIS BOOK IS AIMED AT BOTH
ESTABLISHED SCIENTISTS AND STUDENTS IN VARIOUS FIELDS OF BIOLOGY
INCLUDING MOLECULAR, CELLULAR, STRUCTURAL, PROTEOMIC, AND MATHEMATICAL
BIOLOGY. READERS CAN ACCESS CUTTING-EDGE RESEARCH AND METHODOLOGIES IN
THEIR OWN FIELD AS WELL AS INTERDISCIPLINARY RESEARCH THAT IMPACTS ON
THEIR FIELD. THE BOOK CAN FUNCTION AS A REFERENCE FOR PHARMACEUTICAL
SCIENTISTS, BIOMEDICAL RESEARCHERS, AND CLINICIANS FOR THE DEVELOPMENT
OF MOLECULAR-TARGETED THERAPY OF HUMAN DISEASES
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| discipline | Biologie |
| doi_str_mv | 10.1007/978-4-431-55561-2 |
| format | Electronic eBook |
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| spelling | Protein Modifications in Pathogenic Dysregulation of Signaling Jun-ichiro Inoue, Mutsuhiro Takekawa, ed. Tokyo Springer Japan 2015 1 Online Ressource (IX, 348 p. 86 illus., 46 illus. in color) txt rdacontent c rdamedia cr rdacarrier Life sciences Cancer research Proteins Cell biology Life Sciences Protein Science Cell Biology Cancer Research Biowissenschaften Inoue, Jun-ichiro Sonstige oth Takekawa, Mutsuhiro Sonstige oth Erscheint auch als Druckausgabe 978-4-431-55560-5 https://doi.org/10.1007/978-4-431-55561-2 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028631986&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028631986&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Protein Modifications in Pathogenic Dysregulation of Signaling Life sciences Cancer research Proteins Cell biology Life Sciences Protein Science Cell Biology Cancer Research Biowissenschaften |
| title | Protein Modifications in Pathogenic Dysregulation of Signaling |
| title_auth | Protein Modifications in Pathogenic Dysregulation of Signaling |
| title_exact_search | Protein Modifications in Pathogenic Dysregulation of Signaling |
| title_full | Protein Modifications in Pathogenic Dysregulation of Signaling Jun-ichiro Inoue, Mutsuhiro Takekawa, ed. |
| title_fullStr | Protein Modifications in Pathogenic Dysregulation of Signaling Jun-ichiro Inoue, Mutsuhiro Takekawa, ed. |
| title_full_unstemmed | Protein Modifications in Pathogenic Dysregulation of Signaling Jun-ichiro Inoue, Mutsuhiro Takekawa, ed. |
| title_short | Protein Modifications in Pathogenic Dysregulation of Signaling |
| title_sort | protein modifications in pathogenic dysregulation of signaling |
| topic | Life sciences Cancer research Proteins Cell biology Life Sciences Protein Science Cell Biology Cancer Research Biowissenschaften |
| topic_facet | Life sciences Cancer research Proteins Cell biology Life Sciences Protein Science Cell Biology Cancer Research Biowissenschaften |
| url | https://doi.org/10.1007/978-4-431-55561-2 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028631986&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028631986&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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