GFP whole cell microbial biosensors: scale-up and scale-down effects on biopharmaceutical processes
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, N.Y.
ASME
2013
|
| Schriftenreihe: | Biomedical & nanomedical technologies
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Title from PDF t.p. (viewed on January 26, 2013) Includes bibliographical references (p. 36-43) 1. Interaction between fluid flow and microbial cells: importance of the operating scale -- 1.1 Different scales involved in the development of microbial bioprocesses -- 1.2 Hydrodynamic modeling of the substrate heterogeneites perceived by cells -- 2. Stochastic simulation of the displacement of microbial cells along concentration field -- 2.1 Microbial stress response: different timescales involved -- 3. Experimental results gained from the physiological response of GFP biosensors in scale-down conditions -- 3.1 General stress response in scale-down bioreactors: rpoS::GFP -- 3.2 Use of destabilized GFP variants -- 4. Another source of information: protein leakage and the study of the secretome -- References Two strategies are usually considered for the optimization of microbial bioprocesses. The first one involves genetic or metabolic engineering of the target microbial strains in order to improve its production efficiency or its tolerance to adverse conditions. The second one is based on the chemical engineering improvement of the bioreactors and scaling-up rules. This work is more particularly dedicated to this second class of parameters |
| Beschreibung: | 1 electronic text (43 p.) |
| ISBN: | 1606504177 1606504274 9781606504178 9781606504277 |
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| 246 | 1 | 3 | |a Green fluorescent protein whole cell microbial biosensors |
| 246 | 1 | 3 | |a Scale-up and scale-down effects on biopharmaceutical processes |
| 264 | 1 | |a New York, N.Y. |b ASME |c 2013 | |
| 300 | |a 1 electronic text (43 p.) | ||
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| 490 | 0 | |a Biomedical & nanomedical technologies | |
| 500 | |a Title from PDF t.p. (viewed on January 26, 2013) | ||
| 500 | |a Includes bibliographical references (p. 36-43) | ||
| 500 | |a 1. Interaction between fluid flow and microbial cells: importance of the operating scale -- 1.1 Different scales involved in the development of microbial bioprocesses -- 1.2 Hydrodynamic modeling of the substrate heterogeneites perceived by cells -- | ||
| 500 | |a 2. Stochastic simulation of the displacement of microbial cells along concentration field -- 2.1 Microbial stress response: different timescales involved -- | ||
| 500 | |a 3. Experimental results gained from the physiological response of GFP biosensors in scale-down conditions -- 3.1 General stress response in scale-down bioreactors: rpoS::GFP -- 3.2 Use of destabilized GFP variants -- | ||
| 500 | |a 4. Another source of information: protein leakage and the study of the secretome -- References | ||
| 500 | |a Two strategies are usually considered for the optimization of microbial bioprocesses. The first one involves genetic or metabolic engineering of the target microbial strains in order to improve its production efficiency or its tolerance to adverse conditions. The second one is based on the chemical engineering improvement of the bioreactors and scaling-up rules. This work is more particularly dedicated to this second class of parameters | ||
| 650 | 7 | |a MEDICAL / Microbiology |2 bisacsh | |
| 650 | 7 | |a Microbial biotechnology |2 local | |
| 650 | 7 | |a Green fluorescent protein |2 local | |
| 650 | 7 | |a Biosensors |2 local | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Microbial biotechnology | |
| 650 | 4 | |a Green fluorescent protein | |
| 650 | 4 | |a Biosensors | |
| 700 | 1 | |a Delvigne, Frank |e Sonstige |4 oth | |
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| dewey-full | 660.62 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 660 - Chemical engineering |
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| dewey-search | 660.62 |
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| discipline | Chemie / Pharmazie |
| format | Electronic eBook |
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| id | DE-604.BV043152491 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:19:05Z |
| institution | BVB |
| isbn | 1606504177 1606504274 9781606504178 9781606504277 |
| language | English |
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| spelling | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes Frank Delvigne ... [et al.] Green fluorescent protein whole cell microbial biosensors Scale-up and scale-down effects on biopharmaceutical processes New York, N.Y. ASME 2013 1 electronic text (43 p.) txt rdacontent c rdamedia cr rdacarrier Biomedical & nanomedical technologies Title from PDF t.p. (viewed on January 26, 2013) Includes bibliographical references (p. 36-43) 1. Interaction between fluid flow and microbial cells: importance of the operating scale -- 1.1 Different scales involved in the development of microbial bioprocesses -- 1.2 Hydrodynamic modeling of the substrate heterogeneites perceived by cells -- 2. Stochastic simulation of the displacement of microbial cells along concentration field -- 2.1 Microbial stress response: different timescales involved -- 3. Experimental results gained from the physiological response of GFP biosensors in scale-down conditions -- 3.1 General stress response in scale-down bioreactors: rpoS::GFP -- 3.2 Use of destabilized GFP variants -- 4. Another source of information: protein leakage and the study of the secretome -- References Two strategies are usually considered for the optimization of microbial bioprocesses. The first one involves genetic or metabolic engineering of the target microbial strains in order to improve its production efficiency or its tolerance to adverse conditions. The second one is based on the chemical engineering improvement of the bioreactors and scaling-up rules. This work is more particularly dedicated to this second class of parameters MEDICAL / Microbiology bisacsh Microbial biotechnology local Green fluorescent protein local Biosensors local Medizin Microbial biotechnology Green fluorescent protein Biosensors Delvigne, Frank Sonstige oth Erscheint auch als Druckausgabe 978-1-60650-427-7 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=522004 Aggregator Volltext |
| spellingShingle | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes MEDICAL / Microbiology bisacsh Microbial biotechnology local Green fluorescent protein local Biosensors local Medizin Microbial biotechnology Green fluorescent protein Biosensors |
| title | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes |
| title_alt | Green fluorescent protein whole cell microbial biosensors Scale-up and scale-down effects on biopharmaceutical processes |
| title_auth | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes |
| title_exact_search | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes |
| title_full | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes Frank Delvigne ... [et al.] |
| title_fullStr | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes Frank Delvigne ... [et al.] |
| title_full_unstemmed | GFP whole cell microbial biosensors scale-up and scale-down effects on biopharmaceutical processes Frank Delvigne ... [et al.] |
| title_short | GFP whole cell microbial biosensors |
| title_sort | gfp whole cell microbial biosensors scale up and scale down effects on biopharmaceutical processes |
| title_sub | scale-up and scale-down effects on biopharmaceutical processes |
| topic | MEDICAL / Microbiology bisacsh Microbial biotechnology local Green fluorescent protein local Biosensors local Medizin Microbial biotechnology Green fluorescent protein Biosensors |
| topic_facet | MEDICAL / Microbiology Microbial biotechnology Green fluorescent protein Biosensors Medizin |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=522004 |
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