Defining the mandate of proteomics in the post-genomics era: workshop report
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Washington, D.C.
National Academies Press
c2002
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references Research in proteomics is the next logical step after genomics in understanding life processes at the molecular level. In the largest sense proteomics encompasses knowledge of the structure, function and expression of all proteins in the biochemical or biological contexts of all organisms. Since that is an impossible goal to achieve, at least in our lifetimes, it is appropriate to set more realistic, achievable goals for the field. Up to now, primarily for reasons of feasibility, scientists have tended to concentrate on accumulating information about the nature of proteins and their absolute and relative levels of expression in cells (the primary tools for this have been 2D gel electrophoresis and mass spectrometry). Although these data have been useful and will continue to be so, the information inherent in the broader definition of proteomics must also be obtained if the true promise of the growing field is to be realized. Acquiring this knowledge is the challenge for researchers in proteomics and the means to support these endeavors need to be provided. An attempt has been made to present the major issues confronting the field of proteomics and two clear messages come through in this report. The first is that the mandate of proteomics is and should be much broader than is frequently recognized. The second is that proteomics is much more complicated than sequencing genomes. This will require new technologies but it is highly likely that many of these will be developed. Looking back 10 to 20 years from now, the question is: Will we have done the job wisely or wastefully? |
| Beschreibung: | 1 Online-Ressource (1 PDF file (1 v. (various pagings)) |
| ISBN: | 0309529069 9780309529068 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV043144027 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 151126s2002 |||| o||u| ||||||eng d | ||
| 020 | |a 0309529069 |c electronic bk. |9 0-309-52906-9 | ||
| 020 | |a 9780309529068 |c electronic bk. |9 978-0-309-52906-8 | ||
| 035 | |a (OCoLC)614937784 | ||
| 035 | |a (DE-599)BVBBV043144027 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-1046 |a DE-1047 | ||
| 082 | 0 | |a 572.6 |2 22 | |
| 245 | 1 | 0 | |a Defining the mandate of proteomics in the post-genomics era |b workshop report |c Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era ; U.S. National Committee for the International Union of Biochemistry and Molecular Biology, Board on International Scientific Organizations, Policy and Global Affairs Division, and Board on Life Sciences, Division of Earth and Life Studies, National Research Council of the National Academies |
| 264 | 1 | |a Washington, D.C. |b National Academies Press |c c2002 | |
| 300 | |a 1 Online-Ressource (1 PDF file (1 v. (various pagings)) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Includes bibliographical references | ||
| 500 | |a Research in proteomics is the next logical step after genomics in understanding life processes at the molecular level. In the largest sense proteomics encompasses knowledge of the structure, function and expression of all proteins in the biochemical or biological contexts of all organisms. Since that is an impossible goal to achieve, at least in our lifetimes, it is appropriate to set more realistic, achievable goals for the field. Up to now, primarily for reasons of feasibility, scientists have tended to concentrate on accumulating information about the nature of proteins and their absolute and relative levels of expression in cells (the primary tools for this have been 2D gel electrophoresis and mass spectrometry). Although these data have been useful and will continue to be so, the information inherent in the broader definition of proteomics must also be obtained if the true promise of the growing field is to be realized. Acquiring this knowledge is the challenge for researchers in proteomics and the means to support these endeavors need to be provided. An attempt has been made to present the major issues confronting the field of proteomics and two clear messages come through in this report. The first is that the mandate of proteomics is and should be much broader than is frequently recognized. The second is that proteomics is much more complicated than sequencing genomes. This will require new technologies but it is highly likely that many of these will be developed. Looking back 10 to 20 years from now, the question is: Will we have done the job wisely or wastefully? | ||
| 650 | 4 | |a Proteomics / United States / Congresses | |
| 650 | 4 | |a Genomics / United States / Congresses | |
| 650 | 4 | |a Proteins / United States / Congresses | |
| 650 | 4 | |a Proteomics | |
| 650 | 4 | |a Genomics | |
| 650 | 4 | |a Proteins | |
| 650 | 7 | |a SCIENCE / Life Sciences / Biochemistry |2 bisacsh | |
| 650 | 7 | |a Genomics |2 fast | |
| 650 | 7 | |a Proteins |2 fast | |
| 650 | 7 | |a Proteomics |2 fast | |
| 650 | 4 | |a Proteomics |v Congresses | |
| 650 | 4 | |a Genomics |v Congresses | |
| 650 | 4 | |a Proteins |v Congresses | |
| 651 | 4 | |a USA | |
| 655 | 7 | |0 (DE-588)1071861417 |a Konferenzschrift |2 gnd-content | |
| 710 | 2 | |a National Research Council (U.S.) |b Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era |e Sonstige |4 oth | |
| 710 | 2 | |a National Research Council (U.S.) |b Board on Life Sciences |e Sonstige |4 oth | |
| 710 | 2 | |a U.S. National Committee for the International Union of Biochemistry and Molecular Biology |e Sonstige |4 oth | |
| 856 | 4 | 0 | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238 |x Aggregator |3 Volltext |
| 912 | |a ZDB-4-EBA | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-028568218 | ||
| 966 | e | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238 |l FAW01 |p ZDB-4-EBA |q FAW_PDA_EBA |x Aggregator |3 Volltext | |
| 966 | e | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238 |l FAW02 |p ZDB-4-EBA |q FAW_PDA_EBA |x Aggregator |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804175596315475968 |
|---|---|
| any_adam_object | |
| building | Verbundindex |
| bvnumber | BV043144027 |
| collection | ZDB-4-EBA |
| ctrlnum | (OCoLC)614937784 (DE-599)BVBBV043144027 |
| dewey-full | 572.6 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.6 |
| dewey-search | 572.6 |
| dewey-sort | 3572.6 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>04331nmm a2200553zc 4500</leader><controlfield tag="001">BV043144027</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">151126s2002 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0309529069</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">0-309-52906-9</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780309529068</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">978-0-309-52906-8</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)614937784</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043144027</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-1046</subfield><subfield code="a">DE-1047</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572.6</subfield><subfield code="2">22</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Defining the mandate of proteomics in the post-genomics era</subfield><subfield code="b">workshop report</subfield><subfield code="c">Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era ; U.S. National Committee for the International Union of Biochemistry and Molecular Biology, Board on International Scientific Organizations, Policy and Global Affairs Division, and Board on Life Sciences, Division of Earth and Life Studies, National Research Council of the National Academies</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Washington, D.C.</subfield><subfield code="b">National Academies Press</subfield><subfield code="c">c2002</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (1 PDF file (1 v. (various pagings))</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Research in proteomics is the next logical step after genomics in understanding life processes at the molecular level. In the largest sense proteomics encompasses knowledge of the structure, function and expression of all proteins in the biochemical or biological contexts of all organisms. Since that is an impossible goal to achieve, at least in our lifetimes, it is appropriate to set more realistic, achievable goals for the field. Up to now, primarily for reasons of feasibility, scientists have tended to concentrate on accumulating information about the nature of proteins and their absolute and relative levels of expression in cells (the primary tools for this have been 2D gel electrophoresis and mass spectrometry). Although these data have been useful and will continue to be so, the information inherent in the broader definition of proteomics must also be obtained if the true promise of the growing field is to be realized. Acquiring this knowledge is the challenge for researchers in proteomics and the means to support these endeavors need to be provided. An attempt has been made to present the major issues confronting the field of proteomics and two clear messages come through in this report. The first is that the mandate of proteomics is and should be much broader than is frequently recognized. The second is that proteomics is much more complicated than sequencing genomes. This will require new technologies but it is highly likely that many of these will be developed. Looking back 10 to 20 years from now, the question is: Will we have done the job wisely or wastefully?</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteomics / United States / Congresses</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genomics / United States / Congresses</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteins / United States / Congresses</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteomics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genomics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteins</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">SCIENCE / Life Sciences / Biochemistry</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Genomics</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Proteins</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Proteomics</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteomics</subfield><subfield code="v">Congresses</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genomics</subfield><subfield code="v">Congresses</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteins</subfield><subfield code="v">Congresses</subfield></datafield><datafield tag="651" ind1=" " ind2="4"><subfield code="a">USA</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)1071861417</subfield><subfield code="a">Konferenzschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="710" ind1="2" ind2=" "><subfield code="a">National Research Council (U.S.)</subfield><subfield code="b">Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="710" ind1="2" ind2=" "><subfield code="a">National Research Council (U.S.)</subfield><subfield code="b">Board on Life Sciences</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="710" ind1="2" ind2=" "><subfield code="a">U.S. National Committee for the International Union of Biochemistry and Molecular Biology</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-4-EBA</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-028568218</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238</subfield><subfield code="l">FAW01</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FAW_PDA_EBA</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238</subfield><subfield code="l">FAW02</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FAW_PDA_EBA</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| genre | (DE-588)1071861417 Konferenzschrift gnd-content |
| genre_facet | Konferenzschrift |
| geographic | USA |
| geographic_facet | USA |
| id | DE-604.BV043144027 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:18:48Z |
| institution | BVB |
| isbn | 0309529069 9780309529068 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028568218 |
| oclc_num | 614937784 |
| open_access_boolean | |
| owner | DE-1046 DE-1047 |
| owner_facet | DE-1046 DE-1047 |
| physical | 1 Online-Ressource (1 PDF file (1 v. (various pagings)) |
| psigel | ZDB-4-EBA ZDB-4-EBA FAW_PDA_EBA |
| publishDate | 2002 |
| publishDateSearch | 2002 |
| publishDateSort | 2002 |
| publisher | National Academies Press |
| record_format | marc |
| spelling | Defining the mandate of proteomics in the post-genomics era workshop report Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era ; U.S. National Committee for the International Union of Biochemistry and Molecular Biology, Board on International Scientific Organizations, Policy and Global Affairs Division, and Board on Life Sciences, Division of Earth and Life Studies, National Research Council of the National Academies Washington, D.C. National Academies Press c2002 1 Online-Ressource (1 PDF file (1 v. (various pagings)) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references Research in proteomics is the next logical step after genomics in understanding life processes at the molecular level. In the largest sense proteomics encompasses knowledge of the structure, function and expression of all proteins in the biochemical or biological contexts of all organisms. Since that is an impossible goal to achieve, at least in our lifetimes, it is appropriate to set more realistic, achievable goals for the field. Up to now, primarily for reasons of feasibility, scientists have tended to concentrate on accumulating information about the nature of proteins and their absolute and relative levels of expression in cells (the primary tools for this have been 2D gel electrophoresis and mass spectrometry). Although these data have been useful and will continue to be so, the information inherent in the broader definition of proteomics must also be obtained if the true promise of the growing field is to be realized. Acquiring this knowledge is the challenge for researchers in proteomics and the means to support these endeavors need to be provided. An attempt has been made to present the major issues confronting the field of proteomics and two clear messages come through in this report. The first is that the mandate of proteomics is and should be much broader than is frequently recognized. The second is that proteomics is much more complicated than sequencing genomes. This will require new technologies but it is highly likely that many of these will be developed. Looking back 10 to 20 years from now, the question is: Will we have done the job wisely or wastefully? Proteomics / United States / Congresses Genomics / United States / Congresses Proteins / United States / Congresses Proteomics Genomics Proteins SCIENCE / Life Sciences / Biochemistry bisacsh Genomics fast Proteins fast Proteomics fast Proteomics Congresses Genomics Congresses Proteins Congresses USA (DE-588)1071861417 Konferenzschrift gnd-content National Research Council (U.S.) Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era Sonstige oth National Research Council (U.S.) Board on Life Sciences Sonstige oth U.S. National Committee for the International Union of Biochemistry and Molecular Biology Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238 Aggregator Volltext |
| spellingShingle | Defining the mandate of proteomics in the post-genomics era workshop report Proteomics / United States / Congresses Genomics / United States / Congresses Proteins / United States / Congresses Proteomics Genomics Proteins SCIENCE / Life Sciences / Biochemistry bisacsh Genomics fast Proteins fast Proteomics fast Proteomics Congresses Genomics Congresses Proteins Congresses |
| subject_GND | (DE-588)1071861417 |
| title | Defining the mandate of proteomics in the post-genomics era workshop report |
| title_auth | Defining the mandate of proteomics in the post-genomics era workshop report |
| title_exact_search | Defining the mandate of proteomics in the post-genomics era workshop report |
| title_full | Defining the mandate of proteomics in the post-genomics era workshop report Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era ; U.S. National Committee for the International Union of Biochemistry and Molecular Biology, Board on International Scientific Organizations, Policy and Global Affairs Division, and Board on Life Sciences, Division of Earth and Life Studies, National Research Council of the National Academies |
| title_fullStr | Defining the mandate of proteomics in the post-genomics era workshop report Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era ; U.S. National Committee for the International Union of Biochemistry and Molecular Biology, Board on International Scientific Organizations, Policy and Global Affairs Division, and Board on Life Sciences, Division of Earth and Life Studies, National Research Council of the National Academies |
| title_full_unstemmed | Defining the mandate of proteomics in the post-genomics era workshop report Steering Committee for Defining the Mandate of Proteomics in the Post-Genomics Era ; U.S. National Committee for the International Union of Biochemistry and Molecular Biology, Board on International Scientific Organizations, Policy and Global Affairs Division, and Board on Life Sciences, Division of Earth and Life Studies, National Research Council of the National Academies |
| title_short | Defining the mandate of proteomics in the post-genomics era |
| title_sort | defining the mandate of proteomics in the post genomics era workshop report |
| title_sub | workshop report |
| topic | Proteomics / United States / Congresses Genomics / United States / Congresses Proteins / United States / Congresses Proteomics Genomics Proteins SCIENCE / Life Sciences / Biochemistry bisacsh Genomics fast Proteins fast Proteomics fast Proteomics Congresses Genomics Congresses Proteins Congresses |
| topic_facet | Proteomics / United States / Congresses Genomics / United States / Congresses Proteins / United States / Congresses Proteomics Genomics Proteins SCIENCE / Life Sciences / Biochemistry Proteomics Congresses Genomics Congresses Proteins Congresses USA Konferenzschrift |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=87238 |
| work_keys_str_mv | AT nationalresearchcouncilussteeringcommitteefordefiningthemandateofproteomicsinthepostgenomicsera definingthemandateofproteomicsinthepostgenomicseraworkshopreport AT nationalresearchcouncilusboardonlifesciences definingthemandateofproteomicsinthepostgenomicseraworkshopreport AT usnationalcommitteefortheinternationalunionofbiochemistryandmolecularbiology definingthemandateofproteomicsinthepostgenomicseraworkshopreport |