Nuclear receptors: a practical approach
Gespeichert in:
Format: | Elektronisch E-Book |
---|---|
Sprache: | English |
Veröffentlicht: |
New York
Oxford University Press
1999
|
Schriftenreihe: | Practical approach series
207 |
Schlagworte: | |
Online-Zugang: | FAW01 FAW02 Volltext |
Beschreibung: | Includes bibliographical references and index The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clinical researchers. The first two chapters describe the evolutionary biology of the superfamily and explain how to clone and characterize new receptors. Chapter 3 shows how to identify the ligands of novel receptors and chapter 4 explains the kinetic analysis of receptor interactions. In chapter 5, the reader is guided through the functional characterization of coactivators using microinjection. The next section covers receptor phosphorylation, ligand regulated transcription, and hormone resistance syndromes. Chapter 9 describes the in vitro assembly of Hsp90 complexes and chapter 10 explains yeast as a model system for looking at receptor function. The final chapter shows how heterologous proteins can be regulated by fusion to the hormone binding domain of a receptor. Nuclear Receptors: A Practical Approach is a comprehensive guide to studying members of the superfamily and will be invaluable to all researchers old and new |
Beschreibung: | 1 Online-Ressource (xviii, 285 pages) |
ISBN: | 0585483728 1280375698 9780585483726 9781280375699 |
Internformat
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500 | |a The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clinical researchers. The first two chapters describe the evolutionary biology of the superfamily and explain how to clone and characterize new receptors. Chapter 3 shows how to identify the ligands of novel receptors and chapter 4 explains the kinetic analysis of receptor interactions. In chapter 5, the reader is guided through the functional characterization of coactivators using microinjection. The next section covers receptor phosphorylation, ligand regulated transcription, and hormone resistance syndromes. Chapter 9 describes the in vitro assembly of Hsp90 complexes and chapter 10 explains yeast as a model system for looking at receptor function. The final chapter shows how heterologous proteins can be regulated by fusion to the hormone binding domain of a receptor. Nuclear Receptors: A Practical Approach is a comprehensive guide to studying members of the superfamily and will be invaluable to all researchers old and new | ||
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dewey-search | 573.4/48845 |
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illustrated | Not Illustrated |
indexdate | 2024-07-10T07:18:37Z |
institution | BVB |
isbn | 0585483728 1280375698 9780585483726 9781280375699 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028562316 |
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physical | 1 Online-Ressource (xviii, 285 pages) |
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series2 | Practical approach series |
spelling | Nuclear receptors a practical approach edited by Didier Picard New York Oxford University Press 1999 1 Online-Ressource (xviii, 285 pages) txt rdacontent c rdamedia cr rdacarrier Practical approach series 207 Includes bibliographical references and index The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clinical researchers. The first two chapters describe the evolutionary biology of the superfamily and explain how to clone and characterize new receptors. Chapter 3 shows how to identify the ligands of novel receptors and chapter 4 explains the kinetic analysis of receptor interactions. In chapter 5, the reader is guided through the functional characterization of coactivators using microinjection. The next section covers receptor phosphorylation, ligand regulated transcription, and hormone resistance syndromes. Chapter 9 describes the in vitro assembly of Hsp90 complexes and chapter 10 explains yeast as a model system for looking at receptor function. The final chapter shows how heterologous proteins can be regulated by fusion to the hormone binding domain of a receptor. Nuclear Receptors: A Practical Approach is a comprehensive guide to studying members of the superfamily and will be invaluable to all researchers old and new Receptors, Cytoplasmic and Nuclear / laboratory manuals Transcription Factors / laboratory manuals Receptors, Steroid / laboratory manuals SOCIAL SCIENCE / Anthropology / Physical bisacsh Nuclear receptors (Biochemistry) fast Steroid hormones / Receptors fast Transcription factors fast Biochimie ram Hormones stéroides / Récepteurs ram Facteurs de transcription ram Steroid hormones / Receptors cct Nuclear receptors (Biochemistry) cct Transcription factors cct Receptors, Cytoplasmic and Nuclear cct Receptors, Steroid cct Steroid hormones Receptors Nuclear receptors (Biochemistry) Transcription factors Picard, Didier Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=98496 Aggregator Volltext |
spellingShingle | Nuclear receptors a practical approach Receptors, Cytoplasmic and Nuclear / laboratory manuals Transcription Factors / laboratory manuals Receptors, Steroid / laboratory manuals SOCIAL SCIENCE / Anthropology / Physical bisacsh Nuclear receptors (Biochemistry) fast Steroid hormones / Receptors fast Transcription factors fast Biochimie ram Hormones stéroides / Récepteurs ram Facteurs de transcription ram Steroid hormones / Receptors cct Nuclear receptors (Biochemistry) cct Transcription factors cct Receptors, Cytoplasmic and Nuclear cct Receptors, Steroid cct Steroid hormones Receptors Nuclear receptors (Biochemistry) Transcription factors |
title | Nuclear receptors a practical approach |
title_auth | Nuclear receptors a practical approach |
title_exact_search | Nuclear receptors a practical approach |
title_full | Nuclear receptors a practical approach edited by Didier Picard |
title_fullStr | Nuclear receptors a practical approach edited by Didier Picard |
title_full_unstemmed | Nuclear receptors a practical approach edited by Didier Picard |
title_short | Nuclear receptors |
title_sort | nuclear receptors a practical approach |
title_sub | a practical approach |
topic | Receptors, Cytoplasmic and Nuclear / laboratory manuals Transcription Factors / laboratory manuals Receptors, Steroid / laboratory manuals SOCIAL SCIENCE / Anthropology / Physical bisacsh Nuclear receptors (Biochemistry) fast Steroid hormones / Receptors fast Transcription factors fast Biochimie ram Hormones stéroides / Récepteurs ram Facteurs de transcription ram Steroid hormones / Receptors cct Nuclear receptors (Biochemistry) cct Transcription factors cct Receptors, Cytoplasmic and Nuclear cct Receptors, Steroid cct Steroid hormones Receptors Nuclear receptors (Biochemistry) Transcription factors |
topic_facet | Receptors, Cytoplasmic and Nuclear / laboratory manuals Transcription Factors / laboratory manuals Receptors, Steroid / laboratory manuals SOCIAL SCIENCE / Anthropology / Physical Nuclear receptors (Biochemistry) Steroid hormones / Receptors Transcription factors Biochimie Hormones stéroides / Récepteurs Facteurs de transcription Receptors, Cytoplasmic and Nuclear Receptors, Steroid Steroid hormones Receptors |
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work_keys_str_mv | AT picarddidier nuclearreceptorsapracticalapproach |