Protein-protein complexes: analysis, modeling and drug design
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| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
London
Imperial College Press
©2010
|
| Subjects: | |
| Online Access: | FAW01 FAW02 Volltext |
| Item Description: | Includes bibliographical references and index X-ray study of protein-protein complexes and analysis of interfaces / Joel Janin -- A structural perspective on protein-protein interactions in macromolecular assemblies / Ranjit P. Bahadur -- Energetics of protein-protein interactions / Ilian Jelesarov -- Kinetics of biomacromolecular complex formation: theory and experiment / Georgi V. Pachov, Razif R. Gabdoulline and Rebecca C. Wade -- Evolutionary trace of protein functional determinants / Olivier Lichtarge -- Protein-protein docking / Adrien Saladin and Chantal Prevost -- Data-driven docking: using external information to spark the biomolecular rendez-vous / Adrien S.J. Melquiond and Alexandre M.J.J. Bonvin -- High-resolution protein-protein docking / Nir London and Ora Schueler-Furman -- Scoring and refinement of predicted protein-protein complexes / Martin Zacharias -- Motif-mediated protein interactions and their role in disease / Holger Dinkel and Heinrich Sticht -- Prediction and calculation of protein-protein binding affinities and mutation effects / Sébastien Fiorucci, Serge Antonczak and Jérôme Golebiowski -- Small-molecule inhibitors of protein-protein interactions / Thorsten Berg -- Protein dynamics and drug design: the role of molecular simulations / Giulia Morra, Alessandro Genoni and Giorgio Colombo Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge |
| Physical Description: | 1 Online-Ressource (ix, 390 pages) |
| ISBN: | 184816338X 1848163398 1848163401 9781848163386 9781848163393 9781848163409 |
Staff View
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| spelling | Protein-protein complexes analysis, modeling and drug design edited by Martin Zacharias London Imperial College Press ©2010 1 Online-Ressource (ix, 390 pages) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index X-ray study of protein-protein complexes and analysis of interfaces / Joel Janin -- A structural perspective on protein-protein interactions in macromolecular assemblies / Ranjit P. Bahadur -- Energetics of protein-protein interactions / Ilian Jelesarov -- Kinetics of biomacromolecular complex formation: theory and experiment / Georgi V. Pachov, Razif R. Gabdoulline and Rebecca C. Wade -- Evolutionary trace of protein functional determinants / Olivier Lichtarge -- Protein-protein docking / Adrien Saladin and Chantal Prevost -- Data-driven docking: using external information to spark the biomolecular rendez-vous / Adrien S.J. Melquiond and Alexandre M.J.J. Bonvin -- High-resolution protein-protein docking / Nir London and Ora Schueler-Furman -- Scoring and refinement of predicted protein-protein complexes / Martin Zacharias -- Motif-mediated protein interactions and their role in disease / Holger Dinkel and Heinrich Sticht -- Prediction and calculation of protein-protein binding affinities and mutation effects / Sébastien Fiorucci, Serge Antonczak and Jérôme Golebiowski -- Small-molecule inhibitors of protein-protein interactions / Thorsten Berg -- Protein dynamics and drug design: the role of molecular simulations / Giulia Morra, Alessandro Genoni and Giorgio Colombo Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge Multiprotein Complexes / chemistry Protein Interaction Mapping Protein Binding Protein Conformation Science Natural history SCIENCE / Life Sciences / Biochemistry bisacsh Protein-protein interactions fast Naturwissenschaft Protein-protein interactions Protein-Protein-Wechselwirkung (DE-588)4745193-2 gnd rswk-swf Arzneimitteldesign (DE-588)4278218-1 gnd rswk-swf Multiproteinkomplex (DE-588)4798068-0 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Protein-Protein-Wechselwirkung (DE-588)4745193-2 s Multiproteinkomplex (DE-588)4798068-0 s Arzneimitteldesign (DE-588)4278218-1 s 2\p DE-604 Zacharias, Martin Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=340801 Aggregator Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Protein-protein complexes analysis, modeling and drug design Multiprotein Complexes / chemistry Protein Interaction Mapping Protein Binding Protein Conformation Science Natural history SCIENCE / Life Sciences / Biochemistry bisacsh Protein-protein interactions fast Naturwissenschaft Protein-protein interactions Protein-Protein-Wechselwirkung (DE-588)4745193-2 gnd Arzneimitteldesign (DE-588)4278218-1 gnd Multiproteinkomplex (DE-588)4798068-0 gnd |
| subject_GND | (DE-588)4745193-2 (DE-588)4278218-1 (DE-588)4798068-0 (DE-588)4143413-4 |
| title | Protein-protein complexes analysis, modeling and drug design |
| title_auth | Protein-protein complexes analysis, modeling and drug design |
| title_exact_search | Protein-protein complexes analysis, modeling and drug design |
| title_full | Protein-protein complexes analysis, modeling and drug design edited by Martin Zacharias |
| title_fullStr | Protein-protein complexes analysis, modeling and drug design edited by Martin Zacharias |
| title_full_unstemmed | Protein-protein complexes analysis, modeling and drug design edited by Martin Zacharias |
| title_short | Protein-protein complexes |
| title_sort | protein protein complexes analysis modeling and drug design |
| title_sub | analysis, modeling and drug design |
| topic | Multiprotein Complexes / chemistry Protein Interaction Mapping Protein Binding Protein Conformation Science Natural history SCIENCE / Life Sciences / Biochemistry bisacsh Protein-protein interactions fast Naturwissenschaft Protein-protein interactions Protein-Protein-Wechselwirkung (DE-588)4745193-2 gnd Arzneimitteldesign (DE-588)4278218-1 gnd Multiproteinkomplex (DE-588)4798068-0 gnd |
| topic_facet | Multiprotein Complexes / chemistry Protein Interaction Mapping Protein Binding Protein Conformation Science Natural history SCIENCE / Life Sciences / Biochemistry Protein-protein interactions Naturwissenschaft Protein-Protein-Wechselwirkung Arzneimitteldesign Multiproteinkomplex Aufsatzsammlung |
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