Molecular and cellular aspects of the serpinopathies and disorders in serpin activity:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hackensack, NJ
World Scientific Pub.
c2007
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references and index SECTION I OVERVIEW OF THE SERPIN SUPERFAMILY; SECTION II LESSONS FROM MODEL ORGANISMS; SECTION III SERPIN PHYSIOLOGY AND PATHOPHYSIOLOGY; SECTION IV CONGENITAL DEFICIENCIES AND SERPINOPATHIES; Editors; Contributors; Serpinopathies Foreword; Serpinopathies Preface; Index Serpins constitute a superfamily of proteins that possess a unique tertiary structure and mechanism of proteinase inhibition. In humans, serpins constitute 10% of the plasma proteins and are best known as critical regulators of both the thrombotic and fibrinolytic systems. Serpins also participate in the regulation of the complement cascade, angiogenesis, tumor metastasis, apoptosis and innate immunity. Considering the importance of these molecules in regulating proteolytic cascades, it is not surprising to find that loss- and gain-of-function mutations result in significant human diseases. Ma |
| Beschreibung: | 1 Online-Ressource (xxi, 639 p.) |
| ISBN: | 9789812707543 9812707549 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV043130405 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 151126s2007 |||| o||u| ||||||eng d | ||
| 020 | |a 9789812707543 |c electronic bk. |9 978-981-270-754-3 | ||
| 020 | |a 9812707549 |c electronic bk. |9 981-270-754-9 | ||
| 035 | |a (OCoLC)172988087 | ||
| 035 | |a (DE-599)BVBBV043130405 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-1046 |a DE-1047 | ||
| 082 | 0 | |a 612.01575 |2 22 | |
| 245 | 1 | 0 | |a Molecular and cellular aspects of the serpinopathies and disorders in serpin activity |c editors, Gary A. Silverman, David A. Lomas |
| 264 | 1 | |a Hackensack, NJ |b World Scientific Pub. |c c2007 | |
| 300 | |a 1 Online-Ressource (xxi, 639 p.) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Includes bibliographical references and index | ||
| 500 | |a SECTION I OVERVIEW OF THE SERPIN SUPERFAMILY; SECTION II LESSONS FROM MODEL ORGANISMS; SECTION III SERPIN PHYSIOLOGY AND PATHOPHYSIOLOGY; SECTION IV CONGENITAL DEFICIENCIES AND SERPINOPATHIES; Editors; Contributors; Serpinopathies Foreword; Serpinopathies Preface; Index | ||
| 500 | |a Serpins constitute a superfamily of proteins that possess a unique tertiary structure and mechanism of proteinase inhibition. In humans, serpins constitute 10% of the plasma proteins and are best known as critical regulators of both the thrombotic and fibrinolytic systems. Serpins also participate in the regulation of the complement cascade, angiogenesis, tumor metastasis, apoptosis and innate immunity. Considering the importance of these molecules in regulating proteolytic cascades, it is not surprising to find that loss- and gain-of-function mutations result in significant human diseases. Ma | ||
| 650 | 7 | |a MEDICAL / Biochemistry |2 bisacsh | |
| 650 | 7 | |a Serpins |2 fast | |
| 650 | 7 | |a Serpins / Physiological effect |2 fast | |
| 650 | 4 | |a Serpins | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Serpins | |
| 650 | 4 | |a Serpins |x Physiological effect | |
| 700 | 1 | |a Silverman, Gary A. |e Sonstige |4 oth | |
| 700 | 1 | |a Lomas, David A. |e Sonstige |4 oth | |
| 856 | 4 | 0 | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850 |x Aggregator |3 Volltext |
| 912 | |a ZDB-4-EBA | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-028554596 | ||
| 966 | e | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850 |l FAW01 |p ZDB-4-EBA |q FAW_PDA_EBA |x Aggregator |3 Volltext | |
| 966 | e | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850 |l FAW02 |p ZDB-4-EBA |q FAW_PDA_EBA |x Aggregator |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804175569115414528 |
|---|---|
| any_adam_object | |
| building | Verbundindex |
| bvnumber | BV043130405 |
| collection | ZDB-4-EBA |
| ctrlnum | (OCoLC)172988087 (DE-599)BVBBV043130405 |
| dewey-full | 612.01575 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.01575 |
| dewey-search | 612.01575 |
| dewey-sort | 3612.01575 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02674nmm a2200457zc 4500</leader><controlfield tag="001">BV043130405</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">151126s2007 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9789812707543</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">978-981-270-754-3</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9812707549</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">981-270-754-9</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)172988087</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043130405</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-1046</subfield><subfield code="a">DE-1047</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">612.01575</subfield><subfield code="2">22</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Molecular and cellular aspects of the serpinopathies and disorders in serpin activity</subfield><subfield code="c">editors, Gary A. Silverman, David A. Lomas</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Hackensack, NJ</subfield><subfield code="b">World Scientific Pub.</subfield><subfield code="c">c2007</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (xxi, 639 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">SECTION I OVERVIEW OF THE SERPIN SUPERFAMILY; SECTION II LESSONS FROM MODEL ORGANISMS; SECTION III SERPIN PHYSIOLOGY AND PATHOPHYSIOLOGY; SECTION IV CONGENITAL DEFICIENCIES AND SERPINOPATHIES; Editors; Contributors; Serpinopathies Foreword; Serpinopathies Preface; Index</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Serpins constitute a superfamily of proteins that possess a unique tertiary structure and mechanism of proteinase inhibition. In humans, serpins constitute 10% of the plasma proteins and are best known as critical regulators of both the thrombotic and fibrinolytic systems. Serpins also participate in the regulation of the complement cascade, angiogenesis, tumor metastasis, apoptosis and innate immunity. Considering the importance of these molecules in regulating proteolytic cascades, it is not surprising to find that loss- and gain-of-function mutations result in significant human diseases. Ma</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Biochemistry</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Serpins</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Serpins / Physiological effect</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Serpins</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medizin</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Serpins</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Serpins</subfield><subfield code="x">Physiological effect</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Silverman, Gary A.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lomas, David A.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-4-EBA</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-028554596</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850</subfield><subfield code="l">FAW01</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FAW_PDA_EBA</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850</subfield><subfield code="l">FAW02</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FAW_PDA_EBA</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV043130405 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:18:22Z |
| institution | BVB |
| isbn | 9789812707543 9812707549 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028554596 |
| oclc_num | 172988087 |
| open_access_boolean | |
| owner | DE-1046 DE-1047 |
| owner_facet | DE-1046 DE-1047 |
| physical | 1 Online-Ressource (xxi, 639 p.) |
| psigel | ZDB-4-EBA ZDB-4-EBA FAW_PDA_EBA |
| publishDate | 2007 |
| publishDateSearch | 2007 |
| publishDateSort | 2007 |
| publisher | World Scientific Pub. |
| record_format | marc |
| spelling | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity editors, Gary A. Silverman, David A. Lomas Hackensack, NJ World Scientific Pub. c2007 1 Online-Ressource (xxi, 639 p.) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index SECTION I OVERVIEW OF THE SERPIN SUPERFAMILY; SECTION II LESSONS FROM MODEL ORGANISMS; SECTION III SERPIN PHYSIOLOGY AND PATHOPHYSIOLOGY; SECTION IV CONGENITAL DEFICIENCIES AND SERPINOPATHIES; Editors; Contributors; Serpinopathies Foreword; Serpinopathies Preface; Index Serpins constitute a superfamily of proteins that possess a unique tertiary structure and mechanism of proteinase inhibition. In humans, serpins constitute 10% of the plasma proteins and are best known as critical regulators of both the thrombotic and fibrinolytic systems. Serpins also participate in the regulation of the complement cascade, angiogenesis, tumor metastasis, apoptosis and innate immunity. Considering the importance of these molecules in regulating proteolytic cascades, it is not surprising to find that loss- and gain-of-function mutations result in significant human diseases. Ma MEDICAL / Biochemistry bisacsh Serpins fast Serpins / Physiological effect fast Serpins Medizin Serpins Physiological effect Silverman, Gary A. Sonstige oth Lomas, David A. Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850 Aggregator Volltext |
| spellingShingle | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity MEDICAL / Biochemistry bisacsh Serpins fast Serpins / Physiological effect fast Serpins Medizin Serpins Physiological effect |
| title | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity |
| title_auth | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity |
| title_exact_search | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity |
| title_full | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity editors, Gary A. Silverman, David A. Lomas |
| title_fullStr | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity editors, Gary A. Silverman, David A. Lomas |
| title_full_unstemmed | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity editors, Gary A. Silverman, David A. Lomas |
| title_short | Molecular and cellular aspects of the serpinopathies and disorders in serpin activity |
| title_sort | molecular and cellular aspects of the serpinopathies and disorders in serpin activity |
| topic | MEDICAL / Biochemistry bisacsh Serpins fast Serpins / Physiological effect fast Serpins Medizin Serpins Physiological effect |
| topic_facet | MEDICAL / Biochemistry Serpins Serpins / Physiological effect Medizin Serpins Physiological effect |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=203850 |
| work_keys_str_mv | AT silvermangarya molecularandcellularaspectsoftheserpinopathiesanddisordersinserpinactivity AT lomasdavida molecularandcellularaspectsoftheserpinopathiesanddisordersinserpinactivity |