Biologically-responsive hybrid biomaterials: a reference for material scientists and bioengineers
Gespeichert in:
Format: | Elektronisch E-Book |
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Sprache: | English |
Veröffentlicht: |
New Jersey
World Scientific
©2010
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Schlagworte: | |
Online-Zugang: | FAW01 FAW02 Volltext |
Beschreibung: | Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials Includes bibliographical references and index Engineering the tissue extracellular matrix with hybrid biomaterials -- Synthesis, characterization and self-assembly -- Bulk and solution properties of peptide-polymer conjugates -- Polymer-peptide conjugate networks: formation, swelling and degradation -- Peptide self-assembly biomaterials design and application -- Micropatterned polymer structures for cell and tissue engineering -- Synthesis and in vitro/in vivo response to peptide-polymer conjugates -- Hybrid biomaterials in drug delivery and molecular recognition -- Synthesis of multi-epitopic glycopeptide-based cancer vaccines -- Stimuli-sensitive particles for drug delivery -- Design and synthesis of endosomolytic conjugated polyaspartamide for cytosolic drug delivery -- Engineering of cell-penetrating peptide-conjugated intracellular delivery systems -- Cell responsive biomaterials in tissue engineering -- Biomimetic matrices for integrin-mediated cell adhesion -- Engineering artificial stem cell niches -- Engineering peptides in hydrogels for cartilage tissue regeneration -- Biomimetic materials for engineering of neural tissues: control of cell adhesion and guiding neural cell outgrowth with peptide-conjugated polymer structures -- Hybrid biomaterials for engineering vascular tissues -- Dynamic cell culture methods for functionalized biomaterials |
Beschreibung: | 1 Online-Ressource (vi, 423 pages) |
ISBN: | 9789814295673 9789814295680 9814295671 981429568X |
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500 | |a Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials | ||
500 | |a Includes bibliographical references and index | ||
500 | |a Engineering the tissue extracellular matrix with hybrid biomaterials -- Synthesis, characterization and self-assembly -- Bulk and solution properties of peptide-polymer conjugates -- Polymer-peptide conjugate networks: formation, swelling and degradation -- Peptide self-assembly biomaterials design and application -- Micropatterned polymer structures for cell and tissue engineering -- Synthesis and in vitro/in vivo response to peptide-polymer conjugates -- Hybrid biomaterials in drug delivery and molecular recognition -- Synthesis of multi-epitopic glycopeptide-based cancer vaccines -- Stimuli-sensitive particles for drug delivery -- Design and synthesis of endosomolytic conjugated polyaspartamide for cytosolic drug delivery -- Engineering of cell-penetrating peptide-conjugated intracellular delivery systems -- Cell responsive biomaterials in tissue engineering -- Biomimetic matrices for integrin-mediated cell adhesion -- Engineering artificial stem cell niches -- Engineering peptides in hydrogels for cartilage tissue regeneration -- Biomimetic materials for engineering of neural tissues: control of cell adhesion and guiding neural cell outgrowth with peptide-conjugated polymer structures -- Hybrid biomaterials for engineering vascular tissues -- Dynamic cell culture methods for functionalized biomaterials | ||
650 | 4 | |a Biocompatible Materials | |
650 | 4 | |a Biomimetic Materials | |
650 | 4 | |a Cells, Cultured | |
650 | 4 | |a Drug Delivery Systems | |
650 | 4 | |a Structure-Activity Relationship | |
650 | 4 | |a Tissue Engineering | |
650 | 4 | |a Medicine | |
650 | 7 | |a TECHNOLOGY & ENGINEERING / Biomedical |2 bisacsh | |
650 | 7 | |a MEDICAL / Family & General Practice |2 bisacsh | |
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650 | 7 | |a Biomedical materials |2 fast | |
650 | 4 | |a Medizin | |
650 | 4 | |a Biomedical materials | |
700 | 1 | |a Jabbari, E. |e Sonstige |4 oth | |
700 | 1 | |a Khademhosseini, Ali |e Sonstige |4 oth | |
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Datensatz im Suchindex
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---|---|
any_adam_object | |
building | Verbundindex |
bvnumber | BV043123988 |
collection | ZDB-4-EBA |
ctrlnum | (OCoLC)681789053 (DE-599)BVBBV043123988 |
dewey-full | 610.28 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 610 - Medicine and health |
dewey-raw | 610.28 |
dewey-search | 610.28 |
dewey-sort | 3610.28 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
format | Electronic eBook |
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id | DE-604.BV043123988 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T07:18:10Z |
institution | BVB |
isbn | 9789814295673 9789814295680 9814295671 981429568X |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028548178 |
oclc_num | 681789053 |
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physical | 1 Online-Ressource (vi, 423 pages) |
psigel | ZDB-4-EBA ZDB-4-EBA FAW_PDA_EBA |
publishDate | 2010 |
publishDateSearch | 2010 |
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publisher | World Scientific |
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spelling | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers editors, E. Jabbari, A. Khademhosseini New Jersey World Scientific ©2010 1 Online-Ressource (vi, 423 pages) txt rdacontent c rdamedia cr rdacarrier Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials Includes bibliographical references and index Engineering the tissue extracellular matrix with hybrid biomaterials -- Synthesis, characterization and self-assembly -- Bulk and solution properties of peptide-polymer conjugates -- Polymer-peptide conjugate networks: formation, swelling and degradation -- Peptide self-assembly biomaterials design and application -- Micropatterned polymer structures for cell and tissue engineering -- Synthesis and in vitro/in vivo response to peptide-polymer conjugates -- Hybrid biomaterials in drug delivery and molecular recognition -- Synthesis of multi-epitopic glycopeptide-based cancer vaccines -- Stimuli-sensitive particles for drug delivery -- Design and synthesis of endosomolytic conjugated polyaspartamide for cytosolic drug delivery -- Engineering of cell-penetrating peptide-conjugated intracellular delivery systems -- Cell responsive biomaterials in tissue engineering -- Biomimetic matrices for integrin-mediated cell adhesion -- Engineering artificial stem cell niches -- Engineering peptides in hydrogels for cartilage tissue regeneration -- Biomimetic materials for engineering of neural tissues: control of cell adhesion and guiding neural cell outgrowth with peptide-conjugated polymer structures -- Hybrid biomaterials for engineering vascular tissues -- Dynamic cell culture methods for functionalized biomaterials Biocompatible Materials Biomimetic Materials Cells, Cultured Drug Delivery Systems Structure-Activity Relationship Tissue Engineering Medicine TECHNOLOGY & ENGINEERING / Biomedical bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Allied Health Services / Medical Technology bisacsh MEDICAL / Biotechnology bisacsh MEDICAL / Lasers in Medicine bisacsh Biomedical materials fast Medizin Biomedical materials Jabbari, E. Sonstige oth Khademhosseini, Ali Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=340740 Aggregator Volltext |
spellingShingle | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers Biocompatible Materials Biomimetic Materials Cells, Cultured Drug Delivery Systems Structure-Activity Relationship Tissue Engineering Medicine TECHNOLOGY & ENGINEERING / Biomedical bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Allied Health Services / Medical Technology bisacsh MEDICAL / Biotechnology bisacsh MEDICAL / Lasers in Medicine bisacsh Biomedical materials fast Medizin Biomedical materials |
title | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers |
title_auth | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers |
title_exact_search | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers |
title_full | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers editors, E. Jabbari, A. Khademhosseini |
title_fullStr | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers editors, E. Jabbari, A. Khademhosseini |
title_full_unstemmed | Biologically-responsive hybrid biomaterials a reference for material scientists and bioengineers editors, E. Jabbari, A. Khademhosseini |
title_short | Biologically-responsive hybrid biomaterials |
title_sort | biologically responsive hybrid biomaterials a reference for material scientists and bioengineers |
title_sub | a reference for material scientists and bioengineers |
topic | Biocompatible Materials Biomimetic Materials Cells, Cultured Drug Delivery Systems Structure-Activity Relationship Tissue Engineering Medicine TECHNOLOGY & ENGINEERING / Biomedical bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Allied Health Services / Medical Technology bisacsh MEDICAL / Biotechnology bisacsh MEDICAL / Lasers in Medicine bisacsh Biomedical materials fast Medizin Biomedical materials |
topic_facet | Biocompatible Materials Biomimetic Materials Cells, Cultured Drug Delivery Systems Structure-Activity Relationship Tissue Engineering Medicine TECHNOLOGY & ENGINEERING / Biomedical MEDICAL / Family & General Practice MEDICAL / Allied Health Services / Medical Technology MEDICAL / Biotechnology MEDICAL / Lasers in Medicine Biomedical materials Medizin |
url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=340740 |
work_keys_str_mv | AT jabbarie biologicallyresponsivehybridbiomaterialsareferenceformaterialscientistsandbioengineers AT khademhosseiniali biologicallyresponsivehybridbiomaterialsareferenceformaterialscientistsandbioengineers |