Therapeutic oligonucleotides:
Gespeichert in:
Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Cambridge RSC Pub. c2008
Schriftenreihe:RSC biomolecular sciences
Schlagworte:
Online-Zugang:FAW01
FAW02
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Beschreibung:Includes bibliographical references and index
The role of backbone modifications in oligonucleotide-based strategies -- Genasense (G3139) : an antisense Bcl-2 oligodeoxyribonucleotide with substantial clinical activity and a complex mechanism of action -- Antisense morpholino oligomers and their peptide conjugates -- Peptide-peptide nucleic acid conjugates for modulation of gene expression -- Locked nucleic acid: properties and therapeutic aspects -- Immune stimulatory oligonucleotides -- Decoy oligodeoxynucleotides to treat inflammatory diseases -- AS1411 : development of an anticancer aptamer -- Spiegelmer NOX-E36 for renal diseases -- Strategies for the delivery of oligonucleotides in vivo -- Lipid-mediated in vivo delivery of small interfering RNAs -- Vector-mediated and viral delivery of short hairpin RNAs -- Development of an RNAi-based gene therapy against HIV-1 -- RNA based therapies for treatment of HIV infection
Beschreibung:1 Online-Ressource (xvii, 343 p.)
ISBN:0854041168
1847558275
9780854041169
9781847558275

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